Data Sheet 1_TSG-6 promotes healing of critical-sized bone defects in mice.pdf by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Table 3_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Data Sheet 2_TSG-6 promotes healing of critical-sized bone defects in mice.pdf by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Efficacy and safety of anticoagulation in asymptomatic cirrhotic patients with portal vein thrombosis: a systematic review and meta-analysis by Qingping Wu (789611)

“…Compared to no intervention, anticoagulation significantly increased the PVT recanalization rate (OR = 3.89, <i>p</i> < .001) and decreased the PVT progression rate (OR = 0.28, <i>p</i> < .001) as well as overall mortality (OR = 0.66, <i>p</i> = .008). …”

<b>Feeding Ecology of the Critically Endangered </b><b><i>Gobio insuyanus </i></b><b>(Gobionidae)</b> by Julian E. JOHNSON (20653776)

“…Feeding activity was higher in the spring habitat, particularly in summer, possibly related to its stable temperature and lower turbidity. Dietary diversity was higher in the stream, potentially reflecting its greater habitat complexity, but decreased in both habitats in autumn, suggesting a seasonal decline in prey availability. …”

DataSheet1_Synergistic combinations of Angelica sinensis for myocardial infarction treatment: network pharmacology and quadratic optimization approach.docx by Wen-Di Wang (20400446)

“…Further research revealed that Z-LIG/CGA treatment significantly increased IL-1R2 levels, significantly decreased IL-17RA levels, and inhibited the activation of p-STAT1, thereby alleviating cell apoptosis after MI. …”

Legacy effects of trampling on SOC, POC, and MOC​ by yanchun liu (19650631)

“…Our results showed that in 2015, soil inorganic nitrogen (SIN), fine root biomass (FRB), and microbial biomass C decreased significantly with increasing trampling intensity, whereas the negative effects weakened over the recovery period. …”

Impacts of winter climate change on northern forest understory carbon dioxide exchange determined by reindeer grazing by Noora Kantola (14263490)

“…To understand how reindeer grazing, coupled with changes in snow depth affects CO₂ exchange, we used recent snow treatments (ambient, reduced, and increased snow depth) combined with 25- and 55-year-old reindeer exclusions and the adjacent grazed areas in boreal and subarctic Scots pine forests that are main winter pastures for reindeer/caribou and cover a significant portion of boreal and subarctic landscapes. …”

Data Sheet 1_Antimycobacterial and immunomodulatory activities of sorafenib in a preclinical mouse model of TB infection through CD4+CD25low and CD8+CD25low effector T cells.pdf by Raju S. Rajmani (11134060)

“…In the current study, we documented a new immune modulatory characteristic of sorafenib that, upon SRB treatment, markedly increased effector T cells (Teff - CD4⁺CD25^low and CD8⁺CD25^low) activity and decreased regulatory T cells, the immunosuppressive T cells (Treg- CD4⁺CD25^high and CD8⁺CD25^high) function. …”

Data Sheet 2_Antimycobacterial and immunomodulatory activities of sorafenib in a preclinical mouse model of TB infection through CD4+CD25low and CD8+CD25low effector T cells.pdf by Raju S. Rajmani (11134060)

“…In the current study, we documented a new immune modulatory characteristic of sorafenib that, upon SRB treatment, markedly increased effector T cells (Teff - CD4⁺CD25^low and CD8⁺CD25^low) activity and decreased regulatory T cells, the immunosuppressive T cells (Treg- CD4⁺CD25^high and CD8⁺CD25^high) function. …”

Table1_Leishmania major surface components and DKK1 signalling via LRP6 promote migration and longevity of neutrophils in the infection site.docx by Olivia C. Ihedioha (19925886)

“…Relative to infected BALB/c mice, a significant reduction in parasite load was observed in both LRP6^NKO and LRP6^NKO DKK1^PKO infected mice. …”

SEAwise synthetic summary report of the findings of WP4 on changes to the ecosystem impacts of fishing in response to spatial management for online tool by Anna Rindorf (6217391)

“…The management scenarios investigated included fishing scenarios with different effort levels, closed areas and changes in relative effort of passive and active gears. We investigated whether scenarios with a higher proportion of landed stocks in good status also had a higher proportion of other ecological indicators in good status and the degree to which more restrictive, and risk adverse, management scenarios provided lower yields under current or future climate scenarios.…”

Supplementary Material for: Supportive care for common conditions in small vulnerable newborns and term infants: the evidence by Jiang L. (4145290)

“…Kangaroo mother care (KMC) significantly reduced SVN’s mortality by discharge. Early erythropoiesis stimulating agent lowered SVN’s risk of receiving blood transfusion. …”

Focus group guide. by Judite Blanc (22559981)

“…These disparities include lower life expectancy (64.8 vs. 82.3 years) and higher infant and maternal mortality rates. …”

Data Sheet 1_Characteristics of gut microbiota in Penaeus vannamei shifted with elevated salinity.docx by Bo Wang (86769)

“…The alpha diversity of the gut bacterial community of shrimp decreased with salinity. Significant differences in the composition and abundance of the core gut bacterial taxa were observed among ponds with varying salinity, and only 13 shared core operational taxonomic units (OTUs) were identified; the abundance of potential opportunistic pathogens decreased significantly in hypersaline environments. …”

Data Sheet 2_Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer.docx by Yanxian Gao (20555714)

“…Subsequent in vitro experiments demonstrated that silencing APOC1 reduced the generation of tumor-associated macrophages (TAMs) with an M2 phenotype while significantly decreasing the proliferation, invasion, and migration of MDA-MB-231 and MDA-MB-468 breast cancer cell lines.…”

Data Sheet 1_Integrating single-cell RNA-seq and bulk RNA-seq to explore prognostic value and immune landscapes of methionine metabolism-related signature in breast cancer.csv by Yanxian Gao (20555714)

“…Subsequent in vitro experiments demonstrated that silencing APOC1 reduced the generation of tumor-associated macrophages (TAMs) with an M2 phenotype while significantly decreasing the proliferation, invasion, and migration of MDA-MB-231 and MDA-MB-468 breast cancer cell lines.…”

Supplementary Material for: Abnormal Magnetic Resonance Imaging in the Medial Prefrontal Cortex Following Prenatal Alcohol Exposure and Placental Insufficiency in a Preclinical Mod... by figshare admin karger (2628495)

“…In the corpus callosum, the prenatal exposure/insult significantly decreased the AD (p<0.05; PAE+PI AD: 5.00x10-4 ± 4.60x10-5 mm2/s). …”

Shift in the Microbial Community Composition in Lake Wetland Sediments in the Source Region of the Yellow River Linked to Environmental Factors by Hexing Qi (20730615)

“…<p>The source region of the Yellow River, as the main flow-producing area, contributes more than 35% of the total flow of the Yellow River. Here, we surveyed the spatial distribution of the bacterial and fungal communities in the 17 sedimental sites of Longyangxia Valley and Donggi Conag Lake within the source region of the Yellow River. …”

Basal HLH-30 activity is not accompanied by enriched nuclear localization and declines during neuronal aging. by Ruiling Zhong (22339779)

“…<b>(E, F)</b> A fluorescent reporter of <i><i>rab-7</i></i> transcription shows that PVD-specific <i><i>rab-7</i></i> transcription increases in early-adults (Day 3) and decreases during aging in WT. In the <i><i>hlh-30</i></i> mutant, the PVD-specific <i><i>rab-7</i></i> transcription level is lower compared to WT at the same age, and there is no difference between Days 0 and 3. …”