Data Sheet 1_Comprehensive analysis of metabolism-related genes in sepsis reveals metabolic–immune heterogeneity and highlights GYG1 as a potential therapeutic target.csv حسب Jie Zheng (31208)

"…In vivo, Gyg1 was markedly upregulated in septic mice, and LNP-mediated siRNA knockdown of Gyg1 significantly improved survival in the LPS model. Mechanistically, Gyg1 knockdown significantly reduced glycogen content in myeloid cells, attenuated IL-6 and TNF-α production, alleviated LPS-induced neutrophil, and modestly decreased CD40 expression in monocytes and dendritic cells. …"

Data Sheet 1_Thymoquinone/β-N-acetylglucosaminidase, a novel plant-derived combination, inhibited quorum sensing signaling pathways and disrupted biofilm in Staphylococcus aureus.p... حسب Adel Attia M. Ahmad (16729177)

"…Notably, NAGase, whether used alone or in conjunction with TQ, led to a decrease in the expression of the atl, icaA, and agr genes.…"

Table1_Asparagus officinalis L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.pdf حسب Ziwei Fang (10115899)

"…Asparagus officinalis extract treatment for 4 weeks resulted in a significant reduction in tumor growth in Lkb1^fl/flp53^fl/fl mice under both obese and lean conditions, with a decrease in Ki-67 and vascular endothelial growth factor expression and an increase in Bip expression in endometrial tumors.…"

Table2_Asparagus officinalis L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.pdf حسب Ziwei Fang (10115899)

"…Asparagus officinalis extract treatment for 4 weeks resulted in a significant reduction in tumor growth in Lkb1^fl/flp53^fl/fl mice under both obese and lean conditions, with a decrease in Ki-67 and vascular endothelial growth factor expression and an increase in Bip expression in endometrial tumors.…"

Data Sheet 1_Impact of fatigue in Crohn's disease is negatively related to resting state functional connectivity between the superior parietal lobule and parahippocampal gyrus/hipp... حسب Theresa A. McIver (21178337)

"…Moderation analyses revealed a significant interaction between disease activity, total fatigue, and functional connectivity of the right superior parietal lobule and left anterior parahippocampal gyrus (ΔR² = 0.058, F = 5.445, p = 0.0245). …"

Table 1_A peptide mimic of SOCS1 modulates equine peripheral immune cells in vitro and ocular effector functions in vivo: implications for recurrent uveitis.docx حسب Lauren Stewart Stafford (17937497)

"…</p>Results<p>Following SOCS1-KIR pretreatment, cell proliferation significantly decreased in control, but not ERU-derived PBMCs. …"

Data Sheet 1_Efficacy and safety of vonoprazan-amoxicillin dual therapy versus bismuth-containing quadruple therapy for patients with Helicobacter pylori infection: a meta-analysis... حسب Xiao Li (107004)

"…Furthermore, VA has lower cost compared to BQT.</p>Conclusion<p>Our findings indicated that VA dual therapy provided a higher eradication rate, enhanced compliance, decreased adverse events, and lowered cost relative to BQT for patients with H. pylori infection.…"

Data Sheet 2_Efficacy and safety of vonoprazan-amoxicillin dual therapy versus bismuth-containing quadruple therapy for patients with Helicobacter pylori infection: a meta-analysis... حسب Xiao Li (107004)

"…Furthermore, VA has lower cost compared to BQT.</p>Conclusion<p>Our findings indicated that VA dual therapy provided a higher eradication rate, enhanced compliance, decreased adverse events, and lowered cost relative to BQT for patients with H. pylori infection.…"

Data Sheet 1_Induction immunochemotherapy followed by definitive chemoradiotherapy and consolidation immunotherapy for unresectable stage III non-small cell lung cancer: a multi-in... حسب Zhixue Fu (7540256)

"…The I-CRT-I group showed a significant improvement in OS compared with the CRT-I group (p=0.004). …"

Table 1_Genetic diversity and antibiotic resistance of Mycobacterium bovis in bovines in the Delta area of Egypt.docx حسب Mohamed Sabry A. Elsayed (22235200)

"…Introduction<p>Mycobacterium bovis (M. bovis) causes significant financial harm to the cattle industry through decreased productivity and trade limitations, while also posing a risk to human health through zoonotic transmission, which is primarily from unpasteurized milk or close animal contact.…"

Data Sheet 1_A comparative study on tobacco prevalence and secondhand smoke exposure before and after the lockdown in Rizhao, China: analysis of 2022 and 2024 data.pdf حسب Zhao-Hui Liang (21604178)

"…The chi-square test was used to determine whether there were significant differences.</p>Result<p>A total of 1872 valid questionnaires were collected from the two surveys. …"

Supplementary file 1_IGF-1 secreted by mesenchymal stem cells affects the function of lymphatic endothelial progenitor cells: a potential strategy for the treatment of lymphedema.d... حسب Zekuan Xue (21398444)

"…<p>Mesenchymal stem cells (MSCs) can participate in lymphangiogenesis through paracrine effects, while lymphatic endothelial progenitor cells (LEPCs), a subpopulation of endothelial progenitor cells (EPCs), can differentiate into mature lymphatic endothelial cells, thereby influencing lymphatic function. …"

Major hyperparameters of RF-SVR. حسب Jintao Li (448681)

"…For instance, the RF-MLPR model achieved a 3.7%–6.5% improvement in the Nash-Sutcliffe efficiency (NSE) metric across four hydrological stations compared to the RF-SVR model. (4) Prediction accuracy decreased with longer forecast periods, with the R² value dropping from 0.8886 for a 1-month forecast to 0.6358 for a 12-month forecast, indicating the increasing challenge of long-term predictions due to greater uncertainty and the accumulation of influencing factors over time. (5) The RF-MLPR model outperformed the RF-SVR model, demonstrating a superior ability to capture the complex, nonlinear relationships inherent in the data. …"

Pseudo code for coupling model execution process. حسب Jintao Li (448681)

"…For instance, the RF-MLPR model achieved a 3.7%–6.5% improvement in the Nash-Sutcliffe efficiency (NSE) metric across four hydrological stations compared to the RF-SVR model. (4) Prediction accuracy decreased with longer forecast periods, with the R² value dropping from 0.8886 for a 1-month forecast to 0.6358 for a 12-month forecast, indicating the increasing challenge of long-term predictions due to greater uncertainty and the accumulation of influencing factors over time. (5) The RF-MLPR model outperformed the RF-SVR model, demonstrating a superior ability to capture the complex, nonlinear relationships inherent in the data. …"

Major hyperparameters of RF-MLPR. حسب Jintao Li (448681)

"…For instance, the RF-MLPR model achieved a 3.7%–6.5% improvement in the Nash-Sutcliffe efficiency (NSE) metric across four hydrological stations compared to the RF-SVR model. (4) Prediction accuracy decreased with longer forecast periods, with the R² value dropping from 0.8886 for a 1-month forecast to 0.6358 for a 12-month forecast, indicating the increasing challenge of long-term predictions due to greater uncertainty and the accumulation of influencing factors over time. (5) The RF-MLPR model outperformed the RF-SVR model, demonstrating a superior ability to capture the complex, nonlinear relationships inherent in the data. …"

Results of RF algorithm screening factors. حسب Jintao Li (448681)

"…For instance, the RF-MLPR model achieved a 3.7%–6.5% improvement in the Nash-Sutcliffe efficiency (NSE) metric across four hydrological stations compared to the RF-SVR model. (4) Prediction accuracy decreased with longer forecast periods, with the R² value dropping from 0.8886 for a 1-month forecast to 0.6358 for a 12-month forecast, indicating the increasing challenge of long-term predictions due to greater uncertainty and the accumulation of influencing factors over time. (5) The RF-MLPR model outperformed the RF-SVR model, demonstrating a superior ability to capture the complex, nonlinear relationships inherent in the data. …"

Schematic diagram of the basic principles of SVR. حسب Jintao Li (448681)

"…For instance, the RF-MLPR model achieved a 3.7%–6.5% improvement in the Nash-Sutcliffe efficiency (NSE) metric across four hydrological stations compared to the RF-SVR model. (4) Prediction accuracy decreased with longer forecast periods, with the R² value dropping from 0.8886 for a 1-month forecast to 0.6358 for a 12-month forecast, indicating the increasing challenge of long-term predictions due to greater uncertainty and the accumulation of influencing factors over time. (5) The RF-MLPR model outperformed the RF-SVR model, demonstrating a superior ability to capture the complex, nonlinear relationships inherent in the data. …"

Image_2_Trends and predictions of maternal sepsis and other maternal infections among women of childbearing age: a systematic analysis for the global burden of disease study 2019.T... حسب Hang Qian (444740)

"…From 2020 to 2044, the global age-standardized incidence rate of MSMIs in WCBA was predicted to decrease whereas the case number increases slowly.</p>Conclusion<p>The global trends in MSMIs incidence and mortality generally showed a decline with considerable heterogeneity, indicating both the effectiveness and unevenness of global management of MSMIs. …"

Data Sheet 1_Global, regional, and national burden of pneumococcal disease among children and adolescents aged <20 years from 1990 to 2021: a predictive analysis.docx حسب Gan-min Wang (21188933)

"…Despite a global decrease in burden, significant regional and socioeconomic disparities, as well as long-term trends, are not fully understood.…"

Table_1_Trends and predictions of maternal sepsis and other maternal infections among women of childbearing age: a systematic analysis for the global burden of disease study 2019.X... حسب Hang Qian (444740)

"…From 2020 to 2044, the global age-standardized incidence rate of MSMIs in WCBA was predicted to decrease whereas the case number increases slowly.</p>Conclusion<p>The global trends in MSMIs incidence and mortality generally showed a decline with considerable heterogeneity, indicating both the effectiveness and unevenness of global management of MSMIs. …"