Data Sheet 1_Identification of potential biomarkers for lung adenocarcinoma: a study based on bioinformatics analysis combined with validation experiments.zip by Chuchu Zhang (2562154)

“…Among them, only TGFBR2 had a significant causal relationship with LUAD (p=0.04, b=−0.06), and it is a protective factor for LUAD. …”

DataSheet1_Glioma-associated oncogene homolog 1 in breast invasive carcinoma: a comprehensive bioinformatic analysis and experimental validation.docx by Teng Qi (278739)

“…</p>Results<p>The findings reveal dysregulated expression of GLI1 in numerous cancers, with a significant decrease observed in BRCA. High GLI1 expression indicated better survival outcomes and was correlated with the age and stage of BRCA patients. …”

Flowchart of study population. by Yan Zeng (120271)

“…Additionally, when PLT-min levels were categorized into tertiles as <95 × 10⁹/L (group 1), 95–160 × 10⁹/L (group 2), and >160 × 10⁹/L (group 3), a decrease in PLT-min levels was also associated with an increasing trend in hospital mortality rate. …”

Assessing the Causal Role of Walking Pace and Hand Grip Strength with Chronic Obstructive Pulmonary Disease Hospital: A Mendelian Randomization Study by Lu Wang (45927)

“…We also found a significant correlation between weaker hand grip and reduced lung function, especially FVC. …”

Table 2_Revealing fitness and virulence determinants of hypervirulent Klebsiella pneumoniae during infection in Galleria mellonella using a transposon library.xlsx by Lisheng Xiao (15919517)

“…<p>Klebsiella pneumoniae infections represent a significant public health concern. Despite their clinical relevance, the genetic determinants underlying bacterial fitness and virulence remain incompletely characterized. …”

Table 1_Revealing fitness and virulence determinants of hypervirulent Klebsiella pneumoniae during infection in Galleria mellonella using a transposon library.xlsx by Lisheng Xiao (15919517)

“…<p>Klebsiella pneumoniae infections represent a significant public health concern. Despite their clinical relevance, the genetic determinants underlying bacterial fitness and virulence remain incompletely characterized. …”

Data_Sheet_1_The total joint arthroplasty care patterns in China during the COVID-19 pandemic: a multicenter cohort study.PDF by Tianyi Zhang (87298)

“…Multivariate regression and propensity score matching (PSM) analyses were used to assess the impact of the COVID-19 pandemic on hospital complications, readmissions at 30 days, LOS, and costs at the patient level.</p>Results<p>A total of 752,477 inpatients undergoing TJA in the prepandemic period, 1,291,248 in the pandemic period, with an average 13.1% yearly decrease in the volume of TJA during the pandemic. …”

Impact of structural connectivity on dynamic functional connectivity in stimulated regions in right DLPFC-tDCS protocol (F4a-Fp1c). by Yanqing Dong (8829548)

“…Warmer colors correspond to an increase in functional connectivity, while cooler colors correspond to a decrease in functional connectivity. The color bars indicate statistical t-values (<i>p</i> < 0.05).…”

Table 1_Global burden of childhood otitis media attributable to secondhand smoke from 1990 to 2021: a systematic analysis of the global burden of disease study 2021.docx by Bei Li (90587)

“…Background<p>Childhood otitis media is significantly influenced by exposure to secondhand smoke (SHS), posing a considerable challenge to pediatric health. …”

Table 2_Integrative physiological, biochemical, and metabolomic analyses reveal complex drought and zinc stress tolerance in a novel Miscanthus hybrid.xlsx by Monirul Islam (283000)

“…Drought, Zn, and combination D + Zn stress treatments increased proline accumulation (p < 0.0001), antioxidant enzyme activities (p < 0.05), including superoxide dismutase (SOD), ascorbate peroxidase (APX), glutathione reductase (GR), and decreased levels of MDA. Overall, these responses indicate that the Miscanthus GRC10 hybrid displays a complex response to drought and Zn stresses that confers growth resilience in Zn-contaminated and drought-prone lands.…”

Table 3_Integrative physiological, biochemical, and metabolomic analyses reveal complex drought and zinc stress tolerance in a novel Miscanthus hybrid.xlsx by Monirul Islam (283000)

“…Drought, Zn, and combination D + Zn stress treatments increased proline accumulation (p < 0.0001), antioxidant enzyme activities (p < 0.05), including superoxide dismutase (SOD), ascorbate peroxidase (APX), glutathione reductase (GR), and decreased levels of MDA. Overall, these responses indicate that the Miscanthus GRC10 hybrid displays a complex response to drought and Zn stresses that confers growth resilience in Zn-contaminated and drought-prone lands.…”

Table 1_Integrative physiological, biochemical, and metabolomic analyses reveal complex drought and zinc stress tolerance in a novel Miscanthus hybrid.xlsx by Monirul Islam (283000)

“…Drought, Zn, and combination D + Zn stress treatments increased proline accumulation (p < 0.0001), antioxidant enzyme activities (p < 0.05), including superoxide dismutase (SOD), ascorbate peroxidase (APX), glutathione reductase (GR), and decreased levels of MDA. Overall, these responses indicate that the Miscanthus GRC10 hybrid displays a complex response to drought and Zn stresses that confers growth resilience in Zn-contaminated and drought-prone lands.…”

Efficacy of Shenkang Injection combined with renin-angiotensin-aldosterone system blockers in diabetic nephropathy: a systematic review and meta-analysis of randomized controlled t... by Xinyue Zhang (271120)

“…Urinary protein excretion rate (UPER), serum creatinine (SCr), blood urea nitrogen (BUN), 24-hour urinary protein (24h-UTP), total cholesterol (TC), and triglyceride (TG) levels all significantly decreased in the combination group. Subgroup analysis showed that patients aged ≤55 years had greater reductions in SCr (WMD −25.62, 95% CI −29.41 to −21.83) and BUN (WMD −2.51, 95% CI −2.75 to −2.27). …”

Microbial Alliances: Unveiling the Effects of a Bacterial and Fungal Cross-Kingdom SynCom on Bacterial Dynamics, Rhizosphere Metabolites, and Soybean Resilience in Acidic Soils by Zhongling Wen (13878743)

“…RhRi also enhanced soil enzyme activity (urease, phosphatases), which resulted in an increase in nitrogen and phosphorus availability and a decrease in rhizosphere toxicity. These alterations enhanced plant resilience, soil structure, and microbial diversity. …”

Supplementary file 1_Healthy lifestyle moderates the association between recent negative life events and depressive symptoms: a cross-sectional study.docx by Yang Yang (45629)

“…</p>Conclusion<p>In this cross-sectional study, healthy lifestyle act as a moderating role and adopting a greater number of healthy lifestyles was associated with a lower likelihood of depressive symptoms, and mitigated the association between RNLEs and depressive symptoms.…”

Table 1_Association between sarcopenia and outcomes of surgically treated oral squamous cell carcinoma: a systematic review and meta‐analysis.docx by Kai Luo (769190)

“…Background<p>Sarcopenia is a significant predictor of perioperative adverse outcomes for a variety of malignancies and has significant negative effects on surgical and oncology outcomes. …”

Table 1_Loneliness and mental burden among German medical students during the fading COVID-19 pandemic: a mixed-methods approach.docx by Marvik Leich (20930363)

“…Lower peer connectedness emerged as the sole significant factor associated with loneliness in summer 2022. …”

Table 1_Thymoquinone/β-N-acetylglucosaminidase, a novel plant-derived combination, inhibited quorum sensing signaling pathways and disrupted biofilm in Staphylococcus aureus.docx by Adel Attia M. Ahmad (16729177)

“…Notably, NAGase, whether used alone or in conjunction with TQ, led to a decrease in the expression of the atl, icaA, and agr genes.…”

Supplementary Material for: Abnormal Magnetic Resonance Imaging in the Medial Prefrontal Cortex Following Prenatal Alcohol Exposure and Placental Insufficiency in a Preclinical Mod... by figshare admin karger (2628495)

“…In the corpus callosum, the prenatal exposure/insult significantly decreased the AD (p<0.05; PAE+PI AD: 5.00x10-4 ± 4.60x10-5 mm2/s). …”

Supplementary Material for: Underwater Clip Closure versus Conventional Clip Closure following Endoscopic Submucosal Dissection in Colorectal Lesions: A First Comparative Study by figshare admin karger (2628495)

“…Multiple regression analysis identified both resection area (p < 0.001) and closure method (p = 0.002) as independent factors affecting closure time. Conclusion UCC may decrease the time required for post-ESD closure of colorectal lesions measuring ≤5 cm, while using a comparable number of clips to CCC, with no serious complications.…”