High variability in the reproducibility of key hemodynamic responses to head-up tilt by Heidi Bouquin (17563521)

“…<p dir="ltr">Increased blood pressure upon standing is considered a cardiovascular risk factor. We investigated the reproducibility of changes in aortic blood pressure, heart rate, stroke volume, cardiac output, and systemic vascular resistance during three passive head-up tilts (HUT) in 223 participants without cardiovascular medications (mean age 46 years, BMI 28 kg/m2, 54% male). …”

Bouquin et al. - High variability in the reproducibility of key hemodynamic responses to head-up tilt by Heidi Bouquin (17563521)

“…<p dir="ltr">Increased blood pressure upon standing is considered a cardiovascular risk factor. We investigated the reproducibility of changes in aortic blood pressure, heart rate, stroke volume, cardiac output, and systemic vascular resistance during three passive head-up tilts (HUT) in 223 participants without cardiovascular medications (mean age 46 years, BMI 28 kg/m2, 54% male). …”

Bouquin et al. - High variability in the reproducibility of key hemodynamic responses to head-up tilt by Heidi Bouquin (17563521)

“…<p dir="ltr">Increased blood pressure upon standing is considered a cardiovascular risk factor. We investigated the reproducibility of changes in aortic blood pressure, heart rate, stroke volume, cardiac output, and systemic vascular resistance during three passive head-up tilts (HUT) in 223 participants without cardiovascular medications (mean age 46 years, BMI 28 kg/m2, 54% male). …”

Repetitive stress induces a reduction in sound-evoked activity that develops as the stressor becomes chronic. by Ghattas Bisharat (20706928)

“…(b) Change in activity across sessions per tracked cell in response to 40, 60, and 70 dB white noise. We found a negative slope in most cells especially for mid-intensities, indicating a decrease in activity as the stress becomes chronic (<i>t</i> test for 40 dB <i>p</i> = 0.36, for 60 dB <i>p</i> = 9.3 × 10⁻¹², and for 70 dB <i>p</i> = 0.00750). …”

Exposure to environments with different norms changes participants’ behavior. by Claire Lugrin (21156528)

“…Each participant faced one of four environments. We varied the type of norm that was manipulated (descriptive versus prescriptive norms) and the direction of the change (increased or decreased prosociality). …”

Table 1_The impact of prebiotics, probiotics and synbiotics on the prevention and treatment of atopic dermatitis in children: an umbrella meta-analysis.docx by Lifeng Wang (121568)

“…The treatment resulted in a significant decrease in SCORAD score among children with moderate to severe AD, but not in subjects with mild AD.…”

Data_Sheet_1_Finger-specific effects of age on tapping speed and motor fatigability.docx by Caroline Heimhofer (19735888)

“…</p>Results<p>We found that the maximal tapping speed differed significantly between young (18–30 years, n = 194) and aged (50–70 years, n = 176), whereas the fatigability-induced relative decrease in movement speed did not differ between the age groups (average decrease: 17.0% ± 6.9% (young) vs. 16.5% ± 7.5% (aged) decrease). …”

Data Sheet 1_Large scale atmospheric conditions favoring storm surges in the North and Baltic Seas and possible future changes.docx by Nils H. Schade (21676022)

“…In contrast, a significant decrease of easterly effective winds is projected for all four locations at the Baltic Sea coast. …”

Data Sheet 1_Effects of therapeutic horsemanship on caregiver stress scores of children with autism.pdf by Danielle C. Barron (21634196)

“…Semi-structured interviews were performed once during the semester and transcripts were analyzed using thematic analysis.</p>Results<p>We observed caregivers experienced a statistically significant decrease (p=0.03) in their stress levels over a single semester of TH participation demonstrated by a reduction in DASS-21 stress subcategory (pre intervention mean 12.77 (SD = 9.95), post-intervention mean 8.62 (SD = 10.98). …”

Data Sheet 2_Effects of therapeutic horsemanship on caregiver stress scores of children with autism.pdf by Danielle C. Barron (21634196)

“…Semi-structured interviews were performed once during the semester and transcripts were analyzed using thematic analysis.</p>Results<p>We observed caregivers experienced a statistically significant decrease (p=0.03) in their stress levels over a single semester of TH participation demonstrated by a reduction in DASS-21 stress subcategory (pre intervention mean 12.77 (SD = 9.95), post-intervention mean 8.62 (SD = 10.98). …”

Video1_One-year real-world experience with mavacamten and its physiologic effects on obstructive hypertrophic cardiomyopathy.mov by Daniel Seung Kim (19510291)

“…Moreover, in our center's experience, neither arrhythmia burden, nor contractility have worsened in the vast majority of patients: we note a clinically insignificant mean decrease in left ventricular ejection fraction (LVEF), with only two patients requiring temporary mavacamten discontinuance for LVEF < 50%. …”

pone.0331193.t003 - by Carol Kotliar (22351525)

“…The global cognitive score increased by 4.6 points (5%) in the intervention group compared to a decrease of 0.5 points in the control group (p < 0.001). …”

Baseline characteristics by group. by Carol Kotliar (22351525)

“…The global cognitive score increased by 4.6 points (5%) in the intervention group compared to a decrease of 0.5 points in the control group (p < 0.001). …”

Data Sheet 1_Pregnancy and contraceptive use among participants of childbearing potential in the HVTN 705 HIV vaccine trial in Southern Africa.docx by Pamela Mda (20390050)

“…Nevertheless, some pregnancies occur in almost all studies. We examined contraceptive use, pregnancy incidence, and the relationship between pregnancy and HIV seroconversion in one HIV vaccine trial.…”

Beta cell function derived from routine clinical measures reports and predicts treatment response to immunotherapy in recent-onset type 1 diabetes. by Michelle So (400874)

“…Beta2 score, derived from fasting glucose, C-peptide, HbA1c and insulin dose at 12 weeks, was optimal for predicting QRS>0 following one year of treatment with baricitinib and the other immunotherapies (areas under receiver-operator curve 0.864 and 0.765 respectively). A 6.2% decrease in Beta2 score at week 12 predicted significant improvement in HbA1c (-0.6% or -6 mmol/mol) and insulin use (-0.26 units/kg/day) in combined data from the rituximab, abatacept and anti-thymocyte globulin trials.…”

Data Sheet 1_Hemodynamic changes and their relationship with white matter hyperintensities in CSVD patients with cognitive impairment: a 4D flow study.pdf by Jiajun Cao (11560062)

“…There was a moderately positive correlation between MMSE, MoCA score and flow rate, flow velocity, and WSS (r = 0.226–0.544, all P < 0.05), and a moderately negative correlation between MMSE, MoCA score and PI, RI (r = −0.230 to −0.406, all P < 0.05). Multiple linear regression indicated that, the flow rate and mean velocity in venous sinuses (β = −0.472 to −0.381, all P < 0.05) and the WSS in arterial segments (β = −0.771 to −0.441, all P < 0.05) had independently negative association with WMH burden; Meanwhile, a significant positive relationship was found between PI in arterial segments and specific-distributed WMH (PVWMH and S-CC WMH) (β = 0.239 to 0.356, all P < 0.05).…”

Comparative Analysis of Gut Microbiota in Collegiate Swimmers Following Changes in Exercise by Jarrad Hampton-Marcell (695263)

“…Peak training volume, measured as swimming distance, decreased significantly during the study period from 32.6 ± 4.8 km/wk to 11.3 ± 8.1 km/wk (ANOVA, p < 0.05); however, body composition showed no significant changes. …”

Image 1_Evaluation of clopidogrel impact on canine platelet function using flow cytometry and thromboelastography platelet mapping.tif by Eunchae Yoon (21487805)

“…Flow cytometry confirmed the marked inhibition of platelet activation, with significant decreases in the percentage of CD62P positive platelets and the mean fluorescence intensity under ADP and epinephrine stimulation (p < 0.05). …”

Table 1_Single and consecutive 10-day remote ischemic preconditioning modify physical performance, post-exercise exerkine levels, and inflammation.docx by Magdalena Kochanowicz (20153682)

“…Similarly, a significant 15.5% (p < 0.05) decrease in the IL-6 concentration 120 min after the WAnT was observed only in the consecutive 10-day RIPC protocol, as well as a 12.2% (p < 0.01) increase in oncostatin M 60 min after the WAnT.…”

Table 1_Uncaria tomentosa extract exerts antimicrobial activity against boar seminal bacteria and influences sperm resilience under different conditions.xlsx by Maria Scaringi (18815462)

“…During semen storage, the extract did not show any cytotoxicity, and mean values of some sperm parameters were higher than the control group, although not significant (p > 0.05). …”