Search alternatives:
linear decrease » linear increase (Expand Search)
larger decrease » marked decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
linear decrease » linear increase (Expand Search)
larger decrease » marked decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
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4001
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4002
Effects of Ni<sup>2+</sup> on mitochondrial (A), glycolytic (B), and total (C) ATP production rates in BMDM.
Published 2025“…An <i>F</i> test was used to determine if the slope was significantly different than zero. Data are presented as means ± SEM of 4 and 3 independent experiments for OCR and PER respectively, each performed with sextuplicate samples.…”
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4003
Effects of Ni<sup>2</sup><sup>+</sup> on the mitochondrial and glycolytic energy metabolism of BMDM.
Published 2025“…A double dagger (‡) indicates a significant decrease of OCR (slope = −0.14 ± 0.04, <i>R</i><sup>2</sup> = 0.40, <i>F</i>(1, 22)=15.0, <i>p </i>< 0.001) from 0 to 72 ppm Ni<sup>2+</sup>. …”
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4004
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4005
Heat map showing correlations between comet assay parameters, and warm and cold ischemia times.
Published 2025“…<p>Red values are significant at p < 0.05. Negative values mean that there is a “the more, the less” relationship between the quantities, i.e., as one quantity increases, the other quantity decreases. …”
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4006
Source data for Fig 2.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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4007
Source data for lung metabolomics.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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4008
Source data for Fig 5.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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4009
Source data for Fig 1.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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4010
Flow cytometry gating strategy for MDSC.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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4011
Source data for Fig 3.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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4012
Source data for Fig 4.
Published 2025“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”
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4013
Cyclization Decoded: Engineering Amylomaltase for Efficient α‑Glucan Transformations
Published 2025“…Enzyme kinetics results suggest that the improvement in enzyme performance largely stems from the decrease in enzyme–substrate affinity along the substrate transfer pathway. …”
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4014
Participant characteristics by village.
Published 2025“…We hypothesized that farmers with greater market-based wealth and more farming experience would have higher odds of adaptation. …”
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4015
Description of the variables and data sources.
Published 2025“…Using a micro-founded measure of trade costs derived from the gravity model, we find that Cambodia’s average trade costs decreased by 35.43 percent between 1993 and 2019. …”
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4016
Descriptive statistics of the variables.
Published 2025“…Using a micro-founded measure of trade costs derived from the gravity model, we find that Cambodia’s average trade costs decreased by 35.43 percent between 1993 and 2019. …”
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4017
Eq 13.
Published 2025“…Using a micro-founded measure of trade costs derived from the gravity model, we find that Cambodia’s average trade costs decreased by 35.43 percent between 1993 and 2019. …”
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4018
School learning model dispositions data.
Published 2025“…P-values<0.050 were considered significant. From 2019 to 2021, reported persistent feelings of sadness/hopelessness (2019 = 36.3%, 2021 = 41.3%), seriously considering suicide (17.0-18.7%), making suicide plan(s) (14.2-16.9%), and experiencing sexual dating violence in past 12 months (6.7-7.8%) increased significantly, while alcohol use (22.5-17.1%), binge drinking (8.5-6.2%), and marijuana use (20.2-14.3%) in past 30 days, ever prescription opioid misuse (16.0-13.2%), and gun-carrying (5.5-4.5%), physical fighting (22.3-17.3%), and any sexual violence (11.3-10.4%) in past 12 months decreased significantly. …”
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4019
Cataract induction does not affect hunting behaviour in optimal light conditions (left panels) but causes impairments in challenging light environments (right panels).
Published 2025“…Similarly, under bright and UV light, we did not detect differences in hunting success (E,G; <i>n</i><sub><i>control</i></sub> = 12, <i>n</i><sub><i>lens3RNAi </i></sub>= 23, <i>p</i><sub>horizontal</sub> = 0.28, <i>p</i><sub>vertical</sub> = 0.23), but observed a weak (nonsignificant) decrease in the hunting success of treatment individuals under dim white light (F,H; <i>n</i><sub><i>control</i></sub> = 13, <i>n</i><sub><i>lens3RNAi </i></sub>= 22, <i>p</i><sub>horizontal</sub> = 0.22, <i>p</i><sub>vertical</sub> = 0.42).…”
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4020
Probing Field Cancerization in the Gastrointestinal Tract Using a Hybrid Raman and Partial Wave Spectroscopy Microscope
Published 2025“…In the normal tissue of L2-IL1B mice, we demonstrate a statistically significant increase (<i>p</i> < 0.001) in Raman band intensities associated with free amino acids and a decrease in bands associated with lipids (<i>p</i> < 0.005) and carotenoids (<i>p</i> < 0.001) compared to healthy controls. …”