Supplementary file 1_Burden of ageing spectrum of diseases in China, 1990–2021: a systematic analysis of global burden of disease study 2021.pdf by Li Yang (6520)

“…Background<p>Population aging represents a pressing challenge for China, given its vast population and the growing proportion of adults aged 65 years and older. …”

Tobacco and alcohol use are the risk factors responsible for the greatest burden of head and neck cancers: a study from the Global Burden of Disease Study 2019 by Yue Yuan (113839)

“…Interestingly, the ASIRs for laryngeal cancer showed a decreasing trend over the studied time frame from 1990 to 2019. …”

Table 2_Efgartigimod for the treatment of immune checkpoint inhibitor-associated myocarditis complicated with impending crisis state of myasthenia gravis: a case report.docx by Mingjia Lu (21593324)

“…Treatment with efgartigimod (10 mg/kg) significantly improved myasthenic symptoms, with Myasthenia Gravis–Activities of Daily Living (MG-ADL) and Quantitative Myasthenia Gravis (QMG) scores decreasing from 11 to 5 and 26 to 11, respectively. …”

Image 5_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg by Yue Fu (64387)

“…In vivo efficacy was assessed using a xenograft model.</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. …”

Table 1_Decadal-scale urban footprints on seagrass blue carbon dynamics in Palk Bay, India: a remote sensing based framework.docx by Rajamohanan Pillai Ranith (22589207)

“…</p>Results<p>Results indicated a significant increase in built-up area (~12 Km2) near high-impact sites (Devipattinam, Thondi), versus ~4 Km2 increase at low-impact sites (Pamban and Mandapam North). …”

Image 8_A diaryl urea derivative, SMCl inhibits cell proliferation through the RAS/RAF/MEK/ERK pathway in hepatocellular carcinoma.jpeg by Yue Fu (64387)

“…In vivo efficacy was assessed using a xenograft model.</p>Results<p>The MTS and colony formation assays demonstrated that SMCl significantly decreased the viability of HCC cells. …”

Table 3_Efgartigimod for the treatment of immune checkpoint inhibitor-associated myocarditis complicated with impending crisis state of myasthenia gravis: a case report.docx by Mingjia Lu (21593324)

“…Treatment with efgartigimod (10 mg/kg) significantly improved myasthenic symptoms, with Myasthenia Gravis–Activities of Daily Living (MG-ADL) and Quantitative Myasthenia Gravis (QMG) scores decreasing from 11 to 5 and 26 to 11, respectively. …”

Table 1_Biochar one-off application for paddy soil 15N loss improvement: evidence from a two-year experiment.docx by Jiping Gao (3816001)

“…This study underscores the potential of biochar as a an environmentally friendly soil amendment for N loss reduction in rice systems. …”

Image 1_Biochar one-off application for paddy soil 15N loss improvement: evidence from a two-year experiment.tif by Jiping Gao (3816001)

“…This study underscores the potential of biochar as a an environmentally friendly soil amendment for N loss reduction in rice systems. …”

Supplementary Material for: Camrelizumab combined with Lenvatinib and RALOX-HAIC for unresectable hepatocellular carcinoma (Cal Era): a prospective, single-arm, phase II trial by figshare admin karger (2628495)

“…This study aimed to assess the efficacy, safety, and potential predictive biomarkers of a therapeutic approach incorporating camrelizumab, lenvatinib, and a HAIC protocol using raltitrexed plus oxaliplatin (RALOX) in patients with intermediate to advanced HCC. …”

Table 1_Baicalein from Scutellaria baicalensis mitigates oxidative stress through the IIS pathway in a C. elegans model of ulcerative colitis.docx by Wei Wang (17594)

“…Introduction<p>Ulcerative colitis (UC) is a chronic, nonspecific inflammatory bowel disease with limited therapeutic options. …”

Video 2_Cardiac contractility modulation to enhance optimized medical therapy and improve cardiac remodeling in advanced heart failure: a case report.avi by Lina Feng (509270)

“…NT-proBNP levels also decreased from 6,553 pg/ml to within the normal range.…”

Video 1_Cardiac contractility modulation to enhance optimized medical therapy and improve cardiac remodeling in advanced heart failure: a case report.avi by Lina Feng (509270)

“…NT-proBNP levels also decreased from 6,553 pg/ml to within the normal range.…”

Image 1_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff by José De Jesus Bravo-Silva (21898316)

“…Melatonin, a hormone with antioxidant and immunomodulatory properties, has previously been shown to inhibit Japanese encephalitis virus (JEV) replication through RhoA pathway modulation.…”

Image 3_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff by José De Jesus Bravo-Silva (21898316)

“…Melatonin, a hormone with antioxidant and immunomodulatory properties, has previously been shown to inhibit Japanese encephalitis virus (JEV) replication through RhoA pathway modulation.…”

Image1_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png by Huijun Zhou (60485)

“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”

Image 2_Pharmacological inhibition of the RhoA pathway by melatonin reduces viral replication and proinflammatory response against ZIKV and DENV-4 neuroinfections.tiff by José De Jesus Bravo-Silva (21898316)

“…Melatonin, a hormone with antioxidant and immunomodulatory properties, has previously been shown to inhibit Japanese encephalitis virus (JEV) replication through RhoA pathway modulation.…”

Image2_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png by Huijun Zhou (60485)

“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”

Image2_Causal effect of immune cells, metabolites, cathepsins, and vitamin therapy in diabetic retinopathy: a Mendelian randomization and cross-sectional study.png by Huijun Zhou (60485)

“…Cross-sectional data indicated that vitamins B1, B2, B6, B12, and E progressively decreased with DR severity.</p>Conclusion<p>This study is the first to identify CAT H as a key risk factor for DR, while vitamins B6 and E showed significant protective effects, particularly against PDR. …”

Video 3_Cardiac contractility modulation to enhance optimized medical therapy and improve cardiac remodeling in advanced heart failure: a case report.avi by Lina Feng (509270)

“…NT-proBNP levels also decreased from 6,553 pg/ml to within the normal range.…”