Image 1_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.tif by Jianyan Pan (20681864)

“…However, the heterogeneity of polyamine metabolism and its effects on the immune microenvironment and response to immunotherapy in HCC remain unclear. Here, we aimed to investigate the prognostic and immunotherapeutic implications of polyamine metabolism in HCC. …”

Image 2_ZKSCAN3 promotes ovarian cancer cell proliferation by increasing HSPB1 expression.pdf by Qian Ke (9164990)

“…HSPB1 expression is significantly decreased upon suppressing ZKSCAN3 expression. …”

Data Sheet 2_Single-cell transcriptomics reveals predominantly inflammatory endothelial cell responses and suppressed vascular repair in silicosis.pdf by Dongli Cao (18700097)

“…</p>Results<p>We identified two functionally distinct endothelial subpopulations: 1. …”

Data Sheet 3_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.csv by Jianyan Pan (20681864)

“…However, the heterogeneity of polyamine metabolism and its effects on the immune microenvironment and response to immunotherapy in HCC remain unclear. Here, we aimed to investigate the prognostic and immunotherapeutic implications of polyamine metabolism in HCC. …”

Supplementary file 1_ZKSCAN3 promotes ovarian cancer cell proliferation by increasing HSPB1 expression.docx by Qian Ke (9164990)

“…HSPB1 expression is significantly decreased upon suppressing ZKSCAN3 expression. …”

Data Sheet 4_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.csv by Jianyan Pan (20681864)

“…However, the heterogeneity of polyamine metabolism and its effects on the immune microenvironment and response to immunotherapy in HCC remain unclear. Here, we aimed to investigate the prognostic and immunotherapeutic implications of polyamine metabolism in HCC. …”

Data Sheet 1_Heterogeneity in polyamine metabolism dictates prognosis and immune checkpoint blockade response in hepatocellular carcinoma.csv by Jianyan Pan (20681864)

“…However, the heterogeneity of polyamine metabolism and its effects on the immune microenvironment and response to immunotherapy in HCC remain unclear. Here, we aimed to investigate the prognostic and immunotherapeutic implications of polyamine metabolism in HCC. …”

Table 1_Single-cell transcriptomics reveals predominantly inflammatory endothelial cell responses and suppressed vascular repair in silicosis.docx by Dongli Cao (18700097)

“…</p>Results<p>We identified two functionally distinct endothelial subpopulations: 1. …”

Minimal data sets. by Razia Rashid Rahil (22772495)

“…Sphingolipids such as ceramide (CER) mediates inflammation and VC in the vascular tissue. We investigated whether evogliptin ameliorate phenotypic transition and pyroptosis in VSMCs as underlying cause of VC. …”

Data Sheet 2_Preventive hyperbaric oxygen therapy improves acute graft-versus-host disease by activating the Nrf2/HO-1 pathway.docx by Chao Xue (503328)

“…</p>Results<p>We found that HBOT alleviated aGVHD in mice, which was associated with a significantly prolonged overall survival (OS) and reduced pathological injury, whereas Nrf2 inhibition had the opposite effect. …”

Table_1_RETRACTED: miR-335 Targets LRRK2 and Mitigates Inflammation in Parkinson’s Disease.DOCX by Sara R. Oliveira (10972152)

“…LRRK2-Wt-induced proinflammatory gene expression was also significantly reduced by miR-335 overexpression. Finally, in SH-SY5Y neuroblastoma cells, miR-335 decreased the expression of pro-inflammatory genes triggered by α-synuclein. …”

Data Sheet 1_Preventive hyperbaric oxygen therapy improves acute graft-versus-host disease by activating the Nrf2/HO-1 pathway.pdf by Chao Xue (503328)

“…</p>Results<p>We found that HBOT alleviated aGVHD in mice, which was associated with a significantly prolonged overall survival (OS) and reduced pathological injury, whereas Nrf2 inhibition had the opposite effect. …”

pone.0337200.t001 - by Razia Rashid Rahil (22772495)

“…Sphingolipids such as ceramide (CER) mediates inflammation and VC in the vascular tissue. We investigated whether evogliptin ameliorate phenotypic transition and pyroptosis in VSMCs as underlying cause of VC. …”

Data Sheet 1_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.pdf by Arjanneke F. van de Merbel (5809940)

“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”

Data Sheet 2_Anti-neoplastic effects of the antipsychotic drug penfluridol in preclinical prostate cancer models.docx by Arjanneke F. van de Merbel (5809940)

“…</p>Results<p>Penfluridol significantly reduced the viability of a panel of human PCa cells, induced apoptosis by increasing caspase-3/7 levels and decreased the number of PCa stem cells in vitro. …”

Supplementary Material for: Single intraluminal delivery of a nitric oxide-donor results in inhibition of intimal thickening in the rabbit femoral artery by Böttger P. (20682794)

“…Linsidomine treatment decreased the intima media ratio significantly (0.65±0.05 vs 1,2±0.2 intima-media-ratio, p<0.05). …”

Whole 16S rRNA gene sequencing reveals differences in the oral microbiota of healthy individuals infected with oral HPV by Toby I. Maidment (15296219)

“…Statistical analysis of alpha- and beta-diversity, as well as taxonomic composition (differential abundance testing), were used to determine differences between-subject groups.</p> <p>We demonstrated (1) significant differences in the abundance of <i>Streptococcus salivarius</i> in oral HPV-negative males; (2) males with low-risk HPV had an increased abundance of several species and (3) decreased abundance of <i>Streptococcus salivarius</i> and <i>Streptococcus parasanguinis</i>. …”

Image 1_Iodine-131 induces ferroptosis and synergizes with sulfasalazine in differentiated thyroid cancer cells via suppressing SLC7A11.tif by Li Ling (424480)

“…Moreover, the combination of SAS and ¹³¹I significantly increased the MDA levels and lipid peroxidation, decreased the GSH levels, and suppressed the expression of SLC7A11 and GPX4, while SLC7A11 knockdown significantly enhanced ferroptosis-related markers in DTC cells. …”

Data Sheet 1_Molecular and clinical insights into HIV-associated and HIV-negative aggressive B-cell lymphomas: prognostic quantitative biomarker analysis and therapeutic implicatio... by Liming Liu (107470)

“…Immunophenotyping revealed a GCB-like phenotype in HALs, characterized by elevated CD10 and BCL6 expression and decreased MUM1 and BCL2 expression. Patients with HALs had significantly shorter survival (median: 32.1 vs. 46.1 months, P < 0.001). …”

Table 1_Remimazolam used for sedation during spinal anesthesia puncture provides faster sedation effect and increase recovery rate compared to midazolam: a randomized controlled tr... by Peipei Sun (416208)

“…Both groups showed significant within-group decreases in mean arterial pressure during sedation (remimazolam: from 81.5 to 75 mmHg; midazolam: from 81.7 to 72.4 mmHg; P < 0.05), with no significant inter-group difference. …”