Data Sheet 1_Therapeutic effects of traditional Chinese medicine Hua-Feng-Dan in a rat model of ischemic stroke involve renormalization of gut microbiota.docx حسب Xiaoxia He (459582)

"…<p>Hua-Feng-Dan is a traditional Chinese medicine used to treat ischemic stroke, but little is known about its therapeutic mechanism. …"

Data Sheet 1_Efficacy and safety of shensong yangxin capsules for persistent atrial fibrillation: a Systematic Review and meta-analysis of randomized controlled trials.docx حسب Yifan Chen (446592)

"…SSYX combined with conventional treatments (CTs) significantly lowered the recurrence of AF compared to CTs alone (risk ratio [RR] = 0.65, 95% conffdence interval [CI] 0.56 to 0.75, P < 0.001). …"

Data Sheet 1_Microbiota profiling from biopsied tissues in complex infections: a diagnostic and prognostic analysis through metagenomic next-generation sequencing.docx حسب Tiange Song (13878401)

"…Early mNGS sampling within 7 days after admission was associated with a significantly decreased risk of all-cause mortality (HR 0.18, 95% CI 0.04–0.94; P=0.04), treatment failure (OR 0.17, 95% CI 0.05–0.66; P=0.01), and increased probability of clinical resolution (OR 3.03, 95% CI 1.24–7.40; P=0.01).…"

Experimental protocol and behavioral evidence of perceptual learning. حسب Sarit F.A. Szpiro (21094755)

"…Note that these estimate plots depict the group-level estimate distributions for illustration purposes; however, the analysis was based on a mixed-effects linear model that accounts for individual variability across groups and participants, thereby addressing the often bi-modal estimate distributions observed in individual participants (Fig A in <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1012980#pcbi.1012980.s001" target="_blank">S1 Text</a>, <a href="http://www.ploscompbiol.org/article/info:doi/10.1371/journal.pcbi.1012980#pcbi.1012980.g002" target="_blank">Fig 2</a>). …"

Box plot of queens and males in the young colony (left) and old colony (right) A-B compares the queens and males distribution in the young and old colonies, respectively. حسب Moïse Pierre Exélis (21578515)

Data Sheet 1_Protein-free domains in native and ferroptosis-driven oxidized cell membranes: a molecular dynamics study of biophysical properties and doxorubicin uptake.pdf حسب Yaser Shabanpour (13247160)

"…Importantly, we found that DOX could penetrate the oxidized ferroptosis membrane with a lower free-energy barrier (∆G_PB) of approximately 38 kJ.mol⁻¹. …"

Changes in intraocular pressure (IOP) from before to after omidenepag isopropyl administration in different patient groups. حسب Kana Tokumo (21702784)

"…<b>(b)</b> Comparison of IOP before and after omidenepag isopropyl in the new administration group. There was a significant decrease in IOP after starting the eye drops (<i>P</i> = 0.03, Wilcoxon signed-rank test).…"

Data Sheet 1_Short-term structured dietary and exercise interventions delay diabetes onset in prediabetic patients: a prospective quasi-experimental study.pdf حسب Zhen Wang (72451)

"…The prevalence of abnormal blood glucose markers—FBG, 2h OGTT, and HbA1C—significantly decreased within each intervention group after short-term intervention and 6 months of follow-up. …"

Data Sheet 1_Pharmacist-led surgical medicines prescription optimization and prediction service improves patient outcomes - a machine learning based study.docx حسب Xianlin Li (2004964)

"…In Phase 3, the acceptance rate of pharmacist recommendations rose to 71.3%, while the length of stay, total hospitalization costs, and medication costs significantly decreased (p < 0.05), indicating overall improvement compared to Phase 1.…"

Data Sheet 1_Prevalence trends, population characteristics and treatment outcomes of tuberculosis combined with diabetes in Southwest China: a register-based retrospective study.do... حسب Deliang Kong (382201)

"…</p>Results<p>From 2016 to 2022, the incidence rate of PTB in southwest China showed a decreasing trend (AAPC = -10.22, 95% CI: −11.49% ~ −8.94%), while the incidence rate of PTB-DM increased rapidly (AAPC = 14.25, 95% CI: 11.35% ~17.23%). …"

Spaceflight in microgravity reduces sGAG content in the femoral head and distal epiphysis. حسب Rukmani Cahill (20939813)

Table 1_Thymoquinone/β-N-acetylglucosaminidase, a novel plant-derived combination, inhibited quorum sensing signaling pathways and disrupted biofilm in Staphylococcus aureus.docx حسب Adel Attia M. Ahmad (16729177)

"…Notably, NAGase, whether used alone or in conjunction with TQ, led to a decrease in the expression of the atl, icaA, and agr genes.…"

<b>A note on the effects of classical music as environmental enrichment for white-lipped peccaries (</b><b><i>Tayassu pecari</i></b><b>)</b> حسب Sergio Nogueira-Filho (10808859)

"…Our results indicate that classical music significantly increased exploratory behaviors (P<0.05) and decreased inactivity (P<0.05) in peccaries, suggesting a positive welfare effect. …"

Data Sheet 1_Finite-element analysis-based design and efficacy assessment of a three-dimensional anisotropic heel cushioning pad for diabetic foot management.xlsx حسب Xiong-Gang Yang (22645370)

"…Background<p>Diabetic foot ulcer (DFU) is a common complication observed in diabetic patients, which can lead to lower limb amputation in severe cases and seriously impair the patient’s mobility and even endanger life. …"

Data Sheet 1_Association between the systemic immune-inflammatory index and the immune response after hepatitis B vaccination: a cross-sectional analysis of NHANES data.docx حسب Jiayan Hu (18593615)

"…Notably, antibody expression significantly decreased as the SII increased beyond the threshold of 448.3.…"

Data Sheet 2_The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review.pdf حسب Thiago Henrique Teodoro (20703731)

"…</p>Conclusion<p>Chronic exercise decreases serum TNF-α and IL-6 levels, lowers the CD4/CD8 ratio, and increases IL-10 after 24 weeks, aiding Th1 and Th2 balance. …"

Data Sheet 1_The effects of acute and chronic exercise on immune markers of TH1/TH2 cells in older adults: a systematic review.pdf حسب Thiago Henrique Teodoro (20703731)

"…</p>Conclusion<p>Chronic exercise decreases serum TNF-α and IL-6 levels, lowers the CD4/CD8 ratio, and increases IL-10 after 24 weeks, aiding Th1 and Th2 balance. …"

Data Sheet 1_Standardized Rhodiola rosea injection for left ventricular remodeling and inflammation in patients with HFrEF: a systematic review and meta-analysis.docx حسب Xuqin Du (8803772)

"…Sensitivity analyses confirmed the robustness of these findings, and no significant publication bias was detected.</p>Conclusion<p>SRRI appears to effectively enhance LVR, reduce inflammatory mediators, and improve clinical effectiveness in HFrEF patients while maintaining a favorable safety profile. …"

Image 1_Comparison between the protective effect of the orally administered atorvastatin and safflower (Carthamus tinctorius) in hypercholesterolemic male rats.pdf حسب Haddad A. El Rabey (22248019)

"…The induced hypercholesterolemia significantly raised liver function enzymes, lipid peroxidation (14.9 ± 0.11 mg/dL), total cholesterol (273.3 ± 1.1 mg/dL), triglycerides (223.0 ± 4.1 mg/dL), low-density lipoproteins (204.7 ± 0.9 mg/dL), very low-density lipoproteins (44.6 ± 0.8 mg/dL), troponin, creatine kinase (CK), and adrenaline while decreased antioxidant enzymes, high-density lipoprotein (HDL), and vitamin D (11.1 ± 0.5 ng/mL). …"

Table 1_Comparison between the protective effect of the orally administered atorvastatin and safflower (Carthamus tinctorius) in hypercholesterolemic male rats.docx حسب Haddad A. El Rabey (22248019)

"…The induced hypercholesterolemia significantly raised liver function enzymes, lipid peroxidation (14.9 ± 0.11 mg/dL), total cholesterol (273.3 ± 1.1 mg/dL), triglycerides (223.0 ± 4.1 mg/dL), low-density lipoproteins (204.7 ± 0.9 mg/dL), very low-density lipoproteins (44.6 ± 0.8 mg/dL), troponin, creatine kinase (CK), and adrenaline while decreased antioxidant enzymes, high-density lipoprotein (HDL), and vitamin D (11.1 ± 0.5 ng/mL). …"