Table 2_A zebrafish model of crim1 loss of function has small and misshapen lenses with dysregulated clic4 and fgf1b expression.docx by Tien Le (634791)

“…We used Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9 to make a stable Danio rerio model of crim1 deficiency, generating zebrafish that were homozygous for a 2 basepair deletion, c.339_340delCT p.Leu112Leufs*, in crim1.…”

DataSheet1_Asparagus officinalis L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.pdf by Ziwei Fang (10115899)

“…Asparagus officinalis extract treatment for 4 weeks resulted in a significant reduction in tumor growth in Lkb1^fl/flp53^fl/fl mice under both obese and lean conditions, with a decrease in Ki-67 and vascular endothelial growth factor expression and an increase in Bip expression in endometrial tumors.…”

DataSheet2_Asparagus officinalis L. extract exhibits anti-proliferative and anti-invasive effects in endometrial cancer cells and a transgenic mouse model of endometrial cancer.pdf by Ziwei Fang (10115899)

“…Asparagus officinalis extract treatment for 4 weeks resulted in a significant reduction in tumor growth in Lkb1^fl/flp53^fl/fl mice under both obese and lean conditions, with a decrease in Ki-67 and vascular endothelial growth factor expression and an increase in Bip expression in endometrial tumors.…”

Data Sheet 1_Diverging trends in the global burden of ischemic heart disease attributable to non-optimal temperatures: a historical analysis (1990–2021) and 2050 projections.csv by Zehao Jin (11408687)

“…Significant socioeconomic disparities were observed, with low-to-middle SDI regions bearing a disproportionate share (75.0%) of the global high non-optimal temperature-related mortality burden. …”

Table 1_Depression score and body mass index mediate the association between dietary vitamin C intake and female infertility: a study based on NHANES 2013–2018.xlsx by Lingxin Zheng (14554387)

“…A threshold non-linear association between VC and infertility was more significant in women aged from 18 to 34 (P = 0.033). …”

Image 1_Depression score and body mass index mediate the association between dietary vitamin C intake and female infertility: a study based on NHANES 2013–2018.tif by Lingxin Zheng (14554387)

“…A threshold non-linear association between VC and infertility was more significant in women aged from 18 to 34 (P = 0.033). …”

Data Sheet 1_Association of estimated glucose disposal rate with atrial fibrillation, heart failure and cardiovascular mortality in patients with diabetes: a prospective cohort stu... by Zhen Tan (384977)

“…The cumulative incidence of AF, HF, and cardiovascular mortality in the higher quartiles of GDR were significantly lower than those in the lowest quartile (log-rank P < 0.001 for all). eGDR exhibited an independent negative linear correlation with the risk of AF (HR = 0.94, 95% CI: 0.91-0.96), HF (HR = 0.78, 95% CI: 0.74-0.82), and cardiovascular mortality (HR = 0.86, 95% CI: 0.83-0.88) risk. eGDR made the most significant contribution to the predicted outcomes. …”

Table 1_From feed to field: effect of dietary protein level and use of a blend of feed additives on gaseous emissions from growing-finishing pig slurry.docx by Esperanza Fuertes (20628794)

“…The low-protein diet supplemented with additives (LPA) significantly reduced slurry pH (P ≤ 0.001) and urinary NH₃-N excretion (interaction, P = 0.03), improving nutrient digestibility and lowering organic matter content in slurry (P < 0.05). …”

Data Sheet 1_A peptide mimic of SOCS1 modulates equine peripheral immune cells in vitro and ocular effector functions in vivo: implications for recurrent uveitis.pdf by Lauren Stewart Stafford (17937497)

“…</p>Results<p>Following SOCS1-KIR pretreatment, cell proliferation significantly decreased in control, but not ERU-derived PBMCs. …”

Table 1_Remimazolam used for sedation during spinal anesthesia puncture provides faster sedation effect and increase recovery rate compared to midazolam: a randomized controlled tr... by Peipei Sun (416208)

“…Both groups showed significant within-group decreases in mean arterial pressure during sedation (remimazolam: from 81.5 to 75 mmHg; midazolam: from 81.7 to 72.4 mmHg; P < 0.05), with no significant inter-group difference. …”

Data Sheet 1_Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner.docx by Moriah R. Arnold (20908868)

“…Furthermore, decreased tumor volume is correlated with a decreased DNA damage signature and increased apoptotic markers, indicating a role for αSyn in modulating the DNA damage response (DDR) pathway. …”

Image 3_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…This study evaluated the therapeutic potential of immune-evasive human induced pluripotent stem cell-derived neural stem cells (3KO-NSCs) in a mouse model of ASD.</p>Methods<p>We used a valproic acid (VPA)-induced ASD model in C57BL/6 mice. …”

Image 1_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…This study evaluated the therapeutic potential of immune-evasive human induced pluripotent stem cell-derived neural stem cells (3KO-NSCs) in a mouse model of ASD.</p>Methods<p>We used a valproic acid (VPA)-induced ASD model in C57BL/6 mice. …”

Image 5_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…This study evaluated the therapeutic potential of immune-evasive human induced pluripotent stem cell-derived neural stem cells (3KO-NSCs) in a mouse model of ASD.</p>Methods<p>We used a valproic acid (VPA)-induced ASD model in C57BL/6 mice. …”

Image 4_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…This study evaluated the therapeutic potential of immune-evasive human induced pluripotent stem cell-derived neural stem cells (3KO-NSCs) in a mouse model of ASD.</p>Methods<p>We used a valproic acid (VPA)-induced ASD model in C57BL/6 mice. …”

Image 6_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…This study evaluated the therapeutic potential of immune-evasive human induced pluripotent stem cell-derived neural stem cells (3KO-NSCs) in a mouse model of ASD.</p>Methods<p>We used a valproic acid (VPA)-induced ASD model in C57BL/6 mice. …”

Image 2_3KO-NSCs ameliorate behavioral deficits and modulate gut microbiota in a VPA-induced C57BL/6 mouse model of autism.tif by Caixia Wu (8959697)

“…This study evaluated the therapeutic potential of immune-evasive human induced pluripotent stem cell-derived neural stem cells (3KO-NSCs) in a mouse model of ASD.</p>Methods<p>We used a valproic acid (VPA)-induced ASD model in C57BL/6 mice. …”

Image 1_Long-term adoption of plow tillage and green manure improves soil physicochemical properties and optimizes microbial communities under a continuous peanut monoculture syste... by Yunfeng Yao (7136525)

“…It was found that both PTGM and PT remarkably decreased the average bulk density (BD), while elevated the mean soil porosity (SP) in 0–30 cm soil layer. …”

Table 1_Comparison of preoperative education by artificial intelligence versus traditional physicians in perioperative management of urolithiasis surgery: a prospective single-blin... by Hui Zhang (7197)

“…At 3 h pre-op, physician and ChatGPT groups maintained lower anxiety, while Ernie Bot showed a non-significant rebound. …”

Table 1_Longitudinal relationships between daily activities, depressive symptoms, anxiety, and suicidality during the COVID-19 pandemic: a three-wave cross-lagged study.docx by Juhee Choi (2619733)

“…Autoregressive and cross-lagged effects were investigated using a cross-lagged panel analysis.</p>Results<p>Reduced daily activities contributed to increased depression, anxiety, and suicidality, which, in turn, resulted in further decreases in daily activities in subsequent waves. …”