Image 2_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.tif حسب Chanchan Xiao (9522614)

"…</p>Results<p>Our findings revealed that mutant epitopes in the Omicron variant led to escape from antigen presentation and diminished CD8 T-cell immune responses. We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …"

Supplementary Material for: Leveraging NLP for Psychiatric Phenotyping from Spanish EHR: Enabling the Investigation of Transdiagnostic Symptom Profiles at Scale حسب figshare admin karger (2628495)

"…The COMBINED algorithm improved overall recall, without significantly decreasing precision (F1 of 0.78 and 0.77 on HOMO and CSJDM, respectively). …"

Image 1_Characterizing HLA-A2-restricted CD8+ T-cell epitopes and immune responses to Omicron variants in SARS-CoV-2-inactivated vaccine recipients.tif حسب Chanchan Xiao (9522614)

"…</p>Results<p>Our findings revealed that mutant epitopes in the Omicron variant led to escape from antigen presentation and diminished CD8 T-cell immune responses. We identified two epitopes associated with decreased CD8 T-cell reactivity post-Omicron variant emergence. …"

Table 1_Eculizumab for the acute attack of neuromyelitis optica spectrum disorder.docx حسب Qingqing Zhuang (22109089)

"…Visual field mean deviation improved from −22.4 dB to −2.0 dB (p = 0.008). …"

Table 1_Obinutuzumab in systemic lupus erythematosus: a real-world experience.docx حسب Chunmei Wu (3202050)

"…By week 48, 37.5% achieved DORIS remission, 32.1% LLDAS, and 19.6% remained clinically stable. Mean SLEDAI-2K decreased from 11.75 ± 9.31 (range: 0 to 46) to 1.45± 1.93 (range: 0 to 8). …"

Data Sheet 2_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.docx حسب Wenjun Li (41954)

"…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …"

Data Sheet 1_Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy.pdf حسب Wenjun Li (41954)

"…The levels of pro-inflammatory cytokines in blood were also significantly decreased in shPD-L1 treated mice. Additionally, T cell apoptosis rates in the spleen showed a 2-fold increase in treated mice. …"

30-year trends in incidence of acute STEMI and NSTEMI in the Belgian Province of Luxembourg. A long-term follow-up of the MONICA-BELLUX registry حسب Bernhard L. Gerber (10171583)

"…</p><p>b) What this study adds</p><p>In a 30-year registry in Luxembourg using modern AMI definitions, overall, AMI incidence decreased significantly, primarily due to a 3.8-fold reduction in STEMI.…"

Supplementary Material for: Anti-Vascular Endothelial Growth Factor Treatment Outcomes in Macular Telangiectasia: A Systematic Review حسب figshare admin karger (2628495)

"…In non-proliferative MacTel, mean CMT changed from 201 (32) µm to 199 (29) µm. …"

Glia-targeted 5-HT_2A receptor expression in adults reopens experience-dependent synaptic glomeruli pruning. حسب Vanessa Kay Miller (19775496)

"…All the individual data points are shown with the mean ± SEM. Significance is indicated as <i>p</i> < 0.0001 (****) and <i>p</i> > 0.05 (not significant, ns). …"

Data Sheet 1_Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles.... حسب Ettore Silvagni (9576002)

"…When assessing the interaction between the period of drug delivery and the treatment with JAKis on the risk of new CVEs, no significant interaction was observed (p = 0.838), while the interaction was statistically significant for baseline CV risk (p = 0.007).…"

Data Sheet 2_Frailty and cardiovascular safety of JAK inhibitors versus TNF inhibitors in rheumatoid arthritis: a real-world comparative study of drug effects and patient profiles.... حسب Ettore Silvagni (9576002)

"…When assessing the interaction between the period of drug delivery and the treatment with JAKis on the risk of new CVEs, no significant interaction was observed (p = 0.838), while the interaction was statistically significant for baseline CV risk (p = 0.007).…"

Table 1_A murine model of gestational diabetes reveals MASLD risk and alterations in markers of hepatic mitochondrial metabolism.docx حسب Grace E. Shryack (21596426)

"…</p>Results<p>Progressing gestation in both CD and GDM dams significantly decreased protein and mRNA markers of hepatic mitochondrial biogenesis (Pgc1-α, Tfam), autophagy (Atg5, Sqstm1), mitophagy (Pink1, Bnip3) and lipid handling (Ampk, pAMPK/AMPK, FAS, ACC, pACC, Mttp) with a main effect for time (P<0.05). …"

Additional file 2 of Single-cell profiling reveals periosteal signatures of impaired periosteal cells proliferation in a drill-hole model of type 2 diabetes حسب Xing Ji (3096735)

"…Data are shown as mean ± SD. **P < 0.01.…"

Data Sheet 1_Dietary resveratrol and β-Hydroxy-β-Methylbutyric acid enhance flavor and modulate intramuscular fat in Tibetan sheep: insights from transcriptomics and lipidomics.zip... حسب Xuan Chen (158617)

"…Among medium- and long-chain fatty acids, the H-RES-HMB group showed significantly decreased SFAs (C17:0 and C18:0) (p < 0.05) and significantly increased MUFAs (C15:1N5 and C18:1N9) and PUFAs (C18:2N6, C18:3N6, C18:3N3, C20:3N6, and C20:3N3) (p < 0.05). …"

Table 6_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx حسب Zemin Liu (224306)

"…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …"

Table 3_Apoptosis and autophagy promote Babesia microti infection in tick midguts: insights from transcriptomic and functional RNAi studies.docx حسب Songqin Chen (9625886)

"…Functional assays demonstrated that RNA interference (RNAi)-mediated knockdown of caspase-7, caspase-9, and ATG5 significantly reduced the burden of B. microti. Conversely, pharmacological induction of autophagy using rapamycin increased B. microti load, whereas inhibition with 3-methyladenine (3-MA) decreased B. microti load.…"

Table_3_Functional Characterization of Olfactory Proteins Involved in Chemoreception of Galeruca daurica.DOCX حسب Ling Li (38566)

"…The EAG response of G. daurica females to 2-hexenal was significantly decreased in dsRNA-OBP15-injected treatment compared to the control, and the dsRNA-CSP5-treated females significantly reduced EAG response to eight tested host volatiles (1,3-dithiane, 2-hexenal, methyl benzoate, dimethyl trisulfide, myrcene, hexanal, 1,3,5-cycloheptatriene, and p-xylene). …"

Data Sheet 1_Saikosaponin A induces cellular senescence in triple-negative breast cancer by inhibiting the PI3K/Akt signalling pathway.docx حسب Yingchao Wu (2870927)

"…Existing therapeutic agents are generally accompanied by significant side effects. Here, we highlight Saikosaponin A (SSA), a promising natural metabolite characterized by low toxicity, demonstrating significant efficacy against breast cancer through the induction of cellular senescence.…"

Table 7_Trends in immune cell profiles of osteomyelitis: a clinical study supported by Mendelian randomization analysis.docx حسب Zemin Liu (224306)

"…Subgroup analysis revealed significantly increased lymphocyte counts and decreased neutrophil counts across all subgroups, except for the mixed infection group. …"