QbD-based co-loading of paclitaxel and imatinib mesylate by protamine-coated PLGA nanoparticles effective on breast cancer cells by Neha Laxane (19851759)

“…</p> <p>A sustained zero-order drug release was obtained for both the formulations.…”

Ecological risk level and area from 2000 to 2020. by Yin Yu (3139023)

“…The results show that (1) the landscape pattern changed visibly from 2000 to 2020, the comprehensive land-use dynamics increased from 8.53% to 9.66%, and the land use dynamics are greatest and change most dramatically on construction sites; (2) the landscape ecological risk level of the study area as a whole showed a declining trend, and 96.82% of the ecological risk plot index decreased, and the risk distribution was dominated by lower risk, medium risk and higher risk areas; (3) landscape ecological risk was spatially positively correlated across all time periods, and the spatial aggregation was gradually weakened, with the distribution of LH and HL areas dispersed and the distribution of HH and LL areas concentrated. …”

Enhanced Anthropogenic Contributions to Marine Aerosols and trace elements Compared to Coastal Regions in Northern China by Yang Zhou (17600586)

“…<p dir="ltr"><a href="" target="_blank">Terrestrial aerosols,</a> transported by westerly winds from Asian continent, continuously deliver both natural and anthropogenic nutrients to downstream marine ecosystems. …”

Data Sheet 1_Comprehensive analysis on the regulatory mechanism of active ingredient accumulation during fermentation process of Massa Medicata Fermentata: microbe and metabolic pr... by Yun Li (692280)

“…</p>Results<p>During the fermentation process, bacterial diversity generally shows an increasing trend, whereas fungal diversity generally shows a decreasing trend. Revealing that the differentially abundant metabolites were primarily categorized into lipids, amino acids and derivatives, phenolic acids, organic acids, flavonoids, lignans and coumarins, nucleotides and derivatives, and alkaloids. …”

Data Sheet 1_Ultra-small curcumin-ruthenium coordination polymer nanodots prevent renal ischemia-reperfusion injury and the progression to chronic kidney disease.docx by Xian Liu (191882)

“…The results indicated that Ru/Cur nanodots effectively eliminated various ROS and demonstrated significant therapeutic effects and biocompatibility in IR-AKI mice, reducing markers of kidney function damage, alleviating renal oxidative stress, and decreasing inflammatory cell infiltration. …”

Area of land use types from 2000 to 2020. by Yin Yu (3139023)

“…The results show that (1) the landscape pattern changed visibly from 2000 to 2020, the comprehensive land-use dynamics increased from 8.53% to 9.66%, and the land use dynamics are greatest and change most dramatically on construction sites; (2) the landscape ecological risk level of the study area as a whole showed a declining trend, and 96.82% of the ecological risk plot index decreased, and the risk distribution was dominated by lower risk, medium risk and higher risk areas; (3) landscape ecological risk was spatially positively correlated across all time periods, and the spatial aggregation was gradually weakened, with the distribution of LH and HL areas dispersed and the distribution of HH and LL areas concentrated. …”

Video 1_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.mp4 by Sofie Vandendriessche (638514)

“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”

Data Sheet 1_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.docx by Sofie Vandendriessche (638514)

“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”

Video 2_Complement activation drives the phagocytosis of necrotic cell debris and resolution of liver injury.mp4 by Sofie Vandendriessche (638514)

“…Importantly, C3 deficiency led to a significant accumulation of necrotic debris and impairment of liver recovery in mice, which was attributed to decreased phagocytosis of debris by recruited neutrophils in vivo. …”

Image_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.pdf by Junjie Jiang (7255706)

“…A multivariable logistic regression model showed that each unit increase in CDAI corresponded to a 14.6% reduction in sleep disorder risk, exhibiting a nonlinear trend where the risk decreased until reaching the inflection point of −0.134. …”

Data Sheet 2_Featured intestinal microbiota associated with hepatocellular carcinoma in various liver disease states.docx by Xiu Sun (8539698)

“…A significant overall difference in alpha diversity was observed across the groups (Chao1: P = 0.010,ϵ²= 0.056; ACE: P = 0.016,ϵ²= 0.049). …”

DataSheet1_Strict biennial lifecycle and anthropogenic interventions affect temporal genetic differentiation in the endangered endemic plant, Pedicularis hallaisanensis.docx by Seongjun Kim (1993465)

“…Other cluster analyses also showed that a microhabitat under historical anthropogenic interventions contained lowered genetic diversity due to a decreased genetic distance between odd-year and even-year flowering cohorts (p < 0.05). …”

Data Sheet 1_Featured intestinal microbiota associated with hepatocellular carcinoma in various liver disease states.pdf by Xiu Sun (8539698)

“…A significant overall difference in alpha diversity was observed across the groups (Chao1: P = 0.010,ϵ²= 0.056; ACE: P = 0.016,ϵ²= 0.049). …”

Table_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx by Junjie Jiang (7255706)

“…A multivariable logistic regression model showed that each unit increase in CDAI corresponded to a 14.6% reduction in sleep disorder risk, exhibiting a nonlinear trend where the risk decreased until reaching the inflection point of −0.134. …”

Data_Sheet_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx by Junjie Jiang (7255706)

“…A multivariable logistic regression model showed that each unit increase in CDAI corresponded to a 14.6% reduction in sleep disorder risk, exhibiting a nonlinear trend where the risk decreased until reaching the inflection point of −0.134. …”

Data_Sheet_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx by Junjie Jiang (7255706)

“…A multivariable logistic regression model showed that each unit increase in CDAI corresponded to a 14.6% reduction in sleep disorder risk, exhibiting a nonlinear trend where the risk decreased until reaching the inflection point of −0.134. …”

Table_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.docx by Junjie Jiang (7255706)

“…A multivariable logistic regression model showed that each unit increase in CDAI corresponded to a 14.6% reduction in sleep disorder risk, exhibiting a nonlinear trend where the risk decreased until reaching the inflection point of −0.134. …”

Raw data_(Submission ID 247694791) by Shengan Zhu (18242155)

“…<p dir="ltr"><a href="" target="_blank"><b>Background:</b></a> Reactive oxygen species (ROS), synthesized by the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (Nox) complex, are vital molecules in biological cells, influencing various physiological processes such as fungal growth, development, and virulence. …”

Image_1_Antioxidants and the risk of sleep disorders: results from NHANES and two-sample Mendelian randomization study.pdf by Junjie Jiang (7255706)

“…A multivariable logistic regression model showed that each unit increase in CDAI corresponded to a 14.6% reduction in sleep disorder risk, exhibiting a nonlinear trend where the risk decreased until reaching the inflection point of −0.134. …”

Ubiquitin degradation of the Ribonuclease H2 subunit B Rnh2B regulates the virulence of <i>Cryptococcus neoformans</i> by Meng-Ru Guo (21375491)

“…Pathogenicity assays revealed that the deletion of <i>RNH2B</i> results in reduced virulence, whereas its overexpression leads to a complete loss of pathogenicity. Longitudinal tracking of fungal infection progression illustrated that mice lungs infected with <i>rnh2B</i>Δ mutants maintained a low yet stable fungal burden, in contrast to a significant reduction in fungal load observed in conjunction with <i>RNH2B</i> overexpression, ultimately leading to complete clearance. …”