DataSheet1_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf by Jianan Zhang (786459)

“…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …”

Supplementary file 1_Efficacy of flavonoids in non-alcoholic fatty liver disease: an updated systematic review and meta-analysis.docx by Qianqian Liu (381114)

“…Flavonoids intervention significantly decreased aspartate aminotransferase (AST), alkaline phosphatase (ALP), alanine aminotransferase (ALT), total cholesterol (TC), steatosis score, body mass index (BMI), triglycerides (TG), fasting blood sugar (FBS), insulin levels and augmented the quantitative insulin sensitivity check index (QUICKI) levels. …”

Table 5_Analysis of epidemiology and nomogram construction for prediction and clinical decision-making in gliomas.xlsx by Yuxin Zhao (637525)

“…Among these factors, age and grade had the most significant impact on prognosis. Furthermore, a predictive nomogram model for 1-/3-/5-year survival rates of gliomas was developed, incorporating the prognostic factors. …”

Data Sheet 1_Analysis of epidemiology and nomogram construction for prediction and clinical decision-making in gliomas.pdf by Yuxin Zhao (637525)

“…Among these factors, age and grade had the most significant impact on prognosis. Furthermore, a predictive nomogram model for 1-/3-/5-year survival rates of gliomas was developed, incorporating the prognostic factors. …”

Table 6_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

Data Sheet 1_Spatial and temporal variability in blue carbon accumulation in the largest salt marsh in British Columbia, Canada.docx by Karen E. Kohfeld (11936879)

“…Boundary Bay (BB) marsh is a 222-ha salt marsh in southern British Columbia, Canada, where construction began in 2023 to enhance the marsh as a natural defense against coastal flooding. …”

Supplementary file 1_EEG activity over ipsilateral and contralateral M1 during simple and complex hand tasks: variations with motor learning.docx by Jun Zhao (59250)

“…However, after 10 training sessions, the electrodes over iM1 activation increased during complex tasks but decreased during simple task for both hands, eliminating significant differences in activation levels between simple and complex tasks. …”

Table 5_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.xlsx by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

Image 1_Antifungal mechanism and transcriptome analysis of Bacillomycin D-C16 against Fusarium oxysporum.tif by Fuxing Lin (7418234)

“…Furthermore, nearly all DEGs related to DNA replication were significantly suppressed. Biochemical assays confirmed these observations: Reduced activities of mitochondrial enzymes [malate dehydrogenase (MDH), isocitrate dehydrogenase (IDH), pyruvate dehydrogenase (PDH), and complexes I–V], decreased mitochondrial membrane potential, and diminished ATP content collectively indicated mitochondrial dysfunction. …”

Data Sheet 1_Soy-based purified ingredient diet affects mouse gut permeability and the microbiome in fragile X mice.pdf by Cara J. Westmark (9302270)

“…Beta-diversity of the cecal microbiome was significantly altered as a function of the four test diets. …”

Table 1_COVID-19’s effect on healthcare disparities: delivery, reimbursement, and premature mortality in residentially segregated populations.docx by Kasabji Feras (21347000)

“…</p>Conclusion<p>The COVID-19 pandemic led to a significant reduction in healthcare utilization across Hungary. …”

DataSheet2_DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer.pdf by Jianan Zhang (786459)

“…Up-regulation of DYNLT3 expression significantly inhibited tumor growth in a nude mouse model, while downregulation of DYNLT3 showed the opposite results. …”

Table_1_RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance.DOCX by Jianmin Chen (330051)

“…CLP caused a significant systolic dysfunction assessed by echocardiography. …”

Data Sheet 1_Explainable machine learning reveals ribosome biogenesis biomarkers in preeclampsia risk prediction.docx by Jingjing Chen (293564)

“…Background<p>Preeclampsia, a hypertensive disorder during pregnancy affecting 2-8% of pregnancies globally, remains a leading cause of maternal and fetal morbidity. …”

Data Sheet 1_Brain injury, endocrine disruption, and immune dysregulation in HIV-positive men who have sex with men with late HIV diagnosis.docx by Yihui He (2936874)

“…A two-way factorial analysis of variance examining the main effects and interactions between groups and neuropsychiatric disorders revealed significant main effects of LD on specific brain regions. …”

Table1_Overexpression of endothelial S1pr2 promotes blood–brain barrier disruption via JNK/c-Jun/MMP-9 pathway after traumatic brain injury in both in vivo and in vitro models.DOCX... by Hongbo Cheng (2848235)

“…</p>Results<p>The expression of S1pr2 significantly increased following TBI in mice. Pharmacological inhibition of S1pr2 alleviated secondary injury with reduced lesion volume, ROS generation, cerebral oedema, neurological deficits, and neuronal apoptosis; BBB disruption was also mitigated, accompanied by reduced degradation of tight junction proteins and decreased induction of matrix metalloproteinases-9 (MMP-9) post-TBI. …”

Data Sheet 1_Mechanistic insights into pyrolysis temperature-dependent lead (Pb) stabilization in phytoremediation residue-derived biochar.docx by Jin Liu (12833)

“…<p>The substantial generation of hazardous, metal-enriched biomass residues poses significant risks of secondary contamination, presenting a critical bottleneck to the broader implementation of phytoremediation that urgently requires effective treatment solutions. …”

Table1_Sucrose synthase gene family in common bean during pod filling subjected to moisture restriction.docx by Norma Cecilia Morales-Elias (20446292)

“….), leaf photosynthesis is significantly reduced under drought conditions. Previous studies have shown that some drought-tolerant cultivars use the pod walls to compensate the decreased photosynthesis rate in leaves by acting as temporary reservoirs of carbohydrates to support seed filling. …”

Figure 4 from Loss of NF1 Accelerates Uveal and Intradermal Melanoma Tumorigenesis, and Oncogenic GNAQ Transforms Schwann Cells by Anne Nathalie Longakit (20658658)

“…<i>Plp1-creERT</i>/+; <i>R26-fs-GNAQ</i>^<i>Q209L</i>/+; +/+ mice. There was a significantly decreased tumor-free survival in <i>Plp1-creERT</i>/+; <i>R26-fs-GNAQ</i>^<i>Q209L</i>/+; <i>Nf1</i>^<i>flox</i>/+ mice. n.s., not significant.…”

Image 1_Prevention of chemotherapy drug-mediated human hair follicle damage: combined use of cooling with antioxidant suppresses oxidative stress and prevents matrix keratinocyte c... by Khalidah Ibraheem (9525220)

“…Optimal cooling at 18°C rescued cell viability, significantly (p < 0.001) restored HF proliferation (42% Ki-67+ cells) and pigmentation, suppressed apoptosis (10% TUNEL+ cells), restored anagen (∼70%) and induced a 2-3-fold increase in hair shaft elongation (p < 0.001), whereas cooling at 26°C was only partially effective. …”