Ameliorative impact of Juniperus Macrocarpa extract on methotrexate-induced hepatic damage in rats by Shahad Hassan Hadi (20141025)

“…Rats in groups 3 and 4 were given daily dosages of 100 mg and 200 mg of Juniperus macrocarpa aqueous extract, respectively, for two weeks before receiving a single intraperitoneal MTX injection. Juniperus macrocarpa extracts at both low and high doses substantially alleviated the MTX-provoked biochemical alterations, as evidenced by decreased levels of inflammatory parameters including TNF-α and IL-6 and hepatic enzymes including ALT, AST, and ALP. …”

Data Sheet 1_Cordycepin attenuates NLRP3/Caspase-1/GSDMD-mediated LPS-induced macrophage pyroptosis.pdf by Zige Liu (20724752)

“…Cordycepin pre-treatment significantly reduced ROS levels and XO activity, inhibited the expression of NLRP3, cleaved-Caspase-1, and cleaved-GSDMD, and decreased pyroptosis-associated inflammatory cytokines IL-1β and IL-18, along with Caspase-1 activity. …”

Oral L-Arginine Treatment Attenuates <i>Cryptococcus neoformans</i> Extrapulmonary Dissemination and Disease Progression by Adithap Hansakon (21708473)

“…We found significant depletion of serum L-arginine and its downstream metabolites, accompanied by increased arginase activity in infected tissues, indicating a disrupted metabolic balance. …”

3-D burrow morphology of <i>Chondrites targionii</i> (Brongniart, 1828) from an Upper Jurassic firmground of Southern Germany by Franz-Josef Scharfenberg (13134765)

“…With intermediate effect size, statistically compared branch widths revealed significantly decreasing widths from unbranched tunnels over root branches to their side branches, which, along with the scale-leaf-shaped structures, may indicate a vermiform tracemaker. …”

Data Sheet 1_Mechanism of salidroside promoting testosterone secretion induced by H2O2 in TM3 Leydig cells based on metabolomics and network pharmacology.zip by Zixu Wang (6297470)

“…<p>Oxidative stress-induced damage is a significant contributor to the impairment of Leydig cells in the testes, potentially diminishing the secretion of testosterone and other androgens, thereby resulting in testosterone deficiency. …”

Table 1_Analysis and validation of biomarkers and immune cell infiltration profiles in unstable coronary atherosclerotic plaques using bioinformatics and machine learning.xlsx by Pengyue Jin (11657894)

“…Introduction<p>Decreased stability of coronary atherosclerotic plaques correlates with a heightened risk of acute coronary syndrome (ACS). …”

Vitreous Olink Proteomics Uncovers Novel Inflammatory Proteins in Patients with Proliferative Diabetic Retinopathy by Jiayu Zhang (128702)

“…Key findings revealed 22 differentially expressed proteins (DEPs) when comparing the PDR and IMH groups, with 21 proteins showing increased expression and only one demonstrating decreased levels. Among these DEPs, fibroblast growth factor 23 (FGF23) emerged as a particularly promising candidate, as elevated expression was observed in retinal tissue from both diabetic (db/db) mice and the high-glucose (HG) or glyoxal-treated Müller glia (MG) cultures. …”

Data Sheet 1_BMP9 induces postnatal zonal stratification of immature articular cartilage through reconfiguration of the existing collagen framework.pdf by Miles Anderson-Watters (20626604)

“…In explants exposed to BMP9, collagen fibrils underwent angular displacement from 19° to 78° with respect to the surface, cell density decreased 1.77-fold, and chondrons were significantly larger. …”

Other differentially-accumulated metabolites in <i>P</i>. <i>fijiensis</i> exposed to thiabendazole. by María Gabriela Maridueña-Zavala (3377081)

“…Values represent the means and standard errors of 5 replicates. Different letters represent significant differences (p < 0.05).…”

Data Sheet 1_Acute hypobaric hypoxia attenuates the anti-fatigue effects of pitolisant by downregulating the expression of organic cation transporter 1 and P-glycoprotein.docx by Gang Zhao (161405)

“…Additionally, gene and protein expression levels of P-glycoprotein (P-gp) and organic cation transporter 1 (OCT1) were assessed to explore the mechanisms by which HH affects pitolisant’s pharmacodynamics.</p>Results<p>A 40 mg/kg dose of pitolisant significantly improved learning, memory, cognitive, and motor functions in sleep-deprived mice under HH conditions (P < 0.05). …”

Table 3_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.xlsx by Lichao Cao (276107)

“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”

Insight into Greenhouse Gas Emission Characteristics of Light-Duty Vehicles in China Driven by Technological Innovation by Xinping Yang (17371783)

“…As anticipated, with advancements in emission standards and powertrains, vehicular GHG emissions have significantly decreased. However, our findings also revealed surprising trends. …”

Table 2_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.xlsx by Lichao Cao (276107)

“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”

Image 2_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif by Lichao Cao (276107)

“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”

Table 1_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.docx by Lichao Cao (276107)

“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”

Image 3_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif by Lichao Cao (276107)

“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”

Fig 3 - by Laura Garcia-Toscano (20477540)

“…<p>Hsp90 mutation or inhibition decreases accumulation of phosphorylated TDP-43 <b>A.…”

Image 1_Endoplasmic reticulum stress-related prognosis signature characterizes the immune landscape and predicts the prognosis of colon adenocarcinoma.tif by Lichao Cao (276107)

“…Compared with normal tissues, the mRNA and protein expressions of three ERSGs were decreased in cancer tissues. Compared with NCM460, the mRNA levels of HSPA1A and DAPK1 were decreased in the majority of COAD cell lines, whereas the mRNA level of SERPINA1 was increased in HCT116 and SW480, and reduced in SW620. …”

The effect of Tawny crazy ants on the abundance of aboveground insect abundance in Texas by Ryan Reihart (9174179)

“…We also found that in areas where <i>N. fulva </i>were abundant, there was a significantly greater abundance of honeydew-producing hemiptera from the Cicadellidae family, which is a likely factor aiding in the dominance and further spread of <i>N. fulva</i>. …”

Table 1_Intravitreal aflibercept for diabetic macular edema: structural and functional improvements.docx by Chuanhe Zhang (17601519)

“…After treatment, CRT decreased, BVCA, MLS, and fixation stability improved (all p < 0.001). …”