Data Sheet 1_Targeting the leptin receptor promotes MDA-MB-231 cells’ metabolic reprogramming and malignancy: the role of extracellular vesicles derived from obese adipose tissue.d... حسب Carol Costa Encarnação (21412730)

"…In addition to metabolic alterations, OB EVs also impacted mitochondrial dynamics. We observed an upregulation of fusion and fission markers and a redistribution of mitochondria toward the cell periphery, which supports migration. …"

Table 1_LpxR and PagL expression in live attenuated auxotrophic Pseudomonas aeruginosa vaccines modulates lipid A reactogenicity in vitro while preserving immunogenicity.docx حسب Miriam Moscoso (345679)

"…Introduction<p>Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen responsible for severe respiratory tract infections. We previously developed a live attenuated auxotrophic vaccine candidate, PAO1 ΔmurI, which conferred protection in murine infection models but exhibited significant reactogenicity when administered intranasally. …"

Image 3_Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.jpeg حسب Amy Fagan (17678004)

"…We measured pulmonary mechanics and the abundance and secretion characteristics of the major secreted mucin glycoproteins, mucin 5B (Muc5b) and mucin 5ac (Muc5ac).…"

Yeast strains used in this study. حسب Hilary T. Brewis (11798006)

"…To explore this possibility, we generated mRNA transcript profiles for wild-type, <i>htz1</i>Δ, <i>swr1</i>Δ, and <i>htz1</i>Δ<i>swr1</i>Δ mutants before and after exposure to hydroxyurea (HU), which induces DNA replication stress. …"

Data Sheet 1_Celecoxib prevents malignant progression of smoking-induced lung tumors via suppression of the COX-2/PGE2 signaling pathway in mice.pdf حسب Kaori Sakurai (1272567)

"…Introduction<p>Lung cancer is characterized by a poor prognosis and is a significant comorbidity of chronic obstructive pulmonary disease (COPD). …"

Image 1_Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study.jpeg حسب Khalaf Kridin (7523390)

"…Introduction<p>Chronic, non-communicable inflammatory diseases (CIDs) affect a large portion of the population, imposing a significant morbidity, encompassing a substantial mortality. …"

Data Sheet 1_Associations between obesity and arterial stiffness assessed by cardio-ankle vascular index in healthy children and adolescents.docx حسب Yuko Horikoshi (12202859)

"…In contrast, CAVI showed no significant correlation with blood pressure or body weight. …"

Data Sheet 1_Top motor and non-motor complaints in patients with Parkinson's disease.docx حسب José Fidel Baizabal-Carvallo (11416508)

"…Responses were divided into three tiers.</p>Results<p>We studied 230 consecutive patients with PD. There were 130 (56.5%) male patients, with the mean age at evaluation of 67.7 ± 11.06 years. …"

Identification of novel pathogenic mutations in <i>ATP6V0A4</i> associated with distal renal tubular acidosis and analysis of wild-type expression in glomerular disease حسب Yaru Jiang (17458815)

"…If untreated, it can result in a significant electrolyte imbalance and progressive chronic kidney disease (CKD). …"

Image 2_Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.jpeg حسب Amy Fagan (17678004)

"…We measured pulmonary mechanics and the abundance and secretion characteristics of the major secreted mucin glycoproteins, mucin 5B (Muc5b) and mucin 5ac (Muc5ac).…"

Table 1_Global, regional, and national anemia burden among women of reproductive age (15–49 years) from 1990 to 2021: an analysis of the Global Burden of Disease Study 2021.docx حسب Wenshuai Zheng (21641225)

"…Background<p>Anemia remains a significant global health challenge, disproportionately affecting women of reproductive age (WRA, 15 to 49 years) due to physiological and socioeconomic factors. …"

Table1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and coloca... حسب Jingshuang Song (11340138)

"…Therefore, we conducted a comprehensive proteome-wide Mendelian randomization (MR) study to identify novel biomarkers and potential therapeutic targets for breast cancer.…"

DataSheet1_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... حسب Jingshuang Song (11340138)

"…Therefore, we conducted a comprehensive proteome-wide Mendelian randomization (MR) study to identify novel biomarkers and potential therapeutic targets for breast cancer.…"

Data Sheet 1_Microbial dysbiosis in obstructive sleep apnea: a systematic review and meta-analysis.docx حسب Yang Guo (399435)

"…Background<p>The association between the microbiota and obstructive sleep apnea (OSA) remains understudied. In this study, we conducted a comprehensive systematic review and meta-analysis of studies investigating the diversity and relative abundance of microbiota in the gut, respiratory tracts and oral cavity of patients with OSA, aiming to provide an in-depth characterization of the microbial communities associated with OSA.…"

Image 1_Club cell-derived brain-derived neurotrophic factor regulates murine airway mechanics and mucin production in response to IL-13 in a sex-dependent manner.jpeg حسب Amy Fagan (17678004)

"…We measured pulmonary mechanics and the abundance and secretion characteristics of the major secreted mucin glycoproteins, mucin 5B (Muc5b) and mucin 5ac (Muc5ac).…"

Supplementary file 1_Integrating Drosophila and Vibrio fischeri models for toxicity evaluation: uncovering detoxification trends in psoralea Fructus-TCM formulations.docx حسب Cheng Zhang (70708)

"…Enzyme assays indicated a decreasing toxicity trend for ESP and SSP compared to PF, with significant changes observed in female flies. …"

The Type I JAKinib, ruxolitinib, promotes pJAK1 and pJAK2 phosphorylation in MSCs from salivary glands. حسب Ilya Gurevic (1326786)

"…At each time or dose of ruxolitinib, we harvested cells for protein and performed western blot for the indicated target. …"

DataSheet2_Identifying new biomarkers and potential therapeutic targets for breast cancer through the integration of human plasma proteomics: a Mendelian randomization study and co... حسب Jingshuang Song (11340138)

"…Therefore, we conducted a comprehensive proteome-wide Mendelian randomization (MR) study to identify novel biomarkers and potential therapeutic targets for breast cancer.…"

Data Sheet 1_Elevated Galectin-3 levels in the tumor microenvironment of ovarian cancer – implication of ROS mediated suppression of NK cell antitumor response via tumor-associated... حسب Veronika Karlsson (20457788)

"…In co-cultures with NK cells and K562 target cells, we observed that Galectin-3-induced production of reactive oxygen species in neutrophils resulted in decreased NK cell viability and lowered anti-tumor responses.…"

Supplementary Material for: Genetical predicted causal relationship between gut microbiota and different types of kidney diseases حسب figshare admin karger (2628495)

"…No significant pleiotropy or heterogeneity was identified. …"