Data Sheet 1_The relationship between inflammatory factors and heart failure: evidence based on bidirectional Mendelian randomization analysis.zip حسب Xuanchun Huang (17359851)

"…</p>Methods<p>We conducted our study using the bidirectional Mendelian randomization approach. …"

Image 1_Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation... حسب Todor Chobanov (22288636)

"…Statistical modeling demonstrates that contemporary Croatian populations formed through three distinct migration waves, with 50%–60% total Slavic ancestry and 20%–25% pre-Slavic Balkan continuity. Significantly, we identified individuals with Slavic genetic profiles in prestigious Avar burial contexts, questioning established understanding of social hierarchies within the Khaganate. …"

DataSheet1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.zip حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

DataSheet1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.zip حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

Data Sheet 1_Wooden breast myopathy is characterized by satellite cell dysfunction and syndecan-4 shedding.pdf حسب Lucie Pejšková (20467025)

"…Moreover, we showed that SDC4 overexpression is linked to reduced proliferation in MuSCs and affected myogenesis. …"

Image 7_Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation... حسب Todor Chobanov (22288636)

"…Statistical modeling demonstrates that contemporary Croatian populations formed through three distinct migration waves, with 50%–60% total Slavic ancestry and 20%–25% pre-Slavic Balkan continuity. Significantly, we identified individuals with Slavic genetic profiles in prestigious Avar burial contexts, questioning established understanding of social hierarchies within the Khaganate. …"

Supplementary Material for: From childhood to adolescence: Long-term trends in severe obesity in German youth (2002–2023) حسب figshare admin karger (2628495)

"…Furthermore, we analyzed subgroup differences and assessed how the COVID-19 pandemic affected weight status. …"

Table 2_Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation... حسب Todor Chobanov (22288636)

"…Statistical modeling demonstrates that contemporary Croatian populations formed through three distinct migration waves, with 50%–60% total Slavic ancestry and 20%–25% pre-Slavic Balkan continuity. Significantly, we identified individuals with Slavic genetic profiles in prestigious Avar burial contexts, questioning established understanding of social hierarchies within the Khaganate. …"

<b>The Bacterial OMP Amyloids Modulate</b><b> </b><b>α</b><b>-Synuclein and Amyloid-</b><b>β</b><b> </b><b>Aggregation</b> حسب Maksim Sulatsky (21562922)

"…In contrast, amyloid-β fibrils showed more extensive structural changes, with modifications to both the "fuzzy coat" and β-sheet core, accompanied by decreased clustering tendency and significantly reduced toxicity for mammalian neuroblastoma and epithelial adenocarcinoma cell lines. …"

Image2_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

Image 6_Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation... حسب Todor Chobanov (22288636)

"…Statistical modeling demonstrates that contemporary Croatian populations formed through three distinct migration waves, with 50%–60% total Slavic ancestry and 20%–25% pre-Slavic Balkan continuity. Significantly, we identified individuals with Slavic genetic profiles in prestigious Avar burial contexts, questioning established understanding of social hierarchies within the Khaganate. …"

ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer حسب Ana García-García (17779885)

"…Initially, we show the direct regulation of ELOVLs expression by c-MYC in various PDAC mouse models and cell lines, elucidating its upregulation during transformation and tumor progression. …"

Image 2_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif حسب Kai Liu (159026)

"…Common comorbidities in the diabetic group were hypertension, cerebrovascular disease, chronic kidney disease and cardiovascular disease. We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …"

Image2_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

Image 2_Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation... حسب Todor Chobanov (22288636)

"…Statistical modeling demonstrates that contemporary Croatian populations formed through three distinct migration waves, with 50%–60% total Slavic ancestry and 20%–25% pre-Slavic Balkan continuity. Significantly, we identified individuals with Slavic genetic profiles in prestigious Avar burial contexts, questioning established understanding of social hierarchies within the Khaganate. …"

Image 3_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif حسب Kai Liu (159026)

"…Common comorbidities in the diabetic group were hypertension, cerebrovascular disease, chronic kidney disease and cardiovascular disease. We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …"

Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of <i>Pseudomonas aeruginosa</i> in an organotypic 3D lung epithelial cell model حسب Merel Wauters (21333023)

"…Compared to the <i>lasB</i> mutant, the wild-type strain significantly decreased inflammation by degrading MCP-1, IL-1β, GM-CSF, and IL-8. …"

Image1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

Image 1_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif حسب Kai Liu (159026)

"…Common comorbidities in the diabetic group were hypertension, cerebrovascular disease, chronic kidney disease and cardiovascular disease. We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …"

Data Sheet 5_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

"…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"