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largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), teer decrease (Expand Search)
nn decrease » _ decrease (Expand Search), a decrease (Expand Search), gy decreased (Expand Search)
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7021
<i>DANCR</i> regulated genes in SK-MEL-28 cells.
Published 2025“…MITF and c-MYC, key melanoma transcription factors, regulate human <i>DANCR</i> expression and melanoma patients with high <i>DANCR</i> display significantly decreased survival. <i>DANCR</i> is a melanoma oncogene that controls cancer-associated gene expression networks to promote human melanoma cell proliferation and migration. …”
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7022
Table1_Identification of telomere-related lncRNAs and immunological analysis in ovarian cancer.docx
Published 2024“…Additionally, immune infiltration, tumor mutational load (TMB), and drug sensitivity were evaluated. We validated the expression levels of prognostic genes. …”
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7023
Image 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.tif
Published 2025“…Finally, to investigate the expression and function of ACTR6 in liver cancer cells, real-time qPCR (RT-qPCR) assays, CCK-8, clone creation, cell cycle, and transwell migration and invasion experiments were carried out.</p>Results<p>We found that, in addition to ACTR3C, 17 ARPs were significantly overexpressed in HCC compared with normal tissues. …”
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7024
Table 5_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx
Published 2025“…Finally, qRT-PCR confirmed the differential expression of key genes in clinical samples.</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”
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7025
Image 1_Fraxin modulates lipid metabolism as well as gut flora to avert NAFLD.tif
Published 2025“…GO and KEGG analyses suggested that fraxin primarily treats NAFLD by modulating lipid metabolism and atherosclerosis-related signaling pathways. In vivo, fraxin significantly lowered liver index and visceral fat accumulation, reduced serum levels of “interleukin-6 (IL-6),” “aspartate aminotransferase,” “tumor necrosis factor-α (TNF-α)” and “alanine aminotransferase,” and decreased hepatic TG content. …”
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7026
Table 2_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx
Published 2025“…Finally, qRT-PCR confirmed the differential expression of key genes in clinical samples.</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”
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7027
Chromatin accessibility profiling of Treg cells in acute urticaria
Published 2025“…However, the role of Tregs in the pathogenesis of acute urticaria is unclear. In this study, we found that the frequency of Tregs in peripheral blood mononuclear cells (PBMCs) was decreased in patients with acute urticaria compared with normal controls by flow cytometry. …”
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7028
Data Sheet 1_Preliminary evaluation of a novel serotype O foot-and-mouth disease mRNA vaccine.docx
Published 2025“…The viral load results demonstrated that the vaccine group significantly reduced viral copy numbers in serum and effectively decreased the concentration of the inflammatory cytokine IL-1β. …”
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7029
Prognostic value of cardiac troponin I in acute ischemic stroke patients treated with reperfusion therapy: a multicenter retrospective cohort study
Published 2025“…Elevated cTnI was not significantly associated with sICH (OR:3.75, 95%CI 0.52–27.21, <i>p</i> = 0.19), but was independently associated with increased in-hospital mortality (OR:1.96, 95%CI 1.62–6.20, <i>p</i> = 0.025) and decreased odds of good functional outcome at 30 days (OR:0.40, 95%CI 0.19–0.84, <i>p</i> = 0.016). …”
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7030
Data_Sheet_1_Compound effects of biochar application and irrigation on soil water and temperature transport.docx
Published 2024“…However, higher levels of AOBA adversely affected WPSWS, with the C10 treatment showing the maximum improvement in WPSWS, registering an average increase of 6.77, 7.49, and 11.16% compared to the C0, C20, and C30 treatments, respectively. We observed that an increase in irrigation amount significantly elevated accumulated soil evaporation (ASE) and WPSWS but led to a reduction in accumulated soil temperature (AST). …”
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7031
Image 2_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.tif
Published 2025“…Finally, to investigate the expression and function of ACTR6 in liver cancer cells, real-time qPCR (RT-qPCR) assays, CCK-8, clone creation, cell cycle, and transwell migration and invasion experiments were carried out.</p>Results<p>We found that, in addition to ACTR3C, 17 ARPs were significantly overexpressed in HCC compared with normal tissues. …”
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7032
DataSheet1_Identification of telomere-related lncRNAs and immunological analysis in ovarian cancer.docx
Published 2024“…Additionally, immune infiltration, tumor mutational load (TMB), and drug sensitivity were evaluated. We validated the expression levels of prognostic genes. …”
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7033
Data Sheet 1_Research on the effect of LAMP1 in the development and progression of ccRCC and its potential mechanism with LC3C-mediated autophagy.docx
Published 2024“…</p>Results<p>Bioinformatics analysis revealed significant underexpression of LAMP1 in ccRCC (P<0.001), which correlated with poorer prognosis. …”
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7034
Supplementary file 1_Single-cell and bulk transcriptomic analyses reveal PANoptosis-associated immune dysregulation of fibroblasts in periodontitis.zip
Published 2025“…However, its precise role and underlying mechanisms in periodontitis (PD) remain unclear.</p>Methods<p>We analyzed single-cell RNA sequencing (scRNA-seq) on gingival tissues from PD patients and healthy individuals to profile cellular composition and quantify cell-type distributions. …”
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7035
Table 3_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.xlsx
Published 2025“…Finally, qRT-PCR confirmed the differential expression of key genes in clinical samples.</p>Results<p>We identified 25 ribosome biogenesis-related differentially expressed genes, which were significantly enriched in RNA degradation and rRNA processing. …”
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7036
Table 1_Expression, prognosis and preliminary investigation of the mechanism of action of ACTR6, a member of the ARPs gene family, in hepatocellular carcinoma.docx
Published 2025“…Finally, to investigate the expression and function of ACTR6 in liver cancer cells, real-time qPCR (RT-qPCR) assays, CCK-8, clone creation, cell cycle, and transwell migration and invasion experiments were carried out.</p>Results<p>We found that, in addition to ACTR3C, 17 ARPs were significantly overexpressed in HCC compared with normal tissues. …”
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7037
<b>Empagliflozin reduces left ventricular mass increase and improves cardiomyocyte hypertrophy after 5/6 nephrectomy.</b>
Published 2025“…<p dir="ltr"><b>Methods and Results</b><b>: </b>Using a 5/6 nephrectomy rat model to induce cardiorenal syndrome, we administered two doses of Empagliflozin (3 mg/kg/day and 15 mg/kg/day) via gavage for 95 days, with Telmisartan as a positive control. …”
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7038
Table 2_Long-term outcomes of platinum-based chemotherapy for T4 stage sinonasal adenoid cystic carcinoma.docx
Published 2025“…Besides, chemotherapy significantly decreased 10-year OS (27.9% vs. 58.8%, P = 0.034) compared with the no-chemotherapy group. …”
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7039
Table 1_Long-term outcomes of platinum-based chemotherapy for T4 stage sinonasal adenoid cystic carcinoma.doc
Published 2025“…Besides, chemotherapy significantly decreased 10-year OS (27.9% vs. 58.8%, P = 0.034) compared with the no-chemotherapy group. …”
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7040
<b>Chemical components, emission dynamics, and external immune functions of red palm weevil larval volatiles in response to changes in developmental stages and pathogen stress</b>
Published 2025“…However, the volatile compositions, emission patterns, and external immune functions of the red palm weevil (RPW), a major invasive pest, are largely unknown. In this study, we examined RPW larval volatiles, analyzing their chemical composition and emission patterns across developmental stages and under pathogen stress. …”