Image 1_Cerebellar microstructural and functional connectivity changes in patients with neuromyelitis optica spectrum disorders and their correlation with cognitive function: a fem... by Yingyu Zhang (7846409)

“…</p>Results<p>Patients exhibited significant cerebellar alterations, including GMV reduction in bilateral lobules VI/VIII and the vermis, decreased fractional anisotropy in Crus I, and altered FC between Crus I and occipital/frontal regions. …”

Table 1_A study on the effects of modified sprint interval trainingon physical fitness test scores and the quantitative and dose-response relationships among Chinese male universit... by Guoyuan Huang (4262416)

“…</p>Results<p>The results showed significant improvements in key anaerobic capacity indicators after the 6-week intervention: Average Power (AP) increased from 77.4 ± 10.1 to 132.6 ± 21.1 (p < 0.01, Adjusted p < 0.03 ment, with a maximum effect size of 3.344), Peak Power (PP) increased from 102.9 ± 14.5 to 189.5 ± 28.8 (p < 0.01, Adjusted p < 0.02, maximum effect 3.790), and Time to Peak Power (TTP) decreased from 12.3 ± 3.3 to 9.5 ± 2.6 (p < 0.01), confirming that the intervention enhanced the participants' anaerobic capacity. …”

Image 1_Snowmelt seepage fluxes of dissolved organic matter in forest and grassland – a molecular-level case study from the Hainich Critical Zone Exploratory, Germany.pdf by Chen Huang (202847)

“…This study, conducted at the Hainich Critical Zone Exploratory in Germany, seeks to address a significant gap in understanding the molecular impacts of snowmelt-induced DOM flows and their ability to alter soil ecosystems rapidly. …”

Preliminary efficacy of eye movement desensitization and reprocessing for children aged 1.5–8 years with PTSD: a multiple baseline experimental design (<i>N</i> = 19) by Carlijn de Roos (8061239)

“…</p><p>The findings also show a significant reduction in emotional and behavioural problems as well as parenting stress.…”

Data Sheet 1_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

“…We used Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 to make a stable Danio rerio model of crim1 deficiency, generating zebrafish that were homozygous for a 2 basepair deletion, c.339_340delCT p.Leu112Leufs*, in crim1.…”

Data Sheet 1_Understanding the long-term interplay of SARS-CoV-2 immune and inflammatory responses with proteases in COVID-19 recovery: a longitudinal study.pdf by Natalia Ćwilichowska-Puślecka (21515129)

“…Key findings include a decreasing deregulatory effect on immune responses exerted by subsequent SARS-CoV-2 variants Alpha, Delta, and Omicron.…”

Data Sheet 1_Primary care and specialist physicians’ prescribing preferences for concurrent probiotic-antibiotic therapy: a multinational clinical practice survey across 13 countri... by Stephan R. Vavricka (8994197)

“…<p>Antibiotic-induced intestinal microbiota disruption represents a significant clinical concern, yet physician practices regarding concurrent probiotic supplementation remain poorly characterized across international healthcare systems. …”

Data Sheet 1_Tumor-associated MerTK promotes a pro-inflammatory microenvironment and enhances immune checkpoint inhibitor response in triple-negative breast cancer.docx by Bridget E. Crossman (18230326)

“…</p>Results<p>Overexpression of MerTK in TNBC syngeneic mouse models leads to a marked delay in tumor growth, coupled with significant increases in anti-tumor M1 macrophage, CD4+ T cell, active CD8+ T cell, active NK cell, and NKT cell populations. …”

Table1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and coloca... by Jingshuang Song (11340138)

“…</p>Results<p>Gene-predicted levels of ten proteins were associated with breast cancer risk. Decreased levels of CASP8, DDX58, CPNE1, ULK3, PARK7, and BTN2A1, as well as increased levels of TNFRSF9, TNXB, DNPH1, and TLR1, were linked to an elevated risk of breast cancer. …”

Image 2_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff by Peerapon Kiatkittikul (22801874)

“…[¹⁸F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”

Image 4_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff by Peerapon Kiatkittikul (22801874)

“…[¹⁸F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”

Table 1_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.docx by Peerapon Kiatkittikul (22801874)

“…[¹⁸F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”

Data_Sheet_1_Long-term phenobarbital treatment is effective in working-age patients with epilepsy in rural Northeast China: a 10-year follow-up study.docx by Rongxin Li (3552779)

“…The most commonly reported AEs were drowsiness (43.3%), dizziness (25.0%), and headaches (17.0%), most of which were mild and decreased over time. Age at enrollment was the only factor influencing withdrawal (hazard ratio = 0.984, 95% CI: 0.973–0.996, p = 0.010), with a substantial number of patients who withdrew (32.6%) relocating for work. …”

Image 3_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff by Peerapon Kiatkittikul (22801874)

“…[¹⁸F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”

Supplementary file 1_Association between changes in corrected anion gap and mortality among critically ill patients during ICU stay: a multicenter observational study.doc by Yanli Hou (6561536)

“…When analyzed categorically, the ΔcAG still exhibited a significant risk gradient across quartiles.</p>Conclusion<p>Further elevated cAG after ICU admission demonstrates a robust association with an increased mortality risk in critically ill patients. …”

Image 1_Automated radiosynthesis and clinical experience of [18F]SMBT-1 PET imaging for in vivo evaluation of reactive astrocyte in Parkinson's disease: a pilot study.tiff by Peerapon Kiatkittikul (22801874)

“…[¹⁸F]SMBT-1 is a promising novel radiotracer for in vivo evaluation of reactive astrogliosis.…”

DataSheet1_The effect of 12-week high-dose Colostrum Bovinum supplementation on immunological, hematological and biochemical markers in endurance athletes: a randomized crossover p... by Krzysztof Durkalec-Michalski (4691311)

“…</p>Results<p>At COL_POST visit the secretory IgA (SIgA) concentration in saliva was significantly higher at POST-EX and REC compared to REST (p<0.05). …”

Table 1_Global and regional burdens of opioid use disorder from 1990 to 2021, with future forecasts to 2050: a systematic analysis for the global burden of disease study 2021.docx by Juanzhao Cao (22651742)

Data Sheet 1_Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles.... by Ettore Silvagni (9576002)

“…Objective<p>The aim of this study was to comparatively assess the risk of cardiovascular events (CVEs) in rheumatoid arthritis (RA) patients treated with Janus kinase inhibitors (JAKis) or tumor necrosis factor inhibitors (TNFis) and to explore the interactions with patient profiles [including age, baseline cardiovascular (CV) risk, and frailty, which is a state of decreased physiological reserve, assessed using a validated frailty index (FI) for healthcare administrative databases (AHDs)].…”

Data Sheet 2_Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles.... by Ettore Silvagni (9576002)

“…Objective<p>The aim of this study was to comparatively assess the risk of cardiovascular events (CVEs) in rheumatoid arthritis (RA) patients treated with Janus kinase inhibitors (JAKis) or tumor necrosis factor inhibitors (TNFis) and to explore the interactions with patient profiles [including age, baseline cardiovascular (CV) risk, and frailty, which is a state of decreased physiological reserve, assessed using a validated frailty index (FI) for healthcare administrative databases (AHDs)].…”