Image 3_Disruption of CDK5 regulatory subunit 1, p35, limits immunosuppressive M2 macrophages while maintaining functional M1 macrophages.tiff by Juliana R. Zampieri (22261441)

“…The absence of p35 significantly increased glycolysis during M1 polarization, while it also enhanced mitochondrial oxidative phosphorylation in the context of M2 polarization. …”

Supplementary Material for: The impact of left ventricular structure and function on mortality in patients with aortic valve infective endocarditis treated with aortic valve replac... by figshare admin karger (2628495)

“…The mean LVEF was 54±11% preoperatively, decreasing to 51±11% postoperatively. The mean baseline LVEDd was 5.8±0.9 cm in males and 5.0±0.9 cm in females (p<0.001), decreasing to 5.2±0.9 cm in males and 4.7±0.6 cm in females after surgery (p=0.006). …”

Table 1_Integrated gut microbiota and metabolomic profiling reveals key associations between amino acid levels and gut microbial composition in patients with obesity.docx by Musen Qi (22489075)

“…Metabolomic analysis revealed that in patients with obesity, the abundance of carnosine (log2FC = 1.16, FDR = 0.0016, VIP = 0.707), creatinine (log2FC = 0.21, FDR = 0.0009, VIP = 2.02), and cystine (log2FC = 0.55, FDR = 0.009, VIP = 1.47) was significantly increased compared with that in the controls; in contrast, that of ornithine (log2FC = −0.59, FDR = 0.0009, VIP = 1.19), citrulline (log2FC = −0.59, FDR = 0.0003, VIP = 0.707), glycine (log2FC = −0.54, FDR = 0.0003, VIP = 1.41), and serine (log2FC = −0.38, FDR = 0.0019, VIP = 1.62) was significantly decreased. …”

Data from: Population structure varies among four western North American bumble bee species by Elizabeth Sakulich (22077908)

“…Although we expected range-wide genetic differentiation for species with more narrow niche requirements, we found evidence of this differentiation for all four study species, with western populations experiencing significant genetic structure relative to inland populations. …”

Participants baseline characteristics. by Shenghang Wang (21213000)

“…</p><p>Methods</p><p>In this paper, we constructed MMF device using neodymium-iron-boron (NdFeB) materials. …”

Flowchart of the clinical trial. by Shenghang Wang (21213000)

“…</p><p>Methods</p><p>In this paper, we constructed MMF device using neodymium-iron-boron (NdFeB) materials. …”

Data Sheet 1_Post-COVID syndrome patients show reduced anti-Spike antibodies compared to COVID-recovered controls, but enhanced IgG4/IgG1 switch after the third vaccine dose.pdf by Nineth Rossi (22355524)

“…Initially, we established the risk factors and the evolution of symptoms. …”

Validation of the optimum formula. by Randa Mohammed Zaki (21637175)

“…The validation process on the optimized formula demonstrated that the variation from the predicted responses was less than 5%. The DSC and XRD studies revealed that AXT was entrapped within the bilosomal vesicles. …”

Data Sheet 1_Analyzing patterns of change in the orchid flora of Britain and Ireland with correlated environmental variability.pdf by Martha Charitonidou (798109)

“…</p>Methods<p>We use hypothesis tests for trends in occupancy for each orchid species, asking if there is significant evidence of change that cannot be attributed to natural processes. …”

Image 1_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Conversely, a stimulator of lysosome acidification/function, C381, decreased HLA-I expression. Lastly, we showed that in the presence of islet cells with defective autophagy, there is enhanced BDC2.5 T cell activation.…”

Image 3_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Conversely, a stimulator of lysosome acidification/function, C381, decreased HLA-I expression. Lastly, we showed that in the presence of islet cells with defective autophagy, there is enhanced BDC2.5 T cell activation.…”

Image 4_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tif by Matthew C. Austin (20633168)

“…Conversely, a stimulator of lysosome acidification/function, C381, decreased HLA-I expression. Lastly, we showed that in the presence of islet cells with defective autophagy, there is enhanced BDC2.5 T cell activation.…”

Image 2_Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.tiff by Matthew C. Austin (20633168)

“…Conversely, a stimulator of lysosome acidification/function, C381, decreased HLA-I expression. Lastly, we showed that in the presence of islet cells with defective autophagy, there is enhanced BDC2.5 T cell activation.…”

Antioxidants gene expressions in two tissues suspected to be involved in Decompression Sickness (DCS) triggering, in DCS resistant rats_Data by Emmanuel Dugrenot (18447504)

“…At the opposite, in the liver, we observed a decreased expression in both group of genes (except for <i>Pgc1α</i>), related to a selection effect.…”

Table 1_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.docx by Paolo Romania (399007)

“…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …”

Image 3_A genome-wide shRNA screen uncovers a novel potential ligand for NK cell activating receptors.jpg by Paolo Romania (399007)

“…PLAC1 and DSG2 expression in healthy tissues and NK cells was obtained from the HPA database and a GEO dataset.</p>Results<p>We identified ten candidate genes whose downregulation in K562 cells decreased NK cell-mediated cytotoxicity to levels comparable to silencing the MICA gene. …”

Table 2_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.xlsx by Chao-Chao Chen (21090215)

“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”

Image 4_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an... by Chao Song (379006)

“…This meta-analysis aims to compare the antitumor effectiveness and safety profiles of PIBC with PIC.</p>Methods<p>We systematically searched six databases to identify eligible RCTs. …”

Table 3_PD-1/PD-L1 inhibitors plus bevacizumab plus chemotherapy versus PD-1/PD-L1 inhibitors plus chemotherapy for advanced non-small cell lung cancer: a phase 3 RCT based meta-an... by Chao Song (379006)

“…This meta-analysis aims to compare the antitumor effectiveness and safety profiles of PIBC with PIC.</p>Methods<p>We systematically searched six databases to identify eligible RCTs. …”

Image 3_Relations between neurometabolism and clinical biomarkers in patients with metabolic disease.tiff by Chao-Chao Chen (21090215)

“…<p>The global prevalence of metabolic diseases, including hypertension, type 2 diabetes mellitus (T2DM), gout, and obesity, has significantly increased over the past two decades. The brain plays a central role in regulating both human behavior and metabolism. …”