Data Sheet 1_Cytosolic phospholipase A2 links tau pathology to insulin signaling impairment in Alzheimer’s disease.pdf by Faruk Hossen (20275670)

“…Specifically, we found significant decreases in insulin receptor-α (IR-α) and insulin receptor-β (IR-β) expression, along with increased levels of phospho-insulin receptor substrate 1 at Ser307 [p-IRS-1 (Ser307)] and decreased levels of p-IRS-1 (Tyr895), compared to wild-type (WT) mice. …”

Bad Estimation, Good Prediction: The Lasso in Dense Regimes by Andrea Bratsberg (22392452)

“…We prove that the prediction bound under this model in fact decreases with increasing number of predictors, and confirm this through simulation examples. …”

Image 4_Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome—a clinical pilot study.tiff by Øystein Fluge (200378)

“…DePaul Questionnaire-Short Form (DSQ-SF) symptom scores decreased from 72.3 to 43.1 (p = 0.002). In six responders, mean SF-36 PF increased from 32.2 to 78.3, and DSQ-SF score decreased from 71.1 to 24.3. …”

Data Sheet 2_Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome—a clinical pilot study.pdf by figshare admin frontiersin (4545187)

“…DePaul Questionnaire-Short Form (DSQ-SF) symptom scores decreased from 72.3 to 43.1 (p = 0.002). In six responders, mean SF-36 PF increased from 32.2 to 78.3, and DSQ-SF score decreased from 71.1 to 24.3. …”

Image 1_L1, a 3,3′-diindolylmethane-derivative, induced ER stress-mediated apoptosis and suppressed growth through the FLI1/AKT pathway in erythroleukemia HEL cells.tif by Yi Kuang (1873354)

“…Moreover, FLI1 is a crucial target for mediating cell differentiation, apoptosis, inflammation and displays abnormal expression in HEL cells. Here, we showed that the protein expression levels of FLI1 and AKT/p-AKT decreased with L1 treatment and that the RNA expressions of their downstream genes GATA1, TFRC, GYPA, CDKN1A and CDKN1B were also regulated by L1.…”

Data Sheet 1_Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome—a clinical pilot study.pdf by Øystein Fluge (200378)

“…DePaul Questionnaire-Short Form (DSQ-SF) symptom scores decreased from 72.3 to 43.1 (p = 0.002). In six responders, mean SF-36 PF increased from 32.2 to 78.3, and DSQ-SF score decreased from 71.1 to 24.3. …”

Image 2_Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome—a clinical pilot study.tiff by Øystein Fluge (200378)

“…DePaul Questionnaire-Short Form (DSQ-SF) symptom scores decreased from 72.3 to 43.1 (p = 0.002). In six responders, mean SF-36 PF increased from 32.2 to 78.3, and DSQ-SF score decreased from 71.1 to 24.3. …”

Image 3_Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome—a clinical pilot study.tiff by Øystein Fluge (200378)

“…DePaul Questionnaire-Short Form (DSQ-SF) symptom scores decreased from 72.3 to 43.1 (p = 0.002). In six responders, mean SF-36 PF increased from 32.2 to 78.3, and DSQ-SF score decreased from 71.1 to 24.3. …”

Table 1_Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome—a clinical pilot study.xlsx by Øystein Fluge (200378)

“…DePaul Questionnaire-Short Form (DSQ-SF) symptom scores decreased from 72.3 to 43.1 (p = 0.002). In six responders, mean SF-36 PF increased from 32.2 to 78.3, and DSQ-SF score decreased from 71.1 to 24.3. …”

Image 1_Plasma cell targeting with the anti-CD38 antibody daratumumab in myalgic encephalomyelitis/chronic fatigue syndrome—a clinical pilot study.tiff by Øystein Fluge (200378)

“…DePaul Questionnaire-Short Form (DSQ-SF) symptom scores decreased from 72.3 to 43.1 (p = 0.002). In six responders, mean SF-36 PF increased from 32.2 to 78.3, and DSQ-SF score decreased from 71.1 to 24.3. …”

Image 2_L1, a 3,3′-diindolylmethane-derivative, induced ER stress-mediated apoptosis and suppressed growth through the FLI1/AKT pathway in erythroleukemia HEL cells.tif by Yi Kuang (1873354)

“…Moreover, FLI1 is a crucial target for mediating cell differentiation, apoptosis, inflammation and displays abnormal expression in HEL cells. Here, we showed that the protein expression levels of FLI1 and AKT/p-AKT decreased with L1 treatment and that the RNA expressions of their downstream genes GATA1, TFRC, GYPA, CDKN1A and CDKN1B were also regulated by L1.…”

Complete dataset of loon productivity for Fuirst et al. by Matthew Fuirst (11236764)

“…While all regions showed long-term mean productivity rates at or above the threshold considered necessary for population stability (0.48 chicks fledged per territorial pair), we found significant declines in productivity (-0.17− -2.8% per year over 19−48 years) in seven regions, non-significant but downward trends in four others, and a non-significant increase in one region (Maine). …”

Data Sheet 1_Patient-centered modeling of the breast biopsy experience.pdf by Isabel Nieto-Alvarez (22425466)

“…Centering each individual's procedure time at her first local anesthesia (LA) revealed a significant (βt2p = 5.43e⁻⁰⁶) temporal pattern in anxiety, which increased until LA and decreased afterwards. …”

Table 2_Untargeted metabolic analysis in serum samples reveals metabolic signature in children with congenital heart failure on enalapril therapy.csv by N. J. L. Smeets (21188726)

“…Additionally, we investigated metabolic profiles in CHD patients and healthy controls.…”

Table 1_Untargeted metabolic analysis in serum samples reveals metabolic signature in children with congenital heart failure on enalapril therapy.csv by N. J. L. Smeets (21188726)

“…Additionally, we investigated metabolic profiles in CHD patients and healthy controls.…”

Data Sheet 1_Coordinated development of ecosystem services and human well-being is increasing in the Yellow River Basin, though some regions lag behind.docx by Menghao Yang (18527892)

“…Finally, we predicted the development trajectory of the coupled system in the next 20 years. …”

Impact of COVID-19 on early intervention referrals (Zellner et al., 2025) by Matthew A. Zellner (12043395)

“…</p><p dir="ltr"><b>Results: </b>Overall, we found large decreases in service provision rates for the first 2 timepoints; however, by September 2021, rates had moved closer to expected prepandemic levels. …”

Table 1_Reconstructing Holocene centennial cooling events: synthesized temperature changes, chronology, and forcing in the Northern Hemisphere.xlsx by Sergey A. Gorbarenko (13696381)

“…Based on the constructed stack, we identified and categorized 15 notable Holocene centennial cooling events (HCCEs) in the NH (period with temperature decreases). …”

Data Sheet 1_Reconstructing Holocene centennial cooling events: synthesized temperature changes, chronology, and forcing in the Northern Hemisphere.docx by Sergey A. Gorbarenko (13696381)

“…Based on the constructed stack, we identified and categorized 15 notable Holocene centennial cooling events (HCCEs) in the NH (period with temperature decreases). …”

Table 4_Scalability of spheroid-derived small extracellular vesicles production in stirred systems.xlsx by Thibaud Dauphin (21196820)

“…</p>Methods<p>We used a human β cell line, grown as monolayer or in suspension as spheroid in stirred systems. …”