Image1_Alhagi maurorum extract in combination with lytic phage cocktails: a promising therapeutic approach against biofilms of multi-drug resistant P. mirabilis.JPEG by Arezoo Mirzaei (11921191)

“…<p>Antimicrobial resistance (AMR) poses a significant global threat to public health systems, rendering antibiotics ineffective in treating infectious diseases. …”

Image 1_Association of inflammatory biomarkers with new functional morbidity at hospital discharge in children who survive severe sepsis.pdf by Mallory A. Perry-Eaddy (20842868)

“…</p>Results<p>New functional morbidity occurred in 38 children (32%) and was associated with increased plasma levels of interleukin (IL)-6, IL-18, sIL-2Ra, MCP1, IL-8 (CXCL8), sIL-1RII, IL-10, MIP1a, and IL-2r and decreased RANTES (CCL5) (p < .001) at all three timepoints. …”

S1 Dataset - by Edgar Innocent Guma (20370676)

“…<div><p>Interpersonal violence is a significant public health and human rights concern. …”

Data Sheet 1_Photodynamic therapy with a novel photosensitizer inhibits DSS-induced ulcerative colitis in rats via the NF-κB signaling pathway.docx by Yumei Rong (11589031)

“…Mechanism studies demonstrated that LD₄-PDT could inhibit the NF-κB signaling pathway, downregulated the expression of the inflammatory factors’ tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and myeloperoxidase (MPO), increased the contents of glutathione (GSH) and superoxide dismutase (SOD) and decreased the content of malondialdehyde (MDA). Additionally, analysis of gut microbiota revealed that LD₄-PDT treatment could decrease the abundance of the Proteobacteria phylum in fecal samples, while no significant differences were observed in the Firmicutes, Bacteroidetes, or Actinobacteria phyla among the three groups using 16S rRNA analysis.…”

Characteristics of the study participants. by Michał Wendt (17601180)

“…No significant changes were observed in the control group, although a trend toward lower pain levels was noted in the experimental group after intervention.…”

Data Sheet 1_Impact of a moderate-intensity aerobic exercise intervention on systemic and uterine natural killer cells in women with unexplained recurrent pregnancy loss.pdf by Aysel Gurbanova (21477746)

“…NK cell function was assessed with degranulation assays and intracellular staining of interferon-γ (IFN-γ), perforin and granzyme-B in a subgroup of women due to lower availability of samples (n=12).…”

Data Sheet 1_Comparison of intravascular imaging, physiological assessment and angiography for coronary revascularization in acute coronary syndrome: a systematic review and networ... by Xuan-Yan Liu (19362096)

“…Patients who received quantitative flow ratio (QFR)-guided PCI experienced lower all-cause mortality (RR: 0.25; 95%CI: 0.07–0.92) vs. those receiving angiography. …”

In Situ Fluorescence Imaging of Oxygen Evolution on Epitaxial Perovskite Films with Composition Gradients by Daniel J. Zheng (16447930)

“…To date, most OER catalyst discovery has relied on human-driven approaches that have led to an understanding of only a small proportion of all possible materials. In recent years, the advent of high-throughput virtual screening and machine learning has significantly increased the space that has been explored, but methods for experimentally validating the OER activities at scale are still limited and challenging. …”

In Situ Fluorescence Imaging of Oxygen Evolution on Epitaxial Perovskite Films with Composition Gradients by Daniel J. Zheng (16447930)

“…To date, most OER catalyst discovery has relied on human-driven approaches that have led to an understanding of only a small proportion of all possible materials. In recent years, the advent of high-throughput virtual screening and machine learning has significantly increased the space that has been explored, but methods for experimentally validating the OER activities at scale are still limited and challenging. …”

Variability in performance and response to task dynamics. by Daniel Ramandi (10047543)

“…(B) The analysis of trajectory variability, quantified as DTW distance of consecutive trials, showed a non-significant trend towards greater variability in zQ175 mice, peaking later compared to WT mice (RM two-way ANOVA, genotype p = 0.070 F(1, 20) = 3.660, trial p = 0.0005 F(4.291, 85.82) = 5.351, interaction p = 0.542 F(19, 380) = 0.9329). …”

Key safety measures including adverse events. by Anuja Dokras (8679261)

“…<div><p>Background</p><p>The risk-to-benefit ratio of using combined oral contraceptive pills (COCPs) and/or metformin for comprehensive management of polycystic ovary syndrome (PCOS) in women with obesity is unclear. As there is a lack of robust evidence on the impact of these first-line medications on cardiovascular disease (CVD) risk, we compared the effect of COCPs, metformin or both on prevalence of metabolic syndrome (MetS) in participants with hyperandrogenic PCOS and hypothesized that COCPs would increase prevalence of MetS while metformin would decrease prevalence of MetS.…”

Table 1_Efficacy and safety of cadonilimab combined with AG chemotherapy in patients with unresectable locally advanced or metastatic pancreatic ductal adenocarcinoma: a retrospect... by Wenke Qin (20390989)

“…</p>Results<p>The disease control rate (DCR) reached 85.7%, and the objective response rate (ORR) was 14.3%; the median progression-free survival (mPFS) was 7.87 months, and the median overall survival (mOS) was 11.45 months. Among patients with a decrease in CA19-9, the median overall survival was significantly prolonged (12.92 vs 8.89 months, P = 0.027); patients with a platelet-lymphocyte ratio (PLR) ≤ 165.62 had a significantly better mOS (12.37 vs 8.74 months, P = 0.025). …”

Data Sheet 1_The sigma factor σ54 (rpoN) functions as a global regulator of antibiotic resistance, motility, metabolism, and virulence in Clostridioides difficile.docx by Ying Yang (24175)

“…<p>Clostridioides difficile, a major cause of antibiotic-associated diarrhea and pseudomembranous colitis, is increasingly resistant to antibiotics and poses a significant threat due to its regulated virulence. …”

Table 1_Modeling the advective supply of Calanus finmarchicus to Stellwagen Bank as an indicator of sand lance foraging habitat, and the climate vulnerability of a National Marine... by Cameron R. S. Thompson (20622296)

“…Years with stronger MCC flow showed higher connectivity and a greater potential supply of C. finmarchicus particles to Stellwagen Bank. …”

Table 2_Modeling the advective supply of Calanus finmarchicus to Stellwagen Bank as an indicator of sand lance foraging habitat, and the climate vulnerability of a National Marine... by Cameron R. S. Thompson (20622296)

“…Years with stronger MCC flow showed higher connectivity and a greater potential supply of C. finmarchicus particles to Stellwagen Bank. …”

Table 3_Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective... by Rongrong Lu (322302)

“…Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.027). …”

Table 1_Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective... by Rongrong Lu (322302)

“…Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.027). …”

Table 2_Association between platelet-to-red cell distribution width ratio and all-cause mortality in critically ill patients with non-traumatic cerebral hemorrhage: a retrospective... by Rongrong Lu (322302)

“…Following adjustment for confounding factors, patients with elevated PRR exhibited a significantly decreased risk of in-hospital death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.006) and ICU death (HR, 0.98; 95% CI, 0.96–0.99; p = 0.027). …”

Data Sheet 1_Mind the road: attention related neuromarkers during automated and manual simulated driving captured with a new mobile EEG sensor system.pdf by Joanna Elizabeth Mary Scanlon (13913817)

“…Background<p>Decline in vigilance due to fatigue is a common concern in traffic safety. Partially automated driving (PAD) systems can aid driving but decrease the driver's vigilance over time, due to reduced task engagement. …”

A lineage 1 branch porcine reproductive and respiratory syndrome virus live vaccine candidate provides broad cross-protection against HP-like PRRSV in piglets by Chao Li (145513)

“…HP-PRRSV has undergone significant genetic variation following nearly two decades of evolution and has transformed into a subtype referred to as HP-like PRRSV, which also exhibits high pathogenicity. …”