Data Sheet 1_Factors affecting posaconazole plasma concentrations: a meta-analysis and systematic review.docx by Ruochen Qu (16946790)

“…High-fat meals, age, and sex did not have a significant impact on posaconazole oral suspension (POS) concentrations. …”

Table 1_Platelet-rich plasma improves pain and function in knee osteoarthritis: a retrospective study.docx by Yi-Ting Sun (4691629)

“…</p>Results<p>At 6 months, the median (IQR) VAS score significantly decreased from 66.5 (27) to 24 (34) (95% CI = −38 to −30.5), p < 0.001), and WOMAC scores improved from 29 (22) to 12 (14) (95% CI = −16.5 to −12), p < 0.001). …”

Table 1_A dosimetric comparison of non-coplanar volumetric modulated arc therapy and non-coplanar fixed field intensity modulated radiation therapy in hippocampus-avoidance whole-b... by Huaqu Zeng (20601563)

“…VMAT significantly improved the V₃₀ of PTV-brain-SIB (p<0.001), decreased HI (p=0.003), and increased CI (p<0.001). …”

Data Sheet 1_Comparison of the gut microbiota in older people with and without sarcopenia: a systematic review and meta-analysis.zip by Yanqing Ren (2080156)

“…Weighted standardized mean differences (SMDs) and 95% confidence intervals (CIs) for α-diversity index were estimated using a random effects model. …”

<b>Fire Severity Alters Soil Microbial Diversity and Community Stability in a Subtropical Forest Ecosystem</b> by Xuezhao (21803957)

“…Moreover, low-severity fires increased the functional taxa associated with chemoheterotrophic and aerobic chemoheterotrophic bacteria, whereas the ectomycorrhizal fungi was significantly reduced in fired plots. Network analysis indicated that the complexity and connectivity of microbial networks gradually decreased with increasing fire severity.…”

Table 1_Association between serum albumin and severe impairment of activities of daily living in patients with stroke: a cross-sectional study.docx by Ranran Bi (20505614)

“…After adjusting for confounding factors, the multivariate analysis revealed a 7% decrease in severe impairment of ADL after stroke for every unit (g/L) increase in serum albumin levels. …”

Initial evaluation of an intervention to address provider implicit bias in pediatric sickle cell disease pain care: A mixed methods pilot study by Siddika S. Mulchan (21299553)

“…</p> <p>: The aim of this study was to evaluate the feasibility, acceptability, and preliminary impact of an individuation and perspective-taking (IPT) intervention to decrease implicit bias and improve pain treatment clinical decision making in pediatric SCD HCPs.…”

Data Sheet 1_Nonlinear responses of ecosystem carbon fluxes to precipitation change in a semiarid grassland.doc by Hua Chai (280388)

“…<p>Carbon (C) fluxes in semiarid grasslands subject to precipitation variability play a critical role in the terrestrial C cycle. However, how ecosystem C fluxes respond to variability in precipitation (both decreases and increases precipitation along a gradient) remains unclear. …”

Table 1_The impact of public participatory environmental regulation on carbon emission intensity: a policy text analysis.docx by Jianzu Wu (13935369)

“…The findings reveal that: (1) public participatory environmental regulation significantly reduces carbon emission intensity; specifically, baseline regression results indicate that a one-unit increase in public participatory environmental regulation intensity leads to a 0.05 unit decrease in carbon emission intensity, significant at the 1% level; (2) mediation analysis demonstrates that public environmental participation serves as a significant intermediary between environmental regulation and carbon emission reduction; (3) heterogeneity analysis indicates that official characteristics significantly moderate policy effectiveness, with regulations implemented by non-local, shorter-tenured, and less-educated officials showing stronger inhibitory effects on carbon emissions compared to their counterparts. …”

DataSheet2_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.docx by Jung Hoon Cha (19723588)

“…</p>Conclusions<p>Our study underscores the pivotal role of CHIT1 in MASH. The observed significant improvement in inflammation and hepatic fibrosis, particularly at higher doses of the CHIT1 inhibitor, strongly suggests the potential of CHIT1 as a therapeutic target in MASH accompanied by progressive liver fibrosis.…”

DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip by Jung Hoon Cha (19723588)

“…</p>Conclusions<p>Our study underscores the pivotal role of CHIT1 in MASH. The observed significant improvement in inflammation and hepatic fibrosis, particularly at higher doses of the CHIT1 inhibitor, strongly suggests the potential of CHIT1 as a therapeutic target in MASH accompanied by progressive liver fibrosis.…”

The Patient Global Impression of Change as a complementary tool to account for neurobehavioral and mental health symptom improvement for patients with concussion by Rosemay A. Remigio-Baker (7864583)

“…</p> <p>Higher PGIC scores were related to a higher prevalence of clinically-relevant <i>decrease</i> in NSI, PCL-5 or PHQ-8 scores. …”

Supplementary Material for: High-sensitivity Troponin I Measurement in a Large Contemporary Cohort: Implications for Clinical Care by Esau D. (20563829)

“…Male sex, higher HDL-C, higher Hgb A1c, decreasing eGFR, and increasing systolic blood pressure were significant predictors of increased hsTnI. …”

Crossing Barriers<i>: In Vitro</i> Cancer Model for Studying Monocyte Migration across Endothelial Barriers by Mandeep K. Marway (21734690)

“…The endothelial vessel wall plays a significant role in the migration, activation, and polarization of these monocytes. …”

Crossing Barriers<i>: In Vitro</i> Cancer Model for Studying Monocyte Migration across Endothelial Barriers by Mandeep K. Marway (21734690)

“…The endothelial vessel wall plays a significant role in the migration, activation, and polarization of these monocytes. …”

Crossing Barriers<i>: In Vitro</i> Cancer Model for Studying Monocyte Migration across Endothelial Barriers by Mandeep K. Marway (21734690)

“…The endothelial vessel wall plays a significant role in the migration, activation, and polarization of these monocytes. …”

LLL12B, APTO-253, and VK-1727 inhibit cell growth and induce apoptosis in LCL. by Huanzhou Xu (8129922)

Table 1_Efficacy and safety of dietary polyphenol supplements for COPD: a systematic review and meta-analysis.docx by Dongsheng Wu (2469307)

“…</p>Results<p>The randomized controlled trials (RCTs) included in this review examined dietary supplementation with eight polyphenols—curcumin, resveratrol, anthocyanins, quercetin, salidroside, dietary beetroot juice, pomegranate juice, and adjunctive oral AKL1 treatment—across a total of 894 participants. This systematic review and meta-analysis revealed that, compared to a placebo; ① Curcumin significantly reduced systolic blood pressure (SBP) and improved FEV1(SMD=-0.82, 95%CI -1.53 to -0.11); ② Salidroside was effective in reducing thrombotic markers (TT, D-D), inflammatory factors (TNF-α) and symptom scores (CAT) (p<0.01); ③ Resveratrol significantly downregulates serum TNF-α and IL-8 levels (p=0.003); ④ Anthocyanins may accelerate lung function decline (decreased FEV1/FVC, which needs to be interpreted with caution); ⑤ Other polyphenols (quercetin, pomegranate juice, AKL1, etc.) did not show significant efficacy or insufficient evidence. …”

Table 1_The efficacy of infliximab combined with partial enteral nutrition in the treatment of Crohn’s disease: a cohort study.docx by Chen Huang (202847)

“…</p>Results<p>Among the 176 included patients, 99 (56%) were in the IFX monotherapy group, and 77 (44%) were in the IFX + PEN group. A significantly higher proportion of patients in the IFX + PEN group achieved clinical response (defined as a CDAI decrease ≥70 points) compared to those in the IFX group at 14 weeks (87.01% vs. 74.75%, p = 0.043), as well as a higher proportion achieving endoscopic remission at 54 weeks (84.42% vs. 65.66%, p = 0.005). …”

Study design and plasma viral load. by Zoey K. Wallis (17725175)