Image 3_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…Two weeks later, mice were immunized intranasally with a single dose of 10⁴ pfu of TK- HSV-2 and 4- or 6-weeks later, blood sera and vaginal washes were collected to measure IgG total and subtypes by ELISA. …”

Image 4_Estradiol enhances B cell humoral immune responses against genital herpes simplex virus type 2 in mice through an IL-17 dependant pathway.tiff by M. Firoz Mian (10013314)

“…Two weeks later, mice were immunized intranasally with a single dose of 10⁴ pfu of TK- HSV-2 and 4- or 6-weeks later, blood sera and vaginal washes were collected to measure IgG total and subtypes by ELISA. …”

Data Sheet 1_Improved myocardial mitochondrial energy metabolism in rats with chronic heart failure by modifying fatty acid oxidation using an extract of sand-fired aconite (Jianch... by Hongtao Zhang (167639)

“…This study investigated myocardial mitochondrial energy metabolism as a therapeutic mechanism of SFAS in doxorubicin-induced chronic heart failure (CHF) rats.…”

DataSheet1_Effects of fertilization on litter decomposition dynamics and nutrient release in orchard systems.docx by Huayue Nie (20385747)

“…<p>Plant litter decomposition is a significant ecosystem function that regulates nutrient cycling, soil fertility, and biomass production. …”

Data Sheet 2_Predicting mortality in heart failure: BUN/creatinine ratio in MIMIC-III.docx by Changsen Zhu (20821991)

“…Nonlinear regression revealed a U-shaped relationship between BCR and mortality: at BCR levels below 12.5, there was no significant correlation with long-term mortality; between 12.5 and 22, BCR appeared to exert a protective effect; and above 22, it emerged as a significant risk factor.…”

Data Sheet 1_Predicting mortality in heart failure: BUN/creatinine ratio in MIMIC-III.csv by Changsen Zhu (20821991)

“…Nonlinear regression revealed a U-shaped relationship between BCR and mortality: at BCR levels below 12.5, there was no significant correlation with long-term mortality; between 12.5 and 22, BCR appeared to exert a protective effect; and above 22, it emerged as a significant risk factor.…”

Data Sheet 1_Elucidating the mechanism of stigmasterol in acute pancreatitis treatment: insights from network pharmacology and in vitro/in vivo experiments.pdf by Xuanlin Zhao (20466980)

“…Stigmasterol, a natural plant sterol found in various herbs and vegetables, exhibits a significant anti-inflammatory, antioxidant, and cholesterol-lowering effects. …”

Data Sheet 1_Active layer and permafrost microbial community coalescence increases soil activity and diversity in mixed communities compared to permafrost alone.docx by Stacey J. Doherty (6629561)

“…Respiration rates were highest in the 100% active layer soils, averaging 19.8 μg C-CO₂ g^–1 dry soil d^–1 across both sites, and decreased linearly as the ratio of permafrost increased. …”

C2CD3 regulates spatial organization of centriole architecture. by Eloïse Bertiaux (5309927)

“…<p><b>(A, B)</b> Expanded U2OS centrioles treated with siCTRL or siC2CD3, stained for α/β-tubulin (magenta) and Hs-SAS6 (green); P = procentrioles, * = C2CD3-depleted. …”

Table 1_Improved medical protective clothing comfort for medical staff facing high-intensity infectious diseases.docx by Cheng-teng Jiang (22028945)

“…</p>Results<p>Comparative assessments revealed that the new MPC enhanced air permeability to 120 mm/s, reduced sweating by 30%, decreased skin temperature by 1.2°C, and lowered the incidence of skin maceration by 45%. …”

Data Sheet 1_Interstitial fluid transport in linea alba is involved in acupuncture-induced attenuation of ovarian hypofunction in aged rats.pdf by Yaoyao Zhu (3487937)

“…Background<p>Age-related ovarian dysfunction, characterized by declining follicular reserve and hormonal imbalance, poses a significant challenge in reproductive endocrinology, severely compromising fertility and quality of life. …”

Preeclamptic plasma disrupts endothelial function and promotes inflammation in endothelial cells: beneficial effects of glibenclamide and MCC950 in this scenario by Karoliny Nune Santos (21752603)

“…<p>Preeclampsia (PE) is characterized by systemic endothelial dysfunction and remains a significant clinical challenge. Activation of NLRP3 inflammasome, reactive oxygen species (ROS) production, and pyroptosis and autophagy are important mechanisms in this condition. …”

DataSheet1_Strict biennial lifecycle and anthropogenic interventions affect temporal genetic differentiation in the endangered endemic plant, Pedicularis hallaisanensis.docx by Seongjun Kim (1993465)

“…Other cluster analyses also showed that a microhabitat under historical anthropogenic interventions contained lowered genetic diversity due to a decreased genetic distance between odd-year and even-year flowering cohorts (p < 0.05). …”

<b>Canagliflozin-induced adaptive metabolism in bone</b> by Sher Bahadur Poudel (20686192)

“…Beyond this, these drugs induce various metabolic changes, including weight loss and impaired bone integrity. There is a significant gap in understanding SGLT2i-induced skeletal changes, as SGLT2 is not expressed in osteoblasts or osteocytes, which use glucose to remodel the bone matrix. …”

LRIG1 and CDK6 expression in the lateral ventricular wall cells by Hyung-song Nam (8914220)

“…Although the <i>Cdk6</i> mRNA decreases significantly in the neuroblasts, the DCX+ neuroblasts still show a lot of td-sfGFP immunoreactivity.…”

Data Sheet 1_Elevated Galectin-3 levels in the tumor microenvironment of ovarian cancer – implication of ROS mediated suppression of NK cell antitumor response via tumor-associated... by Veronika Karlsson (20457788)

“…Current cancer immunotherapies are not efficient in ovarian cancer, and there is therefore a significant need for novel treatment options. …”

Data Sheet 1_Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells.docx by Na Tian (296333)

“…Background<p>Adjuvant-induced arthritis (AIA) serves as a classic model for rheumatoid arthritis (RA), typified by inflammatory cell infiltration and joint damage. …”

Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer” by Chanping You (9067448)

“…TRIM37 overexpression decreased palbociclib sensitivity, while its knockdown enhanced sensitivity and attenuated the effect of AR on RB1 levels and drug response, establishing TRIM37 as a novel E3 ligase that bound RB1 via its MATH and C-terminal domains.…”

Table 1_The effect of self-compassion versus mindfulness interventions on autonomic responses to stress in generalized anxiety disorders.docx by Xuejun Qi (3842173)

“…We also demonstrated a significant correlation between decreased heart rate response and less negative emotions.…”

Table 1_Case Report: Application of accelerated continuous theta burst stimulation in treatment-resistant depression.docx by Guilan Sun (10587560)

“…<p>Treatment-resistant depression (TRD) poses a significant challenge in psychiatric practice. …”