Data Sheet 1_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with f... حسب Huihui Zhu (4483621)

"…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …"

Increased COX6A2 promotes pancreatic β-cell apoptosis and is suppressed in diabetic GK rats after Roux-en-Y gastric bypass حسب Xiangchen Kong (9500542)

"…We found that RYGB significantly reduced β-cell apoptosis, accompanied by decreased COX6A2 expression in islets from diabetic Goto-Kakizaki (GK) rats. …"

Table 1_Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases.xlsx حسب Yan Li (23143)

"…Furthermore, intermediate or healthy lifestyles significantly decreased the age-related risk of stroke, chronic liver disease, chronic kidney disease (CKD), osteoporosis, osteoarthritis, and hypertension. …"

Data Sheet 1_Isobavachalcone ameliorates Alzheimer disease pathology by autophagy-mediated clearance of amyloid beta and inhibition of NLRP3 inflammasome in primary astrocytes and... حسب Dilpreet Kour (10872766)

"…To this end, we identified isobavachalcone (IBC), a natural compound with dual pharmacological activity in reducing Aβ plaques and neuroinflammation.…"

Supplementary file 1_Metabolites mediate the effects of healthy lifestyles on the risks of common age-related diseases.docx حسب Yan Li (23143)

"…Furthermore, intermediate or healthy lifestyles significantly decreased the age-related risk of stroke, chronic liver disease, chronic kidney disease (CKD), osteoporosis, osteoarthritis, and hypertension. …"

Table 7_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... حسب Minseo Kim (773205)

"…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …"

Drug-Free Mesoporous Silica Nanoparticles Enable Suppression of Cancer Metastasis and Confer Survival Advantages to Mice with Tumor Xenografts حسب Yu-Tse Lee (19944891)

"…We attributed the improved survival to the antimetastatic capabilities of MSN-PEG/TA 25. …"

Molecular hydrogen mitigates NEMP-induced male reproductive cells apoptosis via scavenging ROS حسب Long Ma (133810)

"…NEMP exposure induced damage to both GC-1 and TM-3 cells, resulting in decreased cell viability and increased apoptosis rates. …"

Image 3_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg حسب Kaisong Huang (5412626)

"…However, the precise role of IL-26 in the host immune defense against Mtb infections and intracellular killing remains largely unexplored. In this study, we observed significantly elevated IL-26 mRNA expression in peripheral blood mononuclear cells of active-TB patients compared to healthy individuals. …"

Image 1_Interleukin-26 expression in tuberculosis disease and its regulatory effect in macrophage polarization and intracellular elimination of Mycobacterium tuberculosis.jpeg حسب Kaisong Huang (5412626)

"…However, the precise role of IL-26 in the host immune defense against Mtb infections and intracellular killing remains largely unexplored. In this study, we observed significantly elevated IL-26 mRNA expression in peripheral blood mononuclear cells of active-TB patients compared to healthy individuals. …"

<b>Data used for analyses in the manuscript 'Sleep Regularity and Duration are Associated with Depression Severity in a Nationally Representative United States Sample'</b> حسب Katherine Maki (7445153)

"…</p><p dir="ltr"><b>Results: </b>Among participants (n=7297), we found associations between sleep-associated variables and SRI, with increased daytime sleep being the strongest correlate of decreased SRI. …"

Table 1_Association between red blood cell distribution width and encephalitis based on the pediatric intensive care unit database: a cross-sectional study.docx حسب Weichao He (16832265)

"…Multivariate regression models revealed that encephalitis in Chinese children was significantly decreased by 18% with 1% increase in RDW after adjusting for all covariates (Adjusted OR = 0.82, 95% CI: 0.73–0.92). …"

Data Sheet 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx حسب Lili Zhou (265076)

"…Cellular experiments further investigated the expression of cholesterol metabolism-related proteins and the effect of the cholesterol-depleting agent Methyl-β-cyclodextrin (MβCD) on DLBCL cells.</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …"

Table 5_Epizootic shell disease induces systemic transcriptomic shifts in Homarus americanus, characterized by increased shell degradation and impaired energy metabolism across tis... حسب Minseo Kim (773205)

"…The hepatopancreas showed decreased expression of hemocyanin genes, which play key roles in oxygen transport and immune defense in crustaceans. …"

Data Sheet 1_Global, regional, and national trends in the incidence of pneumoconiosis among populations aged 20 and above from 1990 to 2021.docx حسب Qiyun Cheng (22074758)

"…Utilizing data from the Global Burden of Disease (GBD) 2021, we have updated the epidemiological trends of pneumoconiosis.…"

Data Sheet 1_miR-223 alleviates DSS-induced colitis by prompting macrophage M2 polarization through PPAR-γ/FOXO1 signaling.pdf حسب Juanjuan Zhang (432819)

"…</p>Results<p>Histopathological analysis showed that miR-223 agomir significantly attenuated DSS-induced colon damage. Proinflammatory cytokines (TNF-α, IL-1β, IL-6) increased in DSS mice, while anti-inflammatory IL-10 decreased—trends reversed by miR-223 supplementation at mRNA/protein levels. …"

Table1_SMAD4 enhances the cytotoxic efficacy of human NK cells against colorectal cancer cells via the m6A reader YTHDF2.docx حسب Xinxin Li (281237)

"…Furthermore, we observed that enforced upregulation of SMAD4 resulted in enhanced cytotoxicity of NK cells towards CRC cells. …"

Image 2_Trends in adolescent pertussis burden: a systematic analysis from 1990 to 2021 in global, regional, and national within the global burden of disease study 2021, with foreca... حسب Huihui Zhu (4483621)

"…However, in Central Sub-Saharan Africa, the number of prevalence cases, incidence cases, deaths, and DALYs have increased, while these values have significantly decreased among adolescents in the other 20 GBD regions. …"

Table 1_RPL41 inhibits the proliferation and migration of retinoblastoma through the ARL5B-associated lysosomal trafficking.xlsx حسب Ye Li (290115)

"…ARL5B expression was significantly downregulated in treated Y79 and Weri-RB1 cells. …"

Image 1_Association between red blood cell distribution width and encephalitis based on the pediatric intensive care unit database: a cross-sectional study.tif حسب Weichao He (16832265)

"…Multivariate regression models revealed that encephalitis in Chinese children was significantly decreased by 18% with 1% increase in RDW after adjusting for all covariates (Adjusted OR = 0.82, 95% CI: 0.73–0.92). …"