Roxadustat has risks of reversible central hypothyroidism in patients undergoing hemodialysis: a single-center retrospective cohort study by Emiko Otsuka (7519313)

“…Here, we retrospectively analyzed thyroid-stimulating hormone (TSH), free thyroxine (FT4), and free triiodothyronine (FT3) levels in 51 patients (mean age: 72.3 ± 10.7 years; 58.8% male) undergoing hemodialysis before, during, and after halting roxadustat treatment. TSH levels were significantly decreased from a median of 2.46 (interquartile range:1.60–4.51) mU/L before roxadustat treatment to 1.36 (0.72–2.41) mU/L during treatment (<i>p</i> < 0.001), and improved to 2.56 (1.78–4.63) mU/L after halting roxadustat (<i>p</i> < 0.001). …”

MST1 upregulates CD36 expression via PPARγ. by Jianyang Li (461703)

Table 1_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx by Luana Pulvirenti (2925741)

“…Introduction<p>Ocimum basilicum L. (basil) is a widely used aromatic plant with recognized functional properties, largely attributed to its rich profile of bioactive secondary metabolites. …”

Table 2_Effects of photoperiod on phytochemical profiles of four Ocimum basilicum genotypes in a hydroponic climate chamber.docx by Luana Pulvirenti (2925741)

“…Introduction<p>Ocimum basilicum L. (basil) is a widely used aromatic plant with recognized functional properties, largely attributed to its rich profile of bioactive secondary metabolites. …”

Data Sheet 1_OSH45, a homeobox transcription factor, coordinates low-phosphate adaptation in rice.pdf by Hong Lu (58784)

“…Subcellular localization assays indicated that OSH45 is a nuclear localized protein. OSH45 overexpression transgenic plants exhibited enhanced low-Pi tolerance, characterized by significantly higher Pi concentrations and increased shoot and root biomass compared to wild type (WT) under Pi-limited conditions. …”

Table 2_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx by Yi Shen (152956)

“…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …”

Table 1_Association of cardiorespiratory fitness with phenotypic age in younger population: a study based on the NHANES database.docx by Yi Shen (152956)

“…</p>Results<p>In the multivariable logistical regression analysis, maintenance of CRF was significantly and inversely associated with PAA, demonstrating a decreased risk of 42% in the high CRF group [OR (95% CI): 0.58 (0.36, 0.96), p = 0.033]. …”

Table 1_Association between telomere length and idiopathic normal pressure hydrocephalus: a Mendelian randomization study.docx by Feng Yang (132135)

“…</p>Results<p>Genetically determined longer telomere length was significantly associated with decreased risk of iNPH (OR = 0.44, 95% CI 0.24–0.80; p = 0.008). …”

Data Sheet 1_Oral immunotherapy for cow’s milk allergy in children: a systematic review and meta-analysis.docx by Yan Wang (15435)

“…Tolerance threshold at oral food challenges (OFC) increased following oral immunotherapy compared with a standard mean difference (SMD) of 3.58 (2.82–4.33). …”

Table 1_Association between DASH diet and metabolic syndrome in US adults: a cross-sectional study.xlsx by Jianing Liu (140090)

“…Subsequently, we discovered that DASH levels are significantly negatively correlated with waist circumference (WC), fasting plasma glucose (FPG), triglycerides (TG), and systolic blood pressure (SBP), while exhibiting a positive correlation with high-density lipoprotein cholesterol (HDL-C) through RCS curves and linear regression.…”

Data Sheet 1_Efficacy of Schisandra chinensis in liver injury: a systematic review and preclinical meta-analysis.docx by Bo-Hao Huang (18608359)

“…Schisandra chinensis, a traditional Chinese medicinal herb with a history of use spanning over 2,000 years, exhibits significant hepatoprotective, antioxidant, anti-inflammatory, and anti-apoptotic effects. …”

Table 2_Association between DASH diet and metabolic syndrome in US adults: a cross-sectional study.xlsx by Jianing Liu (140090)

“…Subsequently, we discovered that DASH levels are significantly negatively correlated with waist circumference (WC), fasting plasma glucose (FPG), triglycerides (TG), and systolic blood pressure (SBP), while exhibiting a positive correlation with high-density lipoprotein cholesterol (HDL-C) through RCS curves and linear regression.…”

Table1_Variation of leaf shape with tree size: a case study using Camptotheca acuminata Decne.xlsx by Ke He (331344)

“…<p>The Montgomery equation (ME) assumes that leaf area (A) is proportional to the product of leaf length (L) and width (W). …”

ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer by Ana García-García (17779885)

“…Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease, marked by a survival rate of only 12%. …”

Data Sheet 1_Cholesterol metabolic reprogramming drives the onset of DLBCL and represents a promising therapeutic target.docx by Lili Zhou (265076)

“…</p>Results<p>We confirmed significant alterations in metabolic markers (such as TC and ApoA1) between the healthy control group and patients, which were significantly associated with patient prognosis and overall OS. …”

Kaplan-Meier survival analysis comparing patients admitted before or during the COVID-19 period. by Rajkumar Rajendram (22505442)

MST1was downregulated in macrophages from fibrotic livers of <i>S</i>. <i>japonicum</i>-infected mice and SEA-treated RAW264.7 cells. by Jianyang Li (461703)

PCAIs induce apoptosis in NCI-H23 cells. by Matthew D. Gregory (19929096)

Fig 8 - by Maryam Banar (3220221)

Table 2_Tofacitinib extends survival in a mouse model of ALS through NK cell-independent mechanisms.xlsx by Lillia A. Baird (10575941)

“…Tofacitinib, an FDA-approved janus kinase (Jak) and signal transducer and activator (STAT) pathway inhibitor, reduces NK cytotoxicity and decreases overall levels in peripheral blood and may represent a potential ALS therapy. …”