A total of 700 DEGs. by Wei He (131453)

“…Compared with normal tissues, AAD tissues exhibited a significant decrease in CD8 T cells and an increase in NK cells and macrophages.…”

Raw data of Figs 1–6 in this study. by Qi Qi Lu (17721401)

“…When gut epithelial PGAM5 receptor and apoptosis were inhibited by PGAM5-specific siRNA, inhibitor (LFHP-1c) and apoptosis inhibitor (Z-VAD-FMK), trans-epithelial electrical resistance (TEER) and TJs expression were obviously increased, and intestinal permeability was evidently decreased. …”

The complete dataset used for our analysis. by Sarah J. Noe (19846136)

“…<div><p>The economic, socio-political, and cultural significance of camelids in the Andean region is well-recognized, yet an understanding of their management evolution over pre-historical periods remains limited. …”

R markdown of our complete analysis. by Sarah J. Noe (19846136)

“…<div><p>The economic, socio-political, and cultural significance of camelids in the Andean region is well-recognized, yet an understanding of their management evolution over pre-historical periods remains limited. …”

Study methods flow chart. by Luis Polo-Ferrero (20513578)

“…The expected results are that PT will significantly improve functionality and body composition compared to other forms of exercise (MT) and no physical activity. …”

Table 2_Integration analysis of microRNAs as potential biomarkers in early-stage lung adenocarcinoma: the diagnostic and therapeutic significance of miR-183-3p.docx by Guodong Huang (1595956)

“…The miRNAs expression results were verified using qRT-PCR. Additionally, we evaluated the clinical significance of miRNAs by the TCGA database. miR-183-3p was chosen for subsequent biological functional studies by cell proliferation assays, cell migration and cell invasion assays, cell apoptosis and cell cycle assays in LUAD cells. …”

Table 1_Integration analysis of microRNAs as potential biomarkers in early-stage lung adenocarcinoma: the diagnostic and therapeutic significance of miR-183-3p.docx by Guodong Huang (1595956)

“…The miRNAs expression results were verified using qRT-PCR. Additionally, we evaluated the clinical significance of miRNAs by the TCGA database. miR-183-3p was chosen for subsequent biological functional studies by cell proliferation assays, cell migration and cell invasion assays, cell apoptosis and cell cycle assays in LUAD cells. …”

Table 3_Integration analysis of microRNAs as potential biomarkers in early-stage lung adenocarcinoma: the diagnostic and therapeutic significance of miR-183-3p.docx by Guodong Huang (1595956)

“…The miRNAs expression results were verified using qRT-PCR. Additionally, we evaluated the clinical significance of miRNAs by the TCGA database. miR-183-3p was chosen for subsequent biological functional studies by cell proliferation assays, cell migration and cell invasion assays, cell apoptosis and cell cycle assays in LUAD cells. …”

Characteristics of studied included. by Razieh Bidhendi-Yarandi (7139387)

“…The results of meta-regression analyses revealed a statistically significant trend showing a gradual decrease in the prevalence of the composite outcome of anxiety and/or depression over time (RD = -0.004,P = 0.022). …”

Flowchart of the search process. by Razieh Bidhendi-Yarandi (7139387)

“…The results of meta-regression analyses revealed a statistically significant trend showing a gradual decrease in the prevalence of the composite outcome of anxiety and/or depression over time (RD = -0.004,P = 0.022). …”

Table 1_Prognostic significance of early alpha fetoprotein and des-gamma carboxy prothrombin responses in unresectable hepatocellular carcinoma patients undergoing triple combinati... by Teng Zhang (457128)

“…Background<p>Recent advancements in combination therapy for unresectable hepatocellular carcinoma (uHCC) have shown promise, but reliable serological prognostic indicators are currently lacking for patients undergoing triple combination therapy of stereotactic body radiation therapy (SBRT), immunotherapy, and targeted therapy. We aimed to investigate the prognostic significance of early alpha fetoprotein (AFP) and des-gamma-carboxy prothrombin (DCP) responses in these patients.…”

S1 File - by Vasanthi Avadhanula (259546)

“…Cases included SARS-CoV-2 infected individuals with extremely high viral loads early in their illness, individuals having low SARS-CoV-2 viral loads early in their infection, and individuals testing negative for SARS-CoV-2. We could identify widespread transcriptional host responses to SARS-CoV-2 infection that were initially most strongly manifested in patients with extremely high initial viral loads, then attenuating within the patient over time as viral loads decreased. …”

Flow Chart of Study Participant Selection. by Zhi Jin (3742471)

“…Notably, individuals with long sleep duration (>9 hours) had a significantly decreased risk of CVD (OR: 0.36, 95% CI: 0.15–0.85, P = 0.02) compared to those with shorter sleep durations.…”

Cascade of care by HCV testing model. by Bao Vu Ngoc (14551955)

“…We engaged eight community-based organizations (CBOs) and 10 public and private clinics in offering HCVST using oral fluid-based HCV rapid antibody tests along with standard or provider-led HCV testing (HCVT). …”

Factors associated with first-time HCV testing. by Bao Vu Ngoc (14551955)

“…We engaged eight community-based organizations (CBOs) and 10 public and private clinics in offering HCVST using oral fluid-based HCV rapid antibody tests along with standard or provider-led HCV testing (HCVT). …”

Structure-Affinity-Pharmacokinetics Relationships of Novel ¹⁸F‑Labeled 1,4-Diazepane Derivatives for Orexin 1 Receptor Imaging by Yui Ishizaka (19922137)

“…In a biodistribution study using normal mice, [¹⁸F]­BTF exhibited brain uptake, and radioactivity in the brain was significantly decreased by preinjection of unlabeled BTF. …”

Clinical characteristics. by Clemens Plattner (21567706)

“…<div><p>Aims</p><p>Family history for diabetes (FHD) is a strong risk factor for type 2 diabetes (T2D), however, little is known on its effects on the outcome. Here we aimed to analyse the effects of FHD on diabetes-related outcome.…”

Metabolome data of the discovery cohort. by Feng Gao (3548)

“…The results showed that compared with HC, five metabolites, including DL-stachydrine, D-(+)-pipecolinic acid, furazolidone, L-arginine and 5α-dihydrotestosterone glucuronide were significantly elevated and one metabolite, prenylcysteine, was significantly decreased in the serum of OC, and that the increase in L-arginine and the decrease in prenylcysteine led to impaired urea cycling and a high risk of developing atherosclerosis, respectively. …”

Results of redundancy analysis. by Bianhua Zhang (22430652)

“…<div><p>In order to clarify the effects of long-term coal gangue(CG) dump on the surrounding soil bacterial community structure, we selected the CG dump formed during the mining of Tunlan coal mine in Gujiao city, Shanxi province in China as the study area to conduct a comprehensive study, the experimental design included six distinct zones: control soil area with no impaction (NC), undisturbed control sediment area (NL), atmospheric dry and wet deposition area (MC), upstream (MLS), midstream (MLZ) and downstream (MLX) in the leachate flow area (LFA), Using high-throughput sequencing technology and related software analysis, we obtained the following key findings: The heavy metal contents of Cr and Cd were different significantly in MC and NC (p < 0.05),Cr (90.18 mg·kg-1) in MC was higher than that in NC (65.29 mg·kg-1) (p < 0.05), while Cd (0.09 mg·kg-1) was lower than that in NC (0.14 mg·kg-1) (p < 0.05), and there was no significant differences in Cu, Zn, As and Pb between MC and NC (p > 0.05). …”

Analysis of the correlation between pharyngeal microbiomics, metabolomics and clinical indicators between OC and HC. by Feng Gao (3548)