Supplementary file 1_Pedunculoside targets P2X7R to protect against myocarditis by regulating the NLRP3/PIP2/MAPK signaling pathway.docx by Youqiong Zhuo (10361585)

“…</p>Results<p>We found that PE demonstrated inhibition of H9c2 cell death and decreased ROS, Ca²⁺ levels, and MMP loss induced by LPS + ATP. …”

Presentation1_Exchange flow in a highly stratified fjord in drought conditions.pdf by Elias Pinilla (20400329)

“…In 2016, reduced freshwater input decreased exchange flow and increased salinity compared to 2018. …”

Video 1_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.mp4 by Sofie Vandendriessche (638514)

“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”

A well-resolved phylogeny of <i>Epilobium</i> (Onagraceae) taxa in the British Isles finds no correlation between genomic divergence and the outcome of hybridisation by Kaitlin Saward (22126620)

“…All were likely to be F₁ hybrids.</p> <p>We did not detect a significant relationship between parental divergence and hybridisation likelihood and/or hybrid fertility in <i>Epilobium</i> sect. …”

Data Sheet 1_A distal regulatory element regulates Wx gene expression and the amylose content in rice.pdf by Qingqing Yang (1628146)

“…The amylose content of Wx^b-cre mutant decreased by 21.43%–31.51% compared with that of wild-type rice with the Wx^b allele. …”

Supplementary Material for: Impact of early oral feeding on postoperative outcomes after elective colorectal surgery: a systematic review and meta-analysis by Lee S.Y. (4128808)

“…Data were pooled, and the overall effect size was calculated. Results: We screened 13 studies, and 1,556 patients were included in the analysis. …”

Data Sheet 1_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.docx by Sofie Vandendriessche (638514)

“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”

Video 2_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.mp4 by Sofie Vandendriessche (638514)

“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”

Image 1_Snowmelt seepage fluxes of dissolved organic matter in forest and grassland – a molecular-level case study from the Hainich Critical Zone Exploratory, Germany.pdf by Chen Huang (202847)

“…Notably, the unique DOM components specific to each ecosystem increased during peak fluxes in the forest but decreased in the grassland. We suggest that an overall higher molecular richness and the broader functional metabolic potentials in grassland may account for its relatively greater DOM stability compared to the forest during peak snowmelt events.…”

Table 1_Morphophysiological and transcriptomic analyses during the development of microspores and megaspores in Orobanche coerulescens.xlsx by Kelin Cui (20936231)

“…We also investigated the key regulatory genes in the metabolic pathways of phytohormones that are closely related to the development of microspores and megaspores using transcriptome sequencing technology.…”

Presentation 1_A framework for modeling county-level COVID-19 transmission.pdf by Yida Bao (15255682)

“…Ordinary Least Squares regression establishes a baseline for analyzing COVID-19 confirm case counts for each county. We then use Moran's I to evaluate spatial clustering, prompting Spatial Autoregressive and Spatial Error Models when autocorrelation is significant. …”

Table 2_Unsupervised machine learning revealed a correlation between low-dose statins and favorable outcomes in ICH patients.docx by Chaohua Cui (1793155)

“…Statins administered at normal doses may contribute to hematoma expansion. We employed unsupervised machine learning methods and found that low-dose statins improve the prognosis of ICH.…”

Table 1_Unsupervised machine learning revealed a correlation between low-dose statins and favorable outcomes in ICH patients.docx by Chaohua Cui (1793155)

“…Statins administered at normal doses may contribute to hematoma expansion. We employed unsupervised machine learning methods and found that low-dose statins improve the prognosis of ICH.…”

Image_1_What can be observed in intervertebral cartilage endplate with aging? An animal model study of excessive axial mechanical loading.PNG by Zhouyang Hu (8410554)

“…MRI analysis revealed significant degenerative changes in the loaded Co8/9 CEP, including decreased signal intensity and the formation of Schmorl’s nodes at 8 and 12 weeks. …”

Table 1_Effects of gut microbiota dysbiosis on the metabolism and pharmacokinetics of losartan in rats: from endogenous to ceftriaxone-induced dysbiosis.docx by Jiaxuan Xia (13808828)

“…More importantly, we observed a reduction in the oral bioavailability of losartan in rats with gut microbiota dysbiosis. …”

Data Sheet 1_Freshwater transport variation through Fram and Davis Strait influenced by atmospheric circulation.pdf by Jinlong Zhang (175134)

“…The research findings reveal that over the past four decades, the FWT through the straits has not exhibited the anticipated continuous growth. Instead, we observed distinct temporal shifts in regional freshwater export patterns: The FWT in Fram Strait experienced significant increase prior to the 21st century (trend of 10.14 mSv/10yr during 1980-2000), whereas the FWT in Davis Strait showed acceleration after 2000 (trend of 13.69 mSv/10yr). …”

Mendelian randomization analysis revealed that albuminuria is the key factor affecting socioeconomic status in CKD patients by Jianbo Qing (12864269)

“…In the multivariable MR analysis, both CKD (OR = 0.867, 95% CI: 0.786–0.957, <i>p</i> = 0.0045) and eGFR (OR = 0.065, 95% CI: 0.010–0.437, <i>p</i> = 0.0049) exhibited significant effects on income. This study underscores that higher albuminuria levels in CKD patients are associated with decreased income and emphasizes the importance of effective management and treatment of albuminuria in CKD patients to mitigate both social and personal economic burdens.…”

Table 1_Association between oxidative balance score and methylation cycle biomarkers in US adults: insights from the national health and nutrition examination survey.docx by Xuna Liu (16988607)

“…RCS regression analysis revealed that with the increase in OBS, serum folate, RBC folate, vitamin B6, and vitamin B12 also increased, while HCY and MMA decreased.</p>Conclusion<p>Our findings demonstrate a significant relationship between OBS and the methylation cycle. …”

DataSheet1_Hepatic and pulmonary macrophage activity in a mucosal challenge model of Ebola virus disease.zip by Timothy G. Wanninger (20296455)

“…Background<p>The inflammatory macrophage response contributes to severe Ebola virus disease, with liver and lung injury in humans.</p>Objective<p>We sought to further define the activation status of hepatic and pulmonary macrophage populations in Ebola virus disease.…”

DataSheet2_Hepatic and pulmonary macrophage activity in a mucosal challenge model of Ebola virus disease.zip by Timothy G. Wanninger (20296455)

“…Background<p>The inflammatory macrophage response contributes to severe Ebola virus disease, with liver and lung injury in humans.</p>Objective<p>We sought to further define the activation status of hepatic and pulmonary macrophage populations in Ebola virus disease.…”