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linear decrease » linear increase (Expand Search)
lower decrease » larger decrease (Expand Search), teer decrease (Expand Search), we decrease (Expand Search)
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11521
Data Sheet 1_Global, regional, and national burdens of pancreatitis in children and adolescents aged 0–24 years from 1992 to 2021: a trend analysis based on the global burden of di...
Published 2025“…Background<p>The younger onset of pancreatitis presents a significant public health challenge. This study aims to analyze the global burden of pancreatitis in younger populations based on the Global Burden of Disease 2021.…”
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11522
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11523
Presentation 1_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammat...
Published 2025“…Molecular analysis showed reduced serum levels of inflammatory cytokines TNF-α, IL-1β, and rheumatoid factor (RF). In MH7A cells, PSPA decreased inflammatory cytokines (IL-1α, IL-6, IL-18), inhibited cell proliferation (IC50 = 1.43 μg/mL), and induced apoptosis by modulating Bcl-2, Bax, Caspase-3, and Caspase-9. …”
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11524
Table 1_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel...
Published 2025“…Molecular analysis showed reduced serum levels of inflammatory cytokines TNF-α, IL-1β, and rheumatoid factor (RF). In MH7A cells, PSPA decreased inflammatory cytokines (IL-1α, IL-6, IL-18), inhibited cell proliferation (IC50 = 1.43 μg/mL), and induced apoptosis by modulating Bcl-2, Bax, Caspase-3, and Caspase-9. …”
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11525
Table 2_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel...
Published 2025“…Molecular analysis showed reduced serum levels of inflammatory cytokines TNF-α, IL-1β, and rheumatoid factor (RF). In MH7A cells, PSPA decreased inflammatory cytokines (IL-1α, IL-6, IL-18), inhibited cell proliferation (IC50 = 1.43 μg/mL), and induced apoptosis by modulating Bcl-2, Bax, Caspase-3, and Caspase-9. …”
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11526
Table 3_Extraction of anthocyanins from purple sweet potato: evaluation of anti-inflammatory effects in a rheumatoid arthritis animal model, mechanistic studies on inflammatory cel...
Published 2025“…Molecular analysis showed reduced serum levels of inflammatory cytokines TNF-α, IL-1β, and rheumatoid factor (RF). In MH7A cells, PSPA decreased inflammatory cytokines (IL-1α, IL-6, IL-18), inhibited cell proliferation (IC50 = 1.43 μg/mL), and induced apoptosis by modulating Bcl-2, Bax, Caspase-3, and Caspase-9. …”
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11527
<b>Liraglutide treatment reverses unconventional cellular defects in induced pluripotent stem cell-derived β cells harboring a partially functional </b><b><i>WFS1</i></b><b> varian...
Published 2025“…Pancreatic β cells obtained from patient-derived induced Pluripotent Stem Cells (iPSCs) carrying this <i>WFS1 </i>variant exhibited reduced insulin processing and impaired secretory granule maturation, as evidenced by proinsulin accumulation and decreased prohormone convertase PC1/3. Moreover, they exhibited dysregulated Ca<sup>2+</sup> fluxes due to altered transcription of Ca<sup>2+</sup>-related genes, including <i>CACNA1D</i>, and significantly reduced <i>SNAP25</i> levels, leading to uncoordinated oscillations and poor glucose responsiveness. …”
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11528
Map of the Comacchio Lagoon.
Published 2025“…However, they are subject to significant stressors, both natural and anthropogenic, which can alter ecosystem services and functioning and food web structure. …”
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11529
Sampling scenarios used in our experiments.
Published 2025“…<div><p>Premature birth can be defined as birth before 37 weeks of gestation, which is a significant global health issue, being the main cause for neonatal deaths. …”
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11530
Hybridsampling triple size models performance.
Published 2025“…<div><p>Premature birth can be defined as birth before 37 weeks of gestation, which is a significant global health issue, being the main cause for neonatal deaths. …”
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11531
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11532
Table 1_Danggui Buxue Decoction attenuates 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone—induced lung cancer growth in A/J mice by suppressing HIF-1α/VEGF-mediated angiogenesis.do...
Published 2025“…Despite this, current anti-angiogenic therapies face significant clinical limitations. Danggui Buxue Decoction (DBD), a traditional Chinese herbal formula used to tonify Qi and activate blood circulation, exhibits clinical potential in delaying LC progression; however, its precise mechanistic basis remains incompletely defined. …”
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11533
Data Sheet 1_Mechanisms underlying the wound healing and tissue regeneration properties of a novel gauze dressing impregnated with traditional herbal medicine (Ya-Samarn-Phlae) in...
Published 2025“…</p>Results<p>During the 6-month storage period, the α-mangostin content measured in YaSP did not decrease; however, the curcumin level showed a significant reduction. …”
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11534
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11535
<b>Increasing ECM tree dominance enhances </b><b>soil </b><b>lignin </b><b>phenols </b><b>but suppresses microbial necromass contribution to soil organic carbon in a subtropical </...
Published 2025“…Conversely, microbial-derived C accumulation decreased with ECM%, primarily because of the lower metabolic efficiency and higher degradation rate of microbial necromass, as indicated by metabolic quotient and extracellular enzyme activities, respectively. …”
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11536
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11537
Data Sheet 1_Global, regional, and national trends in ischaemic stroke burden and risk factors among adults aged 20 + years (1990–2021): a systematic analysis of data from the Glob...
Published 2025“…Males consistently faced a greater burden of IS across all subgroups. High systolic blood pressure and high low-density lipoprotein cholesterol (LDL-C) levels consistently represented the most significant risk factors contributing to DALYs from 1990 to 2021.…”
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11538
Activation of the RSC-ACC projections causes mechanical and thermal pain sensitization.
Published 2025“…CNO in hM3Dq group, **<i>p</i> = 0.0021 < 0.01, <i>n =</i> 9 mice). ns means no significant difference. Error bars indicate SEM. …”
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11539
Table 1_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden...
Published 2025“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”
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11540
Image 1_Time trends in mortality of congenital heart disease in children aged 0–14 years: a global, regional, and national cohort analysis from 1990 to 2021 using the global burden...
Published 2025“…Introduction<p>Congenital heart disease (CHD) represents a significant global public health burden, with substantial variability in mortality rates across different regions and age groups.…”