Opportunistic analysis of clinically actionable DPYD gene variants in a germline testing cohort in India حسب Rajdeep Raha (22056304)

"…</p> <p>A total of 95 individuals (5.3%) carried at least one decreased or no function DPYD variant, indicating a significant prevalence of clinically actionable genotypes in this Indian cohort. …"

Data Sheet 1_The effects of acupoint catgut embedding therapy on anthropometric parameters and endocrine function in obese women: a systematic review and meta-analysis.pdf حسب Shuangqiu Li (8083634)

"…Hormonal changes included decreased LH and FSH and increased E2.</p>Conclusion<p>Our meta-analysis demonstrates that ACET significantly improves anthropometric parameters and endocrine function in obese women, though it does not significantly impact lipid metabolism or insulin resistance. …"

Table 1_Effect of Ebenatide on glycemic metabolism and body fat in patients with type 2 diabetes mellitus.docx حسب Cheng-lan Xu (21562694)

"…</p>Results<p>The Ebenatide group showed significantly lower in hemoglobin A1c (HbA1c), mean blood glucose (MBG), time above range (TAR) and standard deviation (SD), along with improvement of time in range (TIR) at Week 24 and Week 52 compared to baseline (P<0.05). …"

Table 1_Quantitative relationships between elastic modulus of rod and biomechanical properties of transforaminal lumbar interbody fusion: a finite element analysis.docx حسب Jie Li (15030)

"…</p>Results<p>Increasing rod-E decreased ROM of the fixed segment, mean strain of the bone grafts, and peak stresses on the cage and endplate, while increasing peak stress on the screw-rod system. …"

Data Sheet 1_Flaxseed intervention and reproductive endocrine profiles in patients with polycystic ovary syndrome: an open-labeled randomized controlled clinical trial.pdf حسب Zahra Najdgholami (21009269)

"…The LH/FSH ratio also significantly decreased in the flaxseed group (mean treatment effect: -0.341, 95% CI: -0.63 to -0.08, p = 0.031). …"

Differential mRNA expression of key metabolic and stress response genes in the <i>MYH7</i> Q315R mice. حسب Shinya Takarada (8655066)

"…Clustering maps show significant changes in RNA expression (p < 0.05) greater than twofold or less than −2.0-fold (A and C). …"

Table 1_Effect of a mindfulness-based cognitive behavior therapy intervention on occupational burnout among school teachers.docx حسب Netra Raj Paudel (20610806)

"…No significant differences between the arms were found in the post-test mean levels of EE, DP, and PA. …"

Image2_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

"…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …"

DataSheet1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer... حسب Huijing Ren (19986303)

"…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …"

Image1_Combined administration of catalpol, puerarin, gastrodin, and borneol modulates the Tlr4/Myd88/NF-κB signaling pathway and alleviates microglia inflammation in Alzheimer’s d... حسب Huijing Ren (19986303)

"…Interference with this pathway significantly influenced the therapeutic effects of CPGB in the 3D-NVU model. …"

Table 2_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx حسب Jiayue Zhang (7832669)

"…In terms of period effect, there were fluctuations across the countries. Although China is less affected by the cyclical effect, the overall burden is increased. …"

Table 4_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx حسب Jiayue Zhang (7832669)

"…In terms of period effect, there were fluctuations across the countries. Although China is less affected by the cyclical effect, the overall burden is increased. …"

Table 5_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx حسب Jiayue Zhang (7832669)

"…In terms of period effect, there were fluctuations across the countries. Although China is less affected by the cyclical effect, the overall burden is increased. …"

Image 2_A nomogram model to predict the high risk of lower live birth probability in young women undergoing the first IVF-ET cycle: a retrospective study.tif حسب Chang Liu (35901)

"…There were five indicators significantly related to the risk of obtaining less than 10 oocytes at one oocyte retrieval cycle, including age, antral follicle count (AFC), anti-Mullerian hormone (AMH), follicle-stimulating hormone (FSH), and FSH to luteinizing hormone ratio. …"

Trends and Disparities in Rates of Hypoglycemia Among Hospitalized Patients with Type II Diabetes حسب Paul A Heidenreich (13188712)

"…After adjustment for other patient characteristics, the youngest and oldest patients, and those hospitalized in earlier years (vs. 2022) had significantly higher rates of hypoglycemia. Black (adjusted odds ratio -aOR, 1.42 95% CI 1.36-1.49) or Hispanic patients (aOR 1.26 95% CI 1.17-1.35) had a greater risk of hypoglycemia compared with non-Hispanic White patients and women had borderline less hypoglycemia than men (aOR 0.95, 95% CI 0.89-1.00)</p><p dir="ltr">Conclusion: Inpatient hypoglycemia in the VA Health System has been declining though there are race, age and gender differences that remain unexplained. …"

Image 1_A nomogram model to predict the high risk of lower live birth probability in young women undergoing the first IVF-ET cycle: a retrospective study.jpeg حسب Chang Liu (35901)

"…There were five indicators significantly related to the risk of obtaining less than 10 oocytes at one oocyte retrieval cycle, including age, antral follicle count (AFC), anti-Mullerian hormone (AMH), follicle-stimulating hormone (FSH), and FSH to luteinizing hormone ratio. …"

Unpowered dust removal system field physical map. حسب Yuxuan Liu (349237)

"…Field tests confirmed that after implementing the improved dust removal system, the ambient air dust concentration decreased to less than 2 mg/m³, representing a reduction of approximately 92.02% compared to pre-transformation levels. …"

Data Sheet 2_Early boosting of p38 MAPK signaling pathway by lycorine hydrochloride potently inhibits PRRSV proliferation in primary and established cells.pdf حسب Lizhan Su (19936980)

"…Mechanistically, LH treatment induced a rapid up-regulation of p38 MAPK signaling pathway in both infected and uninfected cells, which enhanced the expressions of NLRP3 and Caspase-1 proteins, thereby promoting the conversion of pro-IL-1β to IL-1β, which led to decreased PRRSV replication. In summary, this study reveals that early boosting of p38 MAPK signaling pathway induced by LH treatment significantly suppresses PRRSV propagation, and LH has the potential to be used as a novel antiviral agent against PRRSV infections.…"

Data Sheet 1_Comparative hepatoprotective effects of AMK and PAMK via Nrf2 signaling in broiler breeders.pdf حسب Baili Lu (21192662)

"…Histopathological analysis revealed better-preserved liver structure and less inflammatory infiltration in PAMK-fed hens. …"

Scarless excision of an insertion sequence in the OmpK36 promoter restores meropenem susceptibility in a non-carbapenemase-producing <i>Klebsiella pneumoniae</i> حسب Yingying Du (5877701)

"…<p>Carbapenem-resistant <i>Klebsiella pneumoniae</i> (CRKP) poses a significant global health challenge due to its limited treatment options and high mortality rates. …"