Video1_One-year real-world experience with mavacamten and its physiologic effects on obstructive hypertrophic cardiomyopathy.mov حسب Daniel Seung Kim (19510291)

"…Moreover, in our center's experience, neither arrhythmia burden, nor contractility have worsened in the vast majority of patients: we note a clinically insignificant mean decrease in left ventricular ejection fraction (LVEF), with only two patients requiring temporary mavacamten discontinuance for LVEF < 50%. …"

pone.0331193.t003 - حسب Carol Kotliar (22351525)

"…The global cognitive score increased by 4.6 points (5%) in the intervention group compared to a decrease of 0.5 points in the control group (p < 0.001). …"

Baseline characteristics by group. حسب Carol Kotliar (22351525)

"…The global cognitive score increased by 4.6 points (5%) in the intervention group compared to a decrease of 0.5 points in the control group (p < 0.001). …"

Data Sheet 1_Dupilumab treatment has no effect on the nasal microbiome in patients with NSAID-exacerbated respiratory disease: a longitudinal pilot study.pdf حسب Tina Bartosik (12300785)

"…Dupilumab, a monoclonal antibody targeting the IL-4 receptor α chain, leads to symptom relief and reduction in nasal type 2 mediator levels. Here, we investigated the impact of dupilumab treatment on the composition and diversity of the nasal microbiome.…"

Beta cell function derived from routine clinical measures reports and predicts treatment response to immunotherapy in recent-onset type 1 diabetes. حسب Michelle So (400874)

"…Beta2 score, derived from fasting glucose, C-peptide, HbA1c and insulin dose at 12 weeks, was optimal for predicting QRS>0 following one year of treatment with baricitinib and the other immunotherapies (areas under receiver-operator curve 0.864 and 0.765 respectively). A 6.2% decrease in Beta2 score at week 12 predicted significant improvement in HbA1c (-0.6% or -6 mmol/mol) and insulin use (-0.26 units/kg/day) in combined data from the rituximab, abatacept and anti-thymocyte globulin trials.…"

Data Sheet 1_Pregnancy and contraceptive use among participants of childbearing potential in the HVTN 705 HIV vaccine trial in Southern Africa.docx حسب Pamela Mda (20390050)

"…Nevertheless, some pregnancies occur in almost all studies. We examined contraceptive use, pregnancy incidence, and the relationship between pregnancy and HIV seroconversion in one HIV vaccine trial.…"

Data Sheet 1_Impact of implementing a pediatric early warning system on outcomes in hematopoietic stem cell transplant units in South America and Europe.docx حسب Monica L. Quijano-Lievano (22808537)

"…There was a non-significant decrease in clinical deterioration event mortality post-PEWS implementation (24%, n = 17/71 vs. 15%, n = 22/150, p = 0.1335).…"

Comparative Analysis of Gut Microbiota in Collegiate Swimmers Following Changes in Exercise حسب Jarrad Hampton-Marcell (695263)

"…Peak training volume, measured as swimming distance, decreased significantly during the study period from 32.6 ± 4.8 km/wk to 11.3 ± 8.1 km/wk (ANOVA, p < 0.05); however, body composition showed no significant changes. …"

Table 1_Gender difference in the association between composite dietary antioxidant index and all-cause mortality.docx حسب Lanzhi Duan (15350413)

"…</p>Results<p>The study encompassed a sample of 15,651 individuals. The mean CDAI was 0.52 ± 6.06. The restricted cubic spline revealed that the hazard ratio (HR) of all-cause mortality decreased significantly with increasing CDAI. …"

Image 1_Evaluation of clopidogrel impact on canine platelet function using flow cytometry and thromboelastography platelet mapping.tif حسب Eunchae Yoon (21487805)

"…Flow cytometry confirmed the marked inhibition of platelet activation, with significant decreases in the percentage of CD62P positive platelets and the mean fluorescence intensity under ADP and epinephrine stimulation (p < 0.05). …"

Table 1_Single and consecutive 10-day remote ischemic preconditioning modify physical performance, post-exercise exerkine levels, and inflammation.docx حسب Magdalena Kochanowicz (20153682)

"…Similarly, a significant 15.5% (p < 0.05) decrease in the IL-6 concentration 120 min after the WAnT was observed only in the consecutive 10-day RIPC protocol, as well as a 12.2% (p < 0.01) increase in oncostatin M 60 min after the WAnT.…"

Table 1_Uncaria tomentosa extract exerts antimicrobial activity against boar seminal bacteria and influences sperm resilience under different conditions.xlsx حسب Maria Scaringi (18815462)

"…During semen storage, the extract did not show any cytotoxicity, and mean values of some sperm parameters were higher than the control group, although not significant (p > 0.05). …"

Table 1_Associations between the Dietary Inflammatory Index and depression among pregnant and postpartum women: analysis of NHANES 2005–2018.docx حسب Jian Qiao (26659)

"…Diets with very high proinflammatory potential were linked to significantly increased odds of perinatal depression, whereas more anti-inflammatory diets did not result in a further decrease in depression risk below that threshold. …"

Data from: Decade-long bird trends in China: Stable species richness but increasing biotic homogenization حسب Jiekun He (20964269)

"…We found that species richness remained stable over 10 years, with no directional trend at 84.5% of sites and a small mean effect size (Zr = 0.102, 95% CI = [-0.012; 0.216]). …"

Data Sheet 1_Exploring long COVID in pediatric patients: clinical insights from a long COVID clinic.docx حسب Dina Kamel (22434430)

"…Overall symptom burden decreased significantly over time (p < 0.001). Vaccination status at baseline was not associated with difference in symptom duration on initial presentation (p = 0.4). …"

Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction حسب Yangyi Huang (11859382)

"…</p> <p>The EOZ continued decreasing following hyperopic KLEx. A larger TZ and POZ would result in a larger postoperative EOZ.…"

Data Sheet 1_Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.pdf حسب Yihong Yang (557831)

"…</p>Results<p>In our study, we have successfully established the mouse HIRI injury model, and the liver function indicators such as ALT, AST and LDH were significantly increased in the HIRI model group, while SEN pretreatment could lead to a significant decrease in these enzymatic activities, especially perfusion at 6 h. …"

Table 1_Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.xls حسب Yihong Yang (557831)

"…</p>Results<p>In our study, we have successfully established the mouse HIRI injury model, and the liver function indicators such as ALT, AST and LDH were significantly increased in the HIRI model group, while SEN pretreatment could lead to a significant decrease in these enzymatic activities, especially perfusion at 6 h. …"

Supplementary Material for: Exploring the Link between Hypertension and Cerebral White Matter Changes in Chronic Kidney Disease حسب figshare admin karger (2628495)

"…Further study is needed to evaluate adequate blood pressure control to decrease the risk of brain damage in CKD patients.…"

Table 1_Serum symmetric dimethylarginine concentrations in enalapril- or telmisartan-treated dogs with proteinuric chronic kidney disease.xlsx حسب Amirah Nasr (20394893)

"…In dogs co-treated with amlodipine, a significant absolute decrease in mean SDMA (−2.29 μg/dL; p = 0.026) occurred at days 7 and 30, while mean creatinine was unchanged and mean SUN increased.…"