Supplementary Material for: Effect of frail phenotype on cardiorenal risk and healthcare utilization in older patients with chronic kidney disease by Sun C.-Y. (10070377)

“…The primary composite renal outcome was a ≥ 25 % decrease in eGFR concurrent with CKD stage progression or dialysis initiation. …”

Data Sheet 1_Groundwater stress in Europe—assessing uncertainties in future groundwater discharge alterations due to water abstractions and climate change.docx by Linda Söller (19967598)

“…Groundwater stress is defined as any alteration in GWD since ecosystems are adapted to an equilibrium state. Focusing on decreasing GWD, which is generally more harmful than increasing GWD, we quantified the future GWSI in Europe by integrating scenarios of GWR and GWA in 2070–2099. …”

Data Sheet 1_Choroidal thickness as a biomarker of systemic inflammation in patients with polymyalgia rheumatica.docx by Laura Trives-Folguera (22449472)

“…We found a significant decrease in all laboratory and clinical parameters. …”

Table 1_Sex-specific association between body mass index and cerebral microbleed progression in adults aged 50–85 years.docx by Cindy W. Yoon (10146428)

“…In women, each 1 kg/m² increase in BMI was significantly associated with a decrease in the 2-year change in the number of total CMBs after adjustment for age and baseline CMB count [β = −0.120, 95% confidence interval (CI): −0.202 to −0.037, p = 0.005]. …”

Effects of message content condition on outcomes. by Rhyan N. Vereen (10765678)

“…Outcomes were intentions to decrease sugary drink consumption (primary outcome; range 1–7), knowledge of (range 0–4) and perceived susceptibility to health harms (range 1–5) and sharing intentions (range 0–3).…”

Participant characteristics, N = 502. by Rhyan N. Vereen (10765678)

“…Outcomes were intentions to decrease sugary drink consumption (primary outcome; range 1–7), knowledge of (range 0–4) and perceived susceptibility to health harms (range 1–5) and sharing intentions (range 0–3).…”

Data Sheet 1_Global burden of lung cancer in adolescents and adults aged 15–45: analysis of the global burden of disease study (1990–2021).pdf by Ziqi Han (12840074)

“…</p>Results<p>Our findings reveal that while the number of lung cancer cases aged 15–45 increased by 22.1%, the age-standardized prevalence decreased by 23.9%; age-standardized mortality and DALYs declined significantly over the past three decades. …”

Sample of study stimuli by content condition. by Rhyan N. Vereen (10765678)

“…Outcomes were intentions to decrease sugary drink consumption (primary outcome; range 1–7), knowledge of (range 0–4) and perceived susceptibility to health harms (range 1–5) and sharing intentions (range 0–3).…”

Table 1_Association between sedentary behavior, physical activity, and osteoarthritis: results from NHANES 2007–2020 and Mendelian randomization analysis.xls by Jiangqin He (18852987)

“…A U-shaped relationship was observed between PA and OA risk, with a decrease in OA incidence as PA levels increased, although the protective effect of PA was less pronounced in individuals with severe SB. …”

Table 2_Association between sedentary behavior, physical activity, and osteoarthritis: results from NHANES 2007–2020 and Mendelian randomization analysis.xls by Jiangqin He (18852987)

“…A U-shaped relationship was observed between PA and OA risk, with a decrease in OA incidence as PA levels increased, although the protective effect of PA was less pronounced in individuals with severe SB. …”

Ketamine wash-in. by Anne S. Fleiner (20496284)

“…(ii) The change in post-burst spiking after the wash-in of 20 μM and 100 μM was not significant compared to the control (MWU test). However, the decrease in post-burst spiking was significantly larger after the wash-in of 100 μM ketamine than with 20 μM (MWU test). …”

Supplementary file 1_Short-term fasting before living kidney donation has an immune-modulatory effect.pdf by Christiaan A. J. Oudmaijer (12006320)

“…STF changes the levels and phenotype of immune cells, reducing the abundance and activation of T cells, including regulatory T cells, increased presence of (naïve) B cells, and elevation of type 1 conventional DCs (cDC1s). In addition, a decrease in central memory T cells was observed.</p>Discussion<p>In this study, we observed significant changes due to fasting in B cells, T cells, and DCs, specifically toward less specialized lymphocytes, suggesting an arrest in B and T cell development. …”

Data Sheet 1_Short-term fasting before living kidney donation has an immune-modulatory effect.docx by Christiaan A. J. Oudmaijer (12006320)

“…STF changes the levels and phenotype of immune cells, reducing the abundance and activation of T cells, including regulatory T cells, increased presence of (naïve) B cells, and elevation of type 1 conventional DCs (cDC1s). In addition, a decrease in central memory T cells was observed.</p>Discussion<p>In this study, we observed significant changes due to fasting in B cells, T cells, and DCs, specifically toward less specialized lymphocytes, suggesting an arrest in B and T cell development. …”

Supplementary Material for: The impact of age and body composition on the agreement between estimated and measured GFR in heart transplant recipients by Hornum M. (16418109)

“…During the first year after HTx, mean weight increased by 4.2 kg (CI:3.2–5.1) followed by an annual decrease of 0.35 kg/year (Cl:-0.05–0.74). mGFR increased by 7.5 ml/min (Cl:3.2–11.8) the first year but was stable hereafter (0.0 ml/min/year CI:-1.0–1.0). …”

Table 1_Clinical performance of Hedia Diabetes Assistant bolus calculator for diabetes management: a real-world retrospective cohort study.docx by Kenney Fehrenkamp Pedersen (20944706)

“…After 12 weeks, LBGI significantly improved from 0.73 to 0.61 (17% decrease, P < 0.001) with no significant changes in HBGI, and eA1c. …”

Image 2_Changes in serum concentration of perioperative inflammatory cytokines following the timing of surgery among mild–moderate traumatic brain injury patients and factors assoc... by Hervé Monka Lekuya (17285065)

“…Serum levels of TNF-α were significantly higher after surgeries done >48 h compared to those done ≤48 h (p = 0.0327); whereas, the difference in post-operative mean serum levels of IL-10 was significantly increased in patients who developed later SSI compared to those who did not (11.56 versus −0.58 pg.…”

Image 3_Changes in serum concentration of perioperative inflammatory cytokines following the timing of surgery among mild–moderate traumatic brain injury patients and factors assoc... by Hervé Monka Lekuya (17285065)

“…Serum levels of TNF-α were significantly higher after surgeries done >48 h compared to those done ≤48 h (p = 0.0327); whereas, the difference in post-operative mean serum levels of IL-10 was significantly increased in patients who developed later SSI compared to those who did not (11.56 versus −0.58 pg.…”

Image 1_Changes in serum concentration of perioperative inflammatory cytokines following the timing of surgery among mild–moderate traumatic brain injury patients and factors assoc... by Hervé Monka Lekuya (17285065)

“…Serum levels of TNF-α were significantly higher after surgeries done >48 h compared to those done ≤48 h (p = 0.0327); whereas, the difference in post-operative mean serum levels of IL-10 was significantly increased in patients who developed later SSI compared to those who did not (11.56 versus −0.58 pg.…”

Table 1_Ten days of supplementation with a standardized Boswellia serrata extract attenuates soreness and accelerates recovery after repeated bouts of downhill running in recreatio... by Dawna Salter (18498396)

“…Blood and urine samples collected at baseline, before, and after DHR were analyzed for inflammation-related biomarkers. VAS scores significantly increased while muscle strength decreased from baseline measures after DHR regardless of group assignment (main effect of time p < 0.001). …”

Impact of Oral Semaglutide on Kidney Outcomes in People with Type 2 Diabetes: Results from the SOUL Randomized Trial by Johannes F. E. Mann (22017555)

“…The 4-point outcome occurred in 112 (2.3%) and 129 (2.7%), respectively (HR 0.86 [0.66- 1.10]; P=0.22). Mean annual eGFR decline was less with oral semaglutide than placebo (−1.67 vs −2.06 mL/min/1.73 m2; estimated treatment difference 0.40 [0.27-0.53]; P < 0.0001). …”