Search alternatives:
greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
lower decrease » larger decrease (Expand Search), linear decrease (Expand Search), teer decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
greater decrease » greatest decrease (Expand Search), greater increase (Expand Search), greater disease (Expand Search)
lower decrease » larger decrease (Expand Search), linear decrease (Expand Search), teer decrease (Expand Search)
we decrease » _ decrease (Expand Search), a decrease (Expand Search), nn decrease (Expand Search)
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8141
Table 5_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx
Published 2025“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”
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8142
Table 1_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx
Published 2025“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”
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8143
Inclusion and exclusion table.
Published 2025“…We systematically evaluated the key findings extracted from the included articles.…”
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8144
Table 2_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx
Published 2025“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”
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8145
Table 4_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx
Published 2025“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”
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8146
Included studies.
Published 2025“…We systematically evaluated the key findings extracted from the included articles.…”
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8147
Table 3_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx
Published 2025“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”
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8148
Inclusion and exclusion criteria.
Published 2025“…We systematically evaluated the key findings extracted from the included articles.…”
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8149
Table 6_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx
Published 2025“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”
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8150
Table 1_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx
Published 2025“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”
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8151
Table 2_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx
Published 2025“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”
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8152
Table 1_Sensory reweighting for postural stability in individuals with low vision and blindness: balance adaptation and muscle co-contraction.xlsx
Published 2025“…The rectus abdominis/erector spinae ratio decreased significantly with somatosensory deprivation, whereas the gastrocnemius/tibialis anterior co-contraction index increased significantly under both visual and somatosensory deprivation, with higher co-contraction observed in both low-vision and blind participants.…”
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8153
Data Sheet 1_TSG-6 promotes healing of critical-sized bone defects in mice.pdf
Published 2025“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”
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8154
Table 3_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx
Published 2025“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”
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8155
Data Sheet 2_TSG-6 promotes healing of critical-sized bone defects in mice.pdf
Published 2025“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”
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8156
DataSheet1_Synergistic combinations of Angelica sinensis for myocardial infarction treatment: network pharmacology and quadratic optimization approach.docx
Published 2024“…Further research revealed that Z-LIG/CGA treatment significantly increased IL-1R2 levels, significantly decreased IL-17RA levels, and inhibited the activation of p-STAT1, thereby alleviating cell apoptosis after MI. …”
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8157
Legacy effects of trampling on SOC, POC, and MOC
Published 2025“…Our results showed that in 2015, soil inorganic nitrogen (SIN), fine root biomass (FRB), and microbial biomass C decreased significantly with increasing trampling intensity, whereas the negative effects weakened over the recovery period. …”
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8158
Data Sheet 1_Antimycobacterial and immunomodulatory activities of sorafenib in a preclinical mouse model of TB infection through CD4+CD25low and CD8+CD25low effector T cells.pdf
Published 2025“…In the current study, we documented a new immune modulatory characteristic of sorafenib that, upon SRB treatment, markedly increased effector T cells (Teff - CD4<sup>+</sup>CD25<sup>low</sup> and CD8<sup>+</sup>CD25<sup>low</sup>) activity and decreased regulatory T cells, the immunosuppressive T cells (Treg- CD4<sup>+</sup>CD25<sup>high</sup> and CD8<sup>+</sup>CD25<sup>high</sup>) function. …”
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8159
Data Sheet 2_Antimycobacterial and immunomodulatory activities of sorafenib in a preclinical mouse model of TB infection through CD4+CD25low and CD8+CD25low effector T cells.pdf
Published 2025“…In the current study, we documented a new immune modulatory characteristic of sorafenib that, upon SRB treatment, markedly increased effector T cells (Teff - CD4<sup>+</sup>CD25<sup>low</sup> and CD8<sup>+</sup>CD25<sup>low</sup>) activity and decreased regulatory T cells, the immunosuppressive T cells (Treg- CD4<sup>+</sup>CD25<sup>high</sup> and CD8<sup>+</sup>CD25<sup>high</sup>) function. …”
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8160
Table1_Leishmania major surface components and DKK1 signalling via LRP6 promote migration and longevity of neutrophils in the infection site.docx
Published 2024“…Relative to infected BALB/c mice, a significant reduction in parasite load was observed in both LRP6<sup>NKO</sup> and LRP6<sup>NKO</sup> DKK1<sup>PKO</sup> infected mice. …”