Data Sheet 1_Cynaroside ameliorates TNBS-induced colitis by inhibiting intestinal epithelial cell apoptosis via the PI3K/AKT signalling pathway.pdf by figshare admin frontiersin (4545187)

“…Combining network pharmacology prediction analysis with our validation data from animal models and colonic organoids, we demonstrated that Cyn significantly inhibits IEC apoptosis, as indicated by a decrease in the proportion of TUNEL-positive cells and changes in apoptosis-related protein levels. …”

Image 1_Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes.tif by Yunus E. Dogan (19859574)

“…</p>Conclusion<p>Taken together, this study demonstrates a new protective effect of hAAT in normalizing blood pressure after the development of saltinduced hypertension in juvenile mice in a mechanism involving a decrease in NKCC2 membrane expression, presumably due to decreased levels of DAGs in the plasma membrane and a subsequent decrease in PKC activity.…”

Table 1_Alpha 1-antitrypsin mitigates salt-sensitive hypertension in juvenile mice by reducing diacylglycerol concentrations and protein kinase C activity in kidney membranes.docx by Yunus E. Dogan (19859574)

“…</p>Conclusion<p>Taken together, this study demonstrates a new protective effect of hAAT in normalizing blood pressure after the development of saltinduced hypertension in juvenile mice in a mechanism involving a decrease in NKCC2 membrane expression, presumably due to decreased levels of DAGs in the plasma membrane and a subsequent decrease in PKC activity.…”

Population connectivity disruption experiment Daphnia data by Yiwen Xu (12943412)

“…At the patch scale, the magnitude of this decrease was significantly affected by the position of the patch within the network. …”

Video 1_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov by Katrina Knight (17391604)

“…However, concerns regarding the deformability of the prototype MUS, mechanical cut Gynecare TVT prompted manufacturers to use techniques like laser cutting, heat-sealing, and the inclusion of an interwoven stabilizing suture to decrease deformation with loading. We hypothesized that a laser cut or heat-sealed MUS would be stiffer but deform less, and experience less permanent elongation as compared to a mechanical cut MUS. …”

Video 2_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov by Katrina Knight (17391604)

“…However, concerns regarding the deformability of the prototype MUS, mechanical cut Gynecare TVT prompted manufacturers to use techniques like laser cutting, heat-sealing, and the inclusion of an interwoven stabilizing suture to decrease deformation with loading. We hypothesized that a laser cut or heat-sealed MUS would be stiffer but deform less, and experience less permanent elongation as compared to a mechanical cut MUS. …”

Video 3_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov by Katrina Knight (17391604)

“…However, concerns regarding the deformability of the prototype MUS, mechanical cut Gynecare TVT prompted manufacturers to use techniques like laser cutting, heat-sealing, and the inclusion of an interwoven stabilizing suture to decrease deformation with loading. We hypothesized that a laser cut or heat-sealed MUS would be stiffer but deform less, and experience less permanent elongation as compared to a mechanical cut MUS. …”

Video 5_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov by Katrina Knight (17391604)

“…However, concerns regarding the deformability of the prototype MUS, mechanical cut Gynecare TVT prompted manufacturers to use techniques like laser cutting, heat-sealing, and the inclusion of an interwoven stabilizing suture to decrease deformation with loading. We hypothesized that a laser cut or heat-sealed MUS would be stiffer but deform less, and experience less permanent elongation as compared to a mechanical cut MUS. …”

Video 4_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.mov by Katrina Knight (17391604)

“…However, concerns regarding the deformability of the prototype MUS, mechanical cut Gynecare TVT prompted manufacturers to use techniques like laser cutting, heat-sealing, and the inclusion of an interwoven stabilizing suture to decrease deformation with loading. We hypothesized that a laser cut or heat-sealed MUS would be stiffer but deform less, and experience less permanent elongation as compared to a mechanical cut MUS. …”

Data Sheet 1_Characterizing the structural properties and porosity of mid-urethral slings with varied manufacturing techniques.docx by Katrina Knight (17391604)

“…However, concerns regarding the deformability of the prototype MUS, mechanical cut Gynecare TVT prompted manufacturers to use techniques like laser cutting, heat-sealing, and the inclusion of an interwoven stabilizing suture to decrease deformation with loading. We hypothesized that a laser cut or heat-sealed MUS would be stiffer but deform less, and experience less permanent elongation as compared to a mechanical cut MUS. …”

Supplementary file 1_Antibiotic pretreatment inhibits white band disease infection by suppressing the bacterial pathobiome.docx by Jason D. Selwyn (2633932)

“…We found the prophylactic use of antibiotics led to significantly reduced infection rates in disease exposed corals with a 30-percentage point decrease in the infection rate. …”

Supplementary file 2_Antibiotic pretreatment inhibits white band disease infection by suppressing the bacterial pathobiome.csv by Jason D. Selwyn (2633932)

“…We found the prophylactic use of antibiotics led to significantly reduced infection rates in disease exposed corals with a 30-percentage point decrease in the infection rate. …”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”

First Sila-Vitamin D Analogues: Design, Synthesis, Structural Analysis and Biological Activity by Julian Loureiro (20357035)

“…These sila-analogues show similar VDR binding and transcriptional activity in comparison with the natural hormone 1,25D₃, but with significantly less hypercalcemic activity. The new analogues, when combined with chemotherapy, significantly decrease cell proliferation.…”