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largest decrease » larger decrease (Expand Search), marked decrease (Expand Search)
less decrease » mean decrease (Expand Search), levels decreased (Expand Search)
teer decrease » mean decrease (Expand Search), greater decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
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2661
Data Sheet 4_N6-methyladenosine RNA landscape in the aged mouse hearts.pdf
Published 2025“…</p>Results<p>The overall m6A level remained constant; however, the expression of the methyltransferase METTL14 and the demethyltransferase FTO were significantly upregulated in aged hearts. Knockdown of METTL14 alleviated H<sub>2</sub>O<sub>2</sub>-induced senescence phenotypes, as reflected by a reduction in the number of SA-β-gal positive cells and a decrease in p21 expression. …”
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2662
Table 3_Effect of acarbose and vildagliptin on plasma trimethylamine N-oxide levels in patients with type 2 diabetes mellitus: a 6-month, two-arm randomized controlled trial.docx
Published 2025“…Intragroup analysis indicated a significant decrease in TMAO levels at 6 months compared with baseline (adjusted p<0.05). …”
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2663
Table 2_Effect of acarbose and vildagliptin on plasma trimethylamine N-oxide levels in patients with type 2 diabetes mellitus: a 6-month, two-arm randomized controlled trial.docx
Published 2025“…Intragroup analysis indicated a significant decrease in TMAO levels at 6 months compared with baseline (adjusted p<0.05). …”
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2664
The Enzyme Effect: Broadening the Horizon of MS Optimization to Nontryptic Digestion in Proteomics
Published 2025“…We analyzed peptide scores for thousands of peptides and determined optimal collision energy (CE) values. …”
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2665
Image 1_One-year post lockdown trajectories of mental health and impact of COVID-19 lockdown-related factors.png
Published 2025“…</p>Results<p>Our analysis revealed a significant decrease in the proportion of individuals experiencing poor mental health (elevated GAD-7 or PHQ-9 > 4) from lockdown period to 1 month and 6 months post-lockdown. …”
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2666
Table 1_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx
Published 2025“…</p>Results<p>Seven patients (14.5%) reduced LSM by over 50%. We found 47 significant differentially expressed (SDE) genes associated with reaching an LSMred>50% after achieving HCV eradication, 42 upregulated and 5 downregulated in the LSMred>50% group. …”
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2667
Data Sheet 1_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx
Published 2025“…</p>Results<p>Seven patients (14.5%) reduced LSM by over 50%. We found 47 significant differentially expressed (SDE) genes associated with reaching an LSMred>50% after achieving HCV eradication, 42 upregulated and 5 downregulated in the LSMred>50% group. …”
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2668
Supplementary Material for: Effect of frail phenotype on cardiorenal risk and healthcare utilization in older patients with chronic kidney disease
Published 2024“…Methods We conducted a prospective cohort enrolling patients ≥ 75 years with a stable estimated glomerular filtration rate (eGFR) < 60 mL/min/1.73 m2. …”
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2669
Table 2_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx
Published 2025“…</p>Results<p>Seven patients (14.5%) reduced LSM by over 50%. We found 47 significant differentially expressed (SDE) genes associated with reaching an LSMred>50% after achieving HCV eradication, 42 upregulated and 5 downregulated in the LSMred>50% group. …”
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2670
Regioisomeric Engineering for Multicharge and Spin Stabilization in Two-Electron Organic Catholytes
Published 2025“…Through a systematic study of regioisomers of near-planar aromatic cyclic triindoles and nonplanar nonaromatic cyclic tetraindoles, we demonstrate that this regioisomeric engineering strategy significantly enhances the H-cell cycling stability in the above two new classes of 2e<sup>–</sup> catholytes, even when current strategies failed to stabilize the multicharged species. …”
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2671
Table 4_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx
Published 2025“…</p>Results<p>Seven patients (14.5%) reduced LSM by over 50%. We found 47 significant differentially expressed (SDE) genes associated with reaching an LSMred>50% after achieving HCV eradication, 42 upregulated and 5 downregulated in the LSMred>50% group. …”
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2672
Table 3_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.docx
Published 2025“…</p>Results<p>Seven patients (14.5%) reduced LSM by over 50%. We found 47 significant differentially expressed (SDE) genes associated with reaching an LSMred>50% after achieving HCV eradication, 42 upregulated and 5 downregulated in the LSMred>50% group. …”
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2673
Image 1_PBMCs gene expression predicts liver fibrosis regression after successful HCV therapy in HIV/HCV-coinfected patients.pdf
Published 2025“…</p>Results<p>Seven patients (14.5%) reduced LSM by over 50%. We found 47 significant differentially expressed (SDE) genes associated with reaching an LSMred>50% after achieving HCV eradication, 42 upregulated and 5 downregulated in the LSMred>50% group. …”
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2674
Data Sheet 1_Groundwater stress in Europe—assessing uncertainties in future groundwater discharge alterations due to water abstractions and climate change.docx
Published 2024“…Groundwater stress is defined as any alteration in GWD since ecosystems are adapted to an equilibrium state. Focusing on decreasing GWD, which is generally more harmful than increasing GWD, we quantified the future GWSI in Europe by integrating scenarios of GWR and GWA in 2070–2099. …”
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2675
Image 2_One-year post lockdown trajectories of mental health and impact of COVID-19 lockdown-related factors.jpeg
Published 2025“…</p>Results<p>Our analysis revealed a significant decrease in the proportion of individuals experiencing poor mental health (elevated GAD-7 or PHQ-9 > 4) from lockdown period to 1 month and 6 months post-lockdown. …”
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2676
Data Sheet 1_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.pdf
Published 2025“…In cell experiments, we found that FX1 decreased secretion of pro-inflammatory factors by macrophages and increased expression of tight junction proteins in Caco2 cells after co-culture.…”
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2677
Restriction of mitochondrial oxidation of glutamine or fatty acids enhances intracellular growth of <i>Mycobacterium abscessus</i> in macrophages
Published 2025“…R-type Mab infections exhibited a marked decrease in glutamine reliance but enhanced metabolic flexibility and capacity. …”
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2678
The efficacy of colchicine compared to placebo for preventing ischemic stroke among individuals with established atherosclerotic cardiovascular diseases: a systematic review and me...
Published 2024“…Colchicine significantly decreased the risk of ischemic stroke (relative risk (RR) 0.85, 95% confidence interval (CI) (0.72, 0.99), I<sup>2</sup>=2.92%) among those with established atherosclerotic cardiovascular diseases. …”
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2679
Table 6_Quantitative proteomic analysis reveals potential serum diagnostic markers for colorectal adenoma.xlsx
Published 2025“…We propose FLNA as a potential biomarker for the diagnosis of colorectal adenomas. …”
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2680
Table 1_Inhibitior of Bcl6 by FX1 protects DSS induced colitis mice through anti-inflammatory effects.docx
Published 2025“…In cell experiments, we found that FX1 decreased secretion of pro-inflammatory factors by macrophages and increased expression of tight junction proteins in Caco2 cells after co-culture.…”