ELOVL6 as a Therapeutic Target: Disrupting c-MYC-Driven Lipid Metabolism to Enhance Chemotherapy in Pancreatic Cancer حسب Ana García-García (17779885)

"…Initially, we show the direct regulation of ELOVLs expression by c-MYC in various PDAC mouse models and cell lines, elucidating its upregulation during transformation and tumor progression. …"

Image 2_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif حسب Kai Liu (159026)

"…Common comorbidities in the diabetic group were hypertension, cerebrovascular disease, chronic kidney disease and cardiovascular disease. We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …"

Image2_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

Image 2_Slavs in the closet: computational genomic analysis reveals cryptic slavic signatures in the Avar Khaganate and their contribution to medieval Croatian population formation... حسب Todor Chobanov (22288636)

"…Statistical modeling demonstrates that contemporary Croatian populations formed through three distinct migration waves, with 50%–60% total Slavic ancestry and 20%–25% pre-Slavic Balkan continuity. Significantly, we identified individuals with Slavic genetic profiles in prestigious Avar burial contexts, questioning established understanding of social hierarchies within the Khaganate. …"

Image 3_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif حسب Kai Liu (159026)

"…Common comorbidities in the diabetic group were hypertension, cerebrovascular disease, chronic kidney disease and cardiovascular disease. We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …"

Unraveling the immunosuppressive role of Elastase B produced by cystic fibrosis isolates of <i>Pseudomonas aeruginosa</i> in an organotypic 3D lung epithelial cell model حسب Merel Wauters (21333023)

"…Compared to the <i>lasB</i> mutant, the wild-type strain significantly decreased inflammation by degrading MCP-1, IL-1β, GM-CSF, and IL-8. …"

Image1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png حسب Huijun Zhou (60485)

"…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …"

Image 1_The clinical features and outcomes of diabetes patients infected with COVID-19: a systematic review and meta-analysis comprising 192,693 patients.tif حسب Kai Liu (159026)

"…Common comorbidities in the diabetic group were hypertension, cerebrovascular disease, chronic kidney disease and cardiovascular disease. We discovered that white blood cell count, neutrophil count, inflammatory marker levels, D-dimer, urea, precursor of the brain natriuretic peptide (Pro-BNP) increased and lymphocyte count, estimated glomerular filtration rate (eGFR), albumin decreased significantly in the diabetic group in laboratory test results. …"

Data_Sheet_1_Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric hospital admissions in North Italian hospitals, 2017 to 2022: a quasi-experimental study int... حسب Giuseppe Maglietta (12992976)

"…Level change for Mental Disorders significantly decreased during school closure (HRR 0.50, 95%CI 0.30–0.82) but increased during mitigation measures by 28% (HRR 1.28, 95%CI 0.98–1.69).…"

Data_Sheet_1_Effects of COVID-19-targeted non-pharmaceutical interventions on pediatric hospital admissions in North Italian hospitals, 2017 to 2022: a quasi-experimental study int... حسب Giuseppe Maglietta (12992976)

"…Level change for Mental Disorders significantly decreased during school closure (HRR 0.50, 95%CI 0.30–0.82) but increased during mitigation measures by 28% (HRR 1.28, 95%CI 0.98–1.69).…"

Data Sheet 5_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

"…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"

Supplementary file 1_The bridge between anxiety and insomnia symptoms among Chinese adults before and after SARS-CoV-2 vaccination: a network analysis.doc حسب Yan Liu (25061)

"…</p>Conclusions<p>The proportion of participants experiencing anxiety and insomnia decreased significantly after SARS-CoV-2 vaccination. …"

Data Sheet 9_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

"…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"

Data Sheet 6_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

"…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"

Raw images. حسب Dahae Lee (3125157)

"…PPD, Rg1, Rb2, and Rg3 inhibited lipid accumulation in PA-treated HepG2 cells. PA significantly decreased lipid levels in HepG2 cells, which was prevented by PPD, Rg1, Rb2, and Rg3. …"

Data Sheet 10_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

"…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"

Data Sheet 8_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

"…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"

Data Sheet 1_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

"…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"

Data Sheet 11_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.pdf حسب Erdengqieqieke Ye (19542808)

"…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"

Supplementary file 1_Global, regional, and national burdens of congenital heart anomalies from 1990 to 2021, and projections to 2050.xlsx حسب Erdengqieqieke Ye (19542808)

"…Background<p>Congenital heart anomalies (CHAs) are the most prevalent birth defects, significantly impacting pediatric populations and healthcare systems worldwide. …"