Effects of efgartigimod treatment on humoral and cellular immune responses: analysis of T-cell-dependent antibody response in cynomolgus monkeys by Ornella Binazon (20718978)

“…Anti-KLH IgG titers were lower in efgartigimod-treated animals compared with controls only after the first boost of KLH, coinciding with decreases in total IgG titers in efgartigimod-treated animals, and returned to baseline levels by the end of the recovery phase. …”

Data Sheet 1_Revealing fitness and virulence determinants of hypervirulent Klebsiella pneumoniae during infection in Galleria mellonella using a transposon library.pdf by Lisheng Xiao (15919517)

“…<p>Klebsiella pneumoniae infections represent a significant public health concern. Despite their clinical relevance, the genetic determinants underlying bacterial fitness and virulence remain incompletely characterized. …”

Data Sheet 1_Disease burden of tuberculosis in China from 1990 to 2021 and its prediction to 2036.docx by Rong Sun (532754)

“…</p>Conclusion<p>TB burden in China has decreased significantly overall in the past years. …”

S1 File - by Zsófia Tróznai (19923854)

“…Measurements of body size, body composition (InBody 720), and bone age were performed in all players who were selected to participate in the selection program (<i>n</i> = 264) (mean±sd age: 13.1±0.6 years) and in a sample of not-selected players (<i>n</i> = 266) (mean±sd age: 13.2±0.6 years). …”

TraN directs surface exclusion specificity. by Nicolas Rivard (3875746)

“…One-way ANOVA (p = 0.016) with a Tukey-Kramer post-test was used on the log₁₀-transformed values to compare the means. Statistical significance (<a href="http://www.plosgenetics.org/article/info:doi/10.1371/journal.pgen.1011442#pgen.1011442.s010" target="_blank">S2 File</a>) is shown as a compact letter display for pairwise comparisons where means grouped under identical letters are not statistically different. …”

Flowchart of the selection program. by Zsófia Tróznai (19923854)

“…Measurements of body size, body composition (InBody 720), and bone age were performed in all players who were selected to participate in the selection program (<i>n</i> = 264) (mean±sd age: 13.1±0.6 years) and in a sample of not-selected players (<i>n</i> = 266) (mean±sd age: 13.2±0.6 years). …”

Table 1_Dynamic changes of gut microbiota between the first and second trimester for women with gestational diabetes mellitus and their correlations with BMI: a nested cohort study... by Shilin Zhong (9588065)

“…</p>Results<p>In the first trimester, GDM group exhibited lower levels of Bacteroides_H and Acetatifactor compared to ND group (p < 0.05). …”

Table 2_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Table 4_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Table 1_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Table 3_Clinical features and prognosis of NMOSD patients with positive autoimmune antibodies.docx by Yutao Liu (87989)

“…</p>Results<p>(1) Anti-CTD Abs (+): higher proportion of female patients, increased relapse frequency; decreased red blood cell (RBC) count and aspartate aminotransferase (AST) levels. (2) ATAbs (+): greater incidence of acute brainstem syndrome (ABS); reduced peripheral leukocyte, neutrophil, and lymphocyte counts; elevated serum urea levels. (3) Double (+): marked female predominance, higher incidence of ABS, decreased RBC count, hemoglobin (Hb) levels, and cerebrospinal fluid (CSF) chloride concentration; elevated serum urea. (4) AQP4-IgG association: AQP4-IgG-positive patients were more frequently female, with higher prevalence of anti-CTD Abs positivity but lower prevalence of ATAbs positivity. (5) Prognostic analysis: both double-positive and single-antibody-positive groups showed higher disability (EDSS ≥4.0/≥6.0) compared with antibody-negative patients, although no significant differences were observed between the two single-antibody subgroups. (6) Multivariate analysis identified combined antibody positivity (OR = 16.292), baseline EDSS score (OR = 3.179), and age at onset (OR = 1.052) as independent predictors of poor clinical outcomes.…”

Automated matching and visualisation of magnetic flux leakage data in shale gas pipeline based on ICP and DBSCAN algorithm by Leyao Gu (17897654)

“…Furthermore, RMSE (root mean square error) and overlap rate have been used to evaluate the model. …”

Data Sheet 1_Higher soil nitrous oxide production in landscape depressions linked to soil and hydrological legacy effects.docx by Yujia Liu (318262)

“…Cu addition significantly decreased 16S rRNA abundance, eliminated AOB amoA in upland soils, and slightly reduced the tested gene abundances in depression soils. …”

Image 1_Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study.tif by Yunlin Yang (10277429)

“…</p>Conclusion<p>Metformin use was significantly associated with decreased short-term mortality among ICU patients with ARF. …”

Image 2_Correlation between metformin use and mortality in acute respiratory failure: a retrospective ICU cohort study.tif by Yunlin Yang (10277429)

“…</p>Conclusion<p>Metformin use was significantly associated with decreased short-term mortality among ICU patients with ARF. …”

Table 1_Immediate effects of extracorporeal radial pressure wave therapy on dystonia, static plantar pressure distribution, and balance in patients with Parkinson’s disease.docx by Zhiqin Xu (524585)

“…</p>Results<p>After ERPWT, significant decreases were observed in muscle tone, stiffness, and elasticity of the achilles tendon on the more PD-affected side and the anterior aspect of the planta on both feet (p < 0.05). …”

Attention reduces decision uncertainty under high cognitive demand. by Rahul Garg (3064578)

“…(L) Fraction of glomeruli with significant changes with cued-odor. Yellow: increased, dark grey: decreased, light grey: unchanged. …”

Data Sheet 1_Sex differences in the reactivity of gastric myoelectrical activity and heart rate variability as putative psychophysiological markers in human pain research.docx by Rossitza Draganova (9154951)

“…</p>Results<p>Acute pain induced significant instability in EGG slow-wave frequency and amplitude, increased tachygastria, and decreased normogastric spectral power, without evidence of sex differences. …”

Raw data DOI 10.3389fphar.2024.1483686.zip by Changlin Wang (19822068)

“…In terms of mechanism, JJJG significantly increased the levels of FT3 and FT4 and decreased TSH level in serum (P<0.05). …”

Data Sheet 1_Vagal nerve signals are modulated by spontaneous seizures in Genetic Absence Epilepsy Rats from Strasbourg.docx by Elise Collard (20913047)

“…However, this modulation decreased with age, despite stable seizure severity. …”