Supplementary Material for: Association of MTHFR gene with type 2 diabetes mellitus: A case-control study and meta-analysis by figshare admin karger (2628495)

“…Results: In case-control study at the C677T(rs1801133), we found that compared with the AA genotype, GG + GA genotype was associated with an increased risk of T2DM (OR=1.605; 95% CI: 1.229–2.095; P=0.001); compared with the GG/GA genotype, AA genotype was associated with a decreased risk of T2DM (OR=0.620; 95% CI: 0.450–0.855; P=0.004; OR=0.625; 95% CI: 0.470–0.830; P=0.001). …”

Causal associations between kidney function and aortic valve stenosis: a bidirectional Mendelian randomization analysis by Wanqian Pan (18147420)

“…In addition, the evidence did not support a significant causal association of AVS on kidney function.…”

Table 2_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Analyzing the malaria burden will aid in designing prevention, control, and eradication strategies based on scientific evidence.</p>Methods<p>We retrieved data from the 2021 Global Burden of Disease (GBD) database to assess the malaria burden in the Comoros in 2021, stratified by sex and age. …”

Table 1_The impact of climate change on medicinal plants and natural products: A scoping review.pdf by Marce Inggritha Takubessi (22671905)

“…However, climate change has threatened their supply and sustainability. In this review, we map the current state of research on how climate change affects medicinal plants, focusing on ecological shifts, traditional uses, changes in bioactive metabolites, and adaptation strategies.…”

DataSheet3_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx by Yiyi Zuo (19945293)

“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”

Table 9_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Analyzing the malaria burden will aid in designing prevention, control, and eradication strategies based on scientific evidence.</p>Methods<p>We retrieved data from the 2021 Global Burden of Disease (GBD) database to assess the malaria burden in the Comoros in 2021, stratified by sex and age. …”

Table 10_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Analyzing the malaria burden will aid in designing prevention, control, and eradication strategies based on scientific evidence.</p>Methods<p>We retrieved data from the 2021 Global Burden of Disease (GBD) database to assess the malaria burden in the Comoros in 2021, stratified by sex and age. …”

DataSheet2_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.xlsx by Yiyi Zuo (19945293)

“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”

Table 4_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Analyzing the malaria burden will aid in designing prevention, control, and eradication strategies based on scientific evidence.</p>Methods<p>We retrieved data from the 2021 Global Burden of Disease (GBD) database to assess the malaria burden in the Comoros in 2021, stratified by sex and age. …”

Data Sheet 1_Decoding the hypoxia-exosome-immune triad in OSA: PRCP/UCHL1/BTG2-driven metabolic dysregulation revealed by interpretable machine learning.zip by Weilong Ye (12984647)

“…By integrating transcriptomic data, machine learning, and immune analysis, we uncover an “exosome-immune” axis in OSA pathophysiology.…”

Table 1_Impact of hearing loss on brain signal variability in older adults under different auditory load conditions.docx by Songjian Wang (18173353)

“…</p>Results<p>Results revealed that the brain signal variability increased with higher SNR loads in healthy older adults, indicating enhanced neural resource allocation with the SNR load. In contrast, we found that hearing loss reduced brain signal variability during speech recognition tasks, especially in noisy conditions, in the mild hearing loss and moderate to severe hearing loss groups, possibly indicating decreased neural processing efficiency. …”

Table 5_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Analyzing the malaria burden will aid in designing prevention, control, and eradication strategies based on scientific evidence.</p>Methods<p>We retrieved data from the 2021 Global Burden of Disease (GBD) database to assess the malaria burden in the Comoros in 2021, stratified by sex and age. …”

DataSheet1_Dysregulation of the 3β-hydroxysteroid dehydrogenase type 2 enzyme and steroid hormone biosynthesis in chronic kidney disease.pdf by Yiyi Zuo (19945293)

“…</p>Results<p>Metabolic characteristics revealed significant shifts in CKD, with 61 metabolites increased and 65 metabolites decreased, highlighting the disruption in steroid hormone biosynthesis pathways influenced by HSD3B2. …”

Data_Sheet_1_Liver cirrhosis is a risk-factor for Pneumocystis jirovecii associated mortality.pdf by Georg Peschel (14005905)

“…There was a significant correlation of Meld score and mortality (r = 0.612, p < 0.001).…”

Table 3_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Analyzing the malaria burden will aid in designing prevention, control, and eradication strategies based on scientific evidence.</p>Methods<p>We retrieved data from the 2021 Global Burden of Disease (GBD) database to assess the malaria burden in the Comoros in 2021, stratified by sex and age. …”

Table 1_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Analyzing the malaria burden will aid in designing prevention, control, and eradication strategies based on scientific evidence.</p>Methods<p>We retrieved data from the 2021 Global Burden of Disease (GBD) database to assess the malaria burden in the Comoros in 2021, stratified by sex and age. …”

Table 11_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Analyzing the malaria burden will aid in designing prevention, control, and eradication strategies based on scientific evidence.</p>Methods<p>We retrieved data from the 2021 Global Burden of Disease (GBD) database to assess the malaria burden in the Comoros in 2021, stratified by sex and age. …”

Table 8_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Analyzing the malaria burden will aid in designing prevention, control, and eradication strategies based on scientific evidence.</p>Methods<p>We retrieved data from the 2021 Global Burden of Disease (GBD) database to assess the malaria burden in the Comoros in 2021, stratified by sex and age. …”

Data_Sheet_1_A novel chimeric endolysin Cly2v shows potential in treating streptococci-induced bovine mastitis and systemic infections.docx by Shuang Wang (46453)

“…With the development of multidrug-resistant bacteria, it is crucial to develop novel antibiotic alternatives. Here, we constructed a novel chimeric endolysin, Cly2v, which comprises the Ply2741 CHAP domain (1-155aa) and the PlyV12 CBD domain (146-314aa). …”

Table 7_Burden of malaria in the Comoros, 1990–2021: findings from the global burden of disease study 2021.xlsx by Sheng Zhou (66217)

“…Analyzing the malaria burden will aid in designing prevention, control, and eradication strategies based on scientific evidence.</p>Methods<p>We retrieved data from the 2021 Global Burden of Disease (GBD) database to assess the malaria burden in the Comoros in 2021, stratified by sex and age. …”