Beta cell function derived from routine clinical measures reports and predicts treatment response to immunotherapy in recent-onset type 1 diabetes. by Michelle So (400874)

“…Beta2 score, derived from fasting glucose, C-peptide, HbA1c and insulin dose at 12 weeks, was optimal for predicting QRS>0 following one year of treatment with baricitinib and the other immunotherapies (areas under receiver-operator curve 0.864 and 0.765 respectively). A 6.2% decrease in Beta2 score at week 12 predicted significant improvement in HbA1c (-0.6% or -6 mmol/mol) and insulin use (-0.26 units/kg/day) in combined data from the rituximab, abatacept and anti-thymocyte globulin trials.…”

Data Sheet 1_Impact of implementing a pediatric early warning system on outcomes in hematopoietic stem cell transplant units in South America and Europe.docx by Monica L. Quijano-Lievano (22808537)

“…There was a non-significant decrease in clinical deterioration event mortality post-PEWS implementation (24%, n = 17/71 vs. 15%, n = 22/150, p = 0.1335).…”

Comparative Analysis of Gut Microbiota in Collegiate Swimmers Following Changes in Exercise by Jarrad Hampton-Marcell (695263)

“…Peak training volume, measured as swimming distance, decreased significantly during the study period from 32.6 ± 4.8 km/wk to 11.3 ± 8.1 km/wk (ANOVA, p < 0.05); however, body composition showed no significant changes. …”

Changes in the effective optical zone following hyperopic keratorefractive lenticule extraction by Yangyi Huang (11859382)

“…</p> <p>The EOZ continued decreasing following hyperopic KLEx. A larger TZ and POZ would result in a larger postoperative EOZ.…”

Data Sheet 1_Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.pdf by Yihong Yang (557831)

“…</p>Results<p>In our study, we have successfully established the mouse HIRI injury model, and the liver function indicators such as ALT, AST and LDH were significantly increased in the HIRI model group, while SEN pretreatment could lead to a significant decrease in these enzymatic activities, especially perfusion at 6 h. …”

Table 1_Sinensetin attenuates hepatic ischemia-reperfusion injury through suppressing GRP78/CHOP-mediated endoplasmic reticulum (ER) stress in mice.xls by Yihong Yang (557831)

“…</p>Results<p>In our study, we have successfully established the mouse HIRI injury model, and the liver function indicators such as ALT, AST and LDH were significantly increased in the HIRI model group, while SEN pretreatment could lead to a significant decrease in these enzymatic activities, especially perfusion at 6 h. …”

Supplementary Material for: Exploring the Link between Hypertension and Cerebral White Matter Changes in Chronic Kidney Disease by figshare admin karger (2628495)

“…Further study is needed to evaluate adequate blood pressure control to decrease the risk of brain damage in CKD patients.…”

Data Sheet 1_Distribution of different plant life forms on tropical islands: patterns and underlying mechanisms.docx by Chengfeng Yang (3333489)

“…Furthermore, the relative tree richness and abundance are predominant on larger, less isolated islands, whereas shrubs are more prevalent on smaller, more remote islands. …”

Fig 8 - by Shima Bahramizadeh-Sajadi (20391247)

“…Although ring category has a greater effect on these measures than the cross-sectional area, the area also affects the results: Increasing the cross-sectional area of the ring causes the cornea to flatten, resulting in a decrease in K_mean and axial length. The cornea also becomes thinner when larger rings are used and the contact pressure between the ring and the cornea increases. …”

Data_Sheet_1_Subthreshold amyloid deposition, cerebral small vessel disease, and functional brain network disruption in delayed cognitive decline after stroke.docx by Jae-Sung Lim (532986)

“…Decliners [defined by a decrease of ≥3 Mini-Mental State Examination (MMSE) points annually or an absolute drop of ≥5 points between evaluations, confirmed with detailed neuropsychological tests] were compared with age- and stroke severity-matched non-decliners. …”

Location of weather stations used in the study. by Maksim Khitrykau (20107936)

“…The average duration of frost and summer cold waves has decreased by 0.5–1.5 days, the average duration of strong thaws has increased by 1 day, while the changes in the duration of heat waves have been less significant. …”

Data Sheet 1_Interannual variability of the Barents Sea branch water in the northeastern part of the Barents Sea and the St. Anna Trough.pdf by Zinaida Zabudkina (14771266)

“…The observed warming of BSBW accompanied by its salinity decrease, which is observed during the last 15 years, could significantly affect thermohaline structure and circulation in the Arctic Ocean.…”

<b>Supporting data for ''The pathogenicity and pathogenic mechanism of SARS-CoV-2 Omicron''</b> by Bingjie Hu (10835565)

“…Further mechanistic investigations reveal that the Omicron subvariant is ineffective in using TMPRSS2 compared with ancestral SARS-CoV-2 (HKU-001a) and previous variants, which may contribute to its decreased replication in Calu3 and Caco2 cells. In K18-hACE2 transgenic mice, the replication capacity of the Omicron subvariant is significantly attenuated in both the upper and lower respiratory tracts of virus-infected animals when compared to that of the ancestral strain and Delta (B.1.617.2) variant, correlating with substantially ameliorated lung pathology. …”

A systematic review of the efficacy and safety of anti-amyloid beta monoclonal antibodies in treatment of Alzheimer’s disease by Akanksha Chhabra (71080)

“…Aducanumab resulted in a decrease of −0.39 (−22%). Bapineuzumab showed no significant benefit, with scores of 2.4 (2.8). …”

<b>Gene x environment interactions as drivers of lifespan variation in nematodes</b> by Justin Havird (2812975)

“…Both the genetic strains and phytochemicals were associated with mitochondrial function. We found significant effects of genetic background (although not always as precited from previous studies), chemical treatment, and their interactions (GxE) that explained variation in lifespan. …”

Table 4_Meta-analysis of the effects of exercise interventions on dialysis patients with cardiac function disorders.docx by Huizhen Liu (1596664)

“…</p>Conclusion<p>Exercise can significantly enhance LVEF and decrease LVMI in dialysis patients. …”

Table 5_Meta-analysis of the effects of exercise interventions on dialysis patients with cardiac function disorders.docx by Huizhen Liu (1596664)

“…</p>Conclusion<p>Exercise can significantly enhance LVEF and decrease LVMI in dialysis patients. …”

Table 3_Meta-analysis of the effects of exercise interventions on dialysis patients with cardiac function disorders.docx by Huizhen Liu (1596664)

“…</p>Conclusion<p>Exercise can significantly enhance LVEF and decrease LVMI in dialysis patients. …”

Table 1_Meta-analysis of the effects of exercise interventions on dialysis patients with cardiac function disorders.docx by Huizhen Liu (1596664)

“…</p>Conclusion<p>Exercise can significantly enhance LVEF and decrease LVMI in dialysis patients. …”

Table 2_Meta-analysis of the effects of exercise interventions on dialysis patients with cardiac function disorders.docx by Huizhen Liu (1596664)

“…</p>Conclusion<p>Exercise can significantly enhance LVEF and decrease LVMI in dialysis patients. …”