Proteomics and Metabolomics Analyses Reveal a Dynamic Landscape of Coal Workers’ Pneumoconiosis: An Insight into Disease Progression حسب Yangyang Wei (436909)

"…Integrated analysis found that ABC transporters are a shared pathway among the three groups, and ABCD2 is involved in the ABC transporter pathway. …"

PIK3C3 promotes <i>Listeria monocytogenes</i> cell-to-cell spread in HT-29 cells through DMV escape. حسب Steven J. Rolland (21376879)

PIK3C3 promotes the resolution of VLPs into DMVs through formation of PtdIns(3)P at the protrusion/VLP membrane. حسب Steven J. Rolland (21376879)

PIK3C3 is not involved in the formation of PtdIns(3)P at the inner membrane of protrusions. حسب Steven J. Rolland (21376879)

DNM2 promotes <i>Shigella flexneri</i> cell-to-cell spread. حسب Steven J. Rolland (21376879)

PIK3C3 promotes <i>Shigella flexneri</i> cell-to-cell spread through resolution of VLPs into DMVs. حسب Steven J. Rolland (21376879)

PIK3C3 is required for efficient cell-to-cell spread <i>in vivo.</i> حسب Steven J. Rolland (21376879)

PIK3C3 promotes <i>Listeria monocytogenes</i> cell-to-cell spread in Caco-2 cells. حسب Steven J. Rolland (21376879)

PIK3C3 promotes <i>Shigella flexneri</i> cell-to-cell spread in Caco-2 cells. حسب Steven J. Rolland (21376879)

PIK3C3 promotes <i>Shigella flexneri</i> cell-to-cell spread in HT-29 cells. حسب Steven J. Rolland (21376879)

Representative Western blots for proteins from specific gene groups, nitric oxide production, and NETs formation. حسب Daniel R. Ambruso (12042605)

PbPP6 disruption impairs the cGMP-PKG-Ca²⁺ signaling pathway. حسب Yonghui Feng (12227596)

The sexual stage phenotype of <i>pbpp6</i> gene knockout clones. حسب Yonghui Feng (12227596)

Flow cytometry measurement of CD11b, F-actin expression and content, and MHC Class II antigen expression of neutrophils from patients with CGD. حسب Daniel R. Ambruso (12042605)

Phenotype analysis of PbPP6-GFP parasites. حسب Yonghui Feng (12227596)

Sequence composition analysis identifies distinct A + U and C + G base frequencies within subregions of mRNA transcripts – with effects on protein coding potential. حسب Benjamin S. Pickard (21276556)

Frequency trajectories of iSNVs that fluctuated (Top) and their positions on the genome (Bottom) (patients A-I). حسب Lele Zhao (532080)

Addressing Imbalanced Classification Problems in Drug Discovery and Development Using Random Forest, Support Vector Machine, AutoGluon-Tabular, and H2O AutoML حسب Ayush Garg (21090944)

"…The important findings of our studies are as follows: (i) there is no effect of threshold optimization on ranking metrics such as AUC and AUPR, but AUC and AUPR get affected by class-weighting and SMOTTomek; (ii) for ML methods RF and SVM, significant percentage improvement up to 375, 33.33, and 450 over all the data sets can be achieved, respectively, for F1 score, MCC, and balanced accuracy, which are suitable for performance evaluation of imbalanced data sets; (iii) for AutoML libraries AutoGluon-Tabular and H2O AutoML, significant percentage improvement up to 383.33, 37.25, and 533.33 over all the data sets can be achieved, respectively, for F1 score, MCC, and balanced accuracy; (iv) the general pattern of percentage improvement in balanced accuracy is that the percentage improvement increases when the class ratio is systematically decreased from 0.5 to 0.1; in the case of F1 score and MCC, maximum improvement is achieved at the class ratio of 0.3; (v) for both ML and AutoML with balancing, it is observed that any individual class-balancing technique does not outperform all other methods on a significantly higher number of data sets based on F1 score; (vi) the three external balancing techniques combined outperformed the internal balancing methods of the ML and AutoML; (vii) AutoML tools perform as good as the ML models and in some cases perform even better for handling imbalanced classification when applied with imbalance handling techniques. …"

Various stereological parameters characterizing lung parenchyma and AEII before, during and after alveolarization as well as in adults. حسب Julia Hüttmann (22656283)

"…PLoS One. 2024 Mar 14;19(3):e029. b) The total number of alveolar epithelial cells type II (N(AEII, lung)) shows a significant increase after the end of bulk alveolarization and in adults compared to 3 days old rats. c) During alveolarization the number of AEII per mm² alveolar surface (N(AEII, lung)/S(alveoli, lung)) decreases continuously reaching the significant lowest values in adults. d) The number of AEII related to lung volume decreases continuously during alveolarization. …"

PRMT5 regulates alternative splicing landscape under hypoxia. حسب Srinivas Abhishek Mutnuru (22513457)

"…<p><b>A)</b> Pie chart showing distribution of different types of significant AS events (FDR < 0.05) in shCTRL vs. shPRMT5 MDA-MB-231 cells under hypoxia. …"