Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout حسب Alper James Alcaraz (20977320)

"…Benchmark concentration analysis of transcriptomic responses at 4 dph, based on the most sensitive transcriptomic features, yielded tPODs between 0.028 and 0.47 μg/L B[<i>a</i>]P. At 28 dph, Cyp1a1 exhibited significantly increased catalytic activity, with biochemical POD, bPOD_EROD,28dph of 0.599 μg/L B[<i>a</i>]P, while morphometric analysis showed significant growth inhibition in terms of length, with apical POD, aPOD_length,28dph of 1.77 μg/L B[<i>a</i>]P, with a notable decreasing trend in body weight. …"

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout حسب Alper James Alcaraz (20977320)

"…Benchmark concentration analysis of transcriptomic responses at 4 dph, based on the most sensitive transcriptomic features, yielded tPODs between 0.028 and 0.47 μg/L B[<i>a</i>]P. At 28 dph, Cyp1a1 exhibited significantly increased catalytic activity, with biochemical POD, bPOD_EROD,28dph of 0.599 μg/L B[<i>a</i>]P, while morphometric analysis showed significant growth inhibition in terms of length, with apical POD, aPOD_length,28dph of 1.77 μg/L B[<i>a</i>]P, with a notable decreasing trend in body weight. …"

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout حسب Alper James Alcaraz (20977320)

"…Benchmark concentration analysis of transcriptomic responses at 4 dph, based on the most sensitive transcriptomic features, yielded tPODs between 0.028 and 0.47 μg/L B[<i>a</i>]P. At 28 dph, Cyp1a1 exhibited significantly increased catalytic activity, with biochemical POD, bPOD_EROD,28dph of 0.599 μg/L B[<i>a</i>]P, while morphometric analysis showed significant growth inhibition in terms of length, with apical POD, aPOD_length,28dph of 1.77 μg/L B[<i>a</i>]P, with a notable decreasing trend in body weight. …"

Transcriptomics Points-of-Departure (tPODs) to Support Hazard Assessment of Benzo[<i>a</i>]pyrene in Early-Life-Stage Rainbow Trout حسب Alper James Alcaraz (20977320)

"…Benchmark concentration analysis of transcriptomic responses at 4 dph, based on the most sensitive transcriptomic features, yielded tPODs between 0.028 and 0.47 μg/L B[<i>a</i>]P. At 28 dph, Cyp1a1 exhibited significantly increased catalytic activity, with biochemical POD, bPOD_EROD,28dph of 0.599 μg/L B[<i>a</i>]P, while morphometric analysis showed significant growth inhibition in terms of length, with apical POD, aPOD_length,28dph of 1.77 μg/L B[<i>a</i>]P, with a notable decreasing trend in body weight. …"

Transcript response differences between T1R and LEP patients for GO terms, KEGG or Reactome pathways that showed significant enrichment for both the LEP and T1R groups. حسب Wilian Correa-Macedo (11813183)

"…<b>(A)</b> Dotplots of group mean Log₂FC of all DET of a given term. …"

PAM16 correlation with N-MYC. حسب Zahra Motahari (6814013)

Expression of MAGMAS in medulloblastoma. حسب Zahra Motahari (6814013)

Trends over 10 years (2011–2021) in clinical characteristics of children with severe acute malnutrition admitted at Moyo NRU. حسب Mphatso Nancy Chisala (20477275)

Trends over 10 years in children with severe acute malnutrition admitted at Moyo NRU. حسب Mphatso Nancy Chisala (20477275)

MAGMAS inhibition on mitochondrial activity in medulloblastoma cells. حسب Zahra Motahari (6814013)

MAGMAS inhibition induces medulloblastoma cell death. حسب Zahra Motahari (6814013)

BT9 reduces DAOY and D425 medulloblastoma cell invasion. حسب Zahra Motahari (6814013)

"…(C) Compared to control, BT9 treatment significantly decreased the number of invading DAOY and D425 cells (****p < 0.0001, BT9 vs vehicle control, n = 6). 4x magnification.…"

The effect of MAGMAS inhibition on mitochondrial respiration and acidification rate in D425 cells. حسب Zahra Motahari (6814013)

MAGMAS inhibition reduces DAOY cells migration. حسب Zahra Motahari (6814013)

BT9 did not improve survival in the orthotopic xenograft model of D425 medulloblastoma. حسب Zahra Motahari (6814013)

Brain transition cost correlates with task demand and performance. حسب Giacomo Barzon (19832364)

Schematic presentation <i>M</i>. <i>bovis</i> PG45 5′ nucleotidase and phylogenetic tree of its homologs. حسب Aga E. Gelgie (17661720)

Oligonucleotides used in this study. حسب Aga E. Gelgie (17661720)

"…In comparison to the parent strain, the 0690::Tn mutant displayed markedly reduced fitness, as evidenced by a significant decrease or even absence in post-challenge mycoplasma counts in murine and cow mammary tissues, respectively. …"

Data supporting the findings of this study. حسب Aga E. Gelgie (17661720)

"…In comparison to the parent strain, the 0690::Tn mutant displayed markedly reduced fitness, as evidenced by a significant decrease or even absence in post-challenge mycoplasma counts in murine and cow mammary tissues, respectively. …"

<i>M</i>. <i>bovis</i> 0690::Tn mutant failed to elicit the recruitment of neutrophils into milk spaces. حسب Aga E. Gelgie (17661720)