Table 4_Comparative microbiome analysis of paired mucosal and fecal samples in Korean colorectal cancer patients.docx by Younggwang Kim (21562529)

“…However, few studies have examined tumor-associated microbial dynamics in Korean CRC patients using both mucosal and fecal samples.</p>Methods<p>We analyzed paired fecal and mucosal samples from 30 Korean CRC patients aged 60–80 years before and after surgery. …”

Improved antidiabetic potential of quercetin-loaded chitosan–lecithin nanoparticles for effective glycaemic control by Mohammad Zaki Ahmad (13117814)

“…However, its clinical use is limited by poor solubility and bioavailability. We developed the QTN loaded chitosan–lecithin nanoparticles (QTN/LCHS-NPs) to enhance its therapeutic profile.…”

Table_1_Diffusion and functional MRI reveal microstructural and network connectivity impairment in adult-onset neuronal intranuclear inclusion disease.docx by Rui Zhu (305217)

“…</p>Results<p>Compared with the HCs, NIID patients showed reduced mean kurtosis (MK), radial kurtosis (RK), axial kurtosis (AK), and kurtosis fractional anisotropy (KFA) values in deep gray matter regions. Significantly decreased MK, RK, AK, KFA and fractional anisotropy (FA), and increased mean diffusivity (MD) values were observed in extensive white matter fiber tracts. …”

Supplementary Material for: Perioperative Blood Pressure Management Recommendations in Pediatric Pheochromocytoma: A 10-Year Narrative Review by Ambarsari C.G. (16518681)

“…Nevertheless, mortality rates decreased significantly in the latter half of the twentieth century due to effective perioperative blood pressure (BP) management. …”

Table 1_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”

Data Sheet 1_Distribution of different plant life forms on tropical islands: patterns and underlying mechanisms.docx by Chengfeng Yang (3333489)

“…Introduction<p>Island biogeography theory posits that both island area and isolation significantly influence species distribution patterns and community structure. …”

DataSheet1_Engineered myeloid precursors differentiate into osteoclasts and resorb heterotopic ossification in mice.docx by Cameron Rementer (20310858)

“…Once symptomatic, HO causes pain, limited mobility and decreased quality of life. Current treatments are limited and have significant complications with high recurrence rates, underscoring the need for improved therapeutic interventions. …”

Tobacco and alcohol use are the risk factors responsible for the greatest burden of head and neck cancers: a study from the Global Burden of Disease Study 2019 by Yue Yuan (113839)

“…To better understand how these risk factors manifest differently across various head and neck tumor types, we utilized data from the GBD database to conduct an in-depth analysis.…”

Supplementary file 1_Transcriptional and neurotransmitter signatures of cerebral spontaneous neural activity in nurses with burnout.docx by Chun-Mei Song (21716903)

“…</p>Results<p>Nurses with burnout exhibited significantly decreased precuneus fALFF and reduced precuneus-right dorsolateral prefrontal cortex (DLPFC) FC compared to controls. …”

Supplementary file 1_Gut microbiome and serum metabolome alterations in osteosarcoma patients.docx by Chao Li (145513)

“…This study aimed to characterize the gut microbiota and serum metabolite profiles in osteosarcoma patients, evaluate the diagnostic potential of gut microbiota and serum metabolites for osteosarcoma, and explore their correlations.</p>Methods<p>We collected 128 fecal and 181 serum samples from osteosarcoma patients, paired with matched healthy controls. 16S rRNA sequencing and untargeted metabolomics were applied to analyze gut microbiota and serum metabolism with significantly altered abundance in patients with osteosarcoma. …”

Table 1_Predicting psychiatric risk: IgG N-glycosylation traits as biomarkers for mental health.xls by Yinchun Lv (18181816)

“…Background<p>Growing evidence suggests that chronic inflammation, resulting from intricate immune system interactions, significantly contributes to the onset of psychiatric disorders. …”

Data Sheet 1_Assessing the evolution of infectious disease preparedness among a province with poor economy in China in the wake of COVID-19.docx by Huaying Liu (8312517)

“…</p>Methods<p>Utilizing random sampling, we conducted questionnaire surveys among primary care physicians from Guangxis primary medical institutions in June 2019 and October 2022, and analyzed the data with SPSS software.…”

Table 1_ADAM8 in macrophages exacerbates sepsis-induced cardiomyopathy by impeding efferocytosis.docx by Zhenjun Ji (11050644)

“…RNA transcriptome sequencing was conducted on left ventricular tissues sourced from ADAM8 CKO mice, as well as on RAW264.7 cell lines that were treated with both ADAM8 knockdown (KD) lentivirus and LPS.</p>Results<p>Here, we demonstrate that ADAM8 expression is significantly upregulated in cardiac macrophages of SICM mice using single-cell transcriptomics and immunofluorescence. …”

Data Sheet 1_Gut microbiota is involved in the exacerbation of adrenal glucocorticoid steroidogenesis in diabetic animals by activation of the TLR4 pathway.pdf by Nathalia Santos Magalhães (14131047)

“…TAK-242 significantly decreased the overexpression of adrenocorticotropic hormone receptor and 11β-hydroxysteroid dehydrogenase type 1 in the adrenal glands of diabetic mice. …”

Table 1_Autoimmune thyroid disease and human health: a systematic review of Mendelian randomization studies.xlsx by Peijin Li (220400)

“…MR analyses indicated that AITD significantly increased the risk of coronary atherosclerosis, deep venous thrombosis, chronic obstructive pulmonary disease, major depression, diabetic neuropathy, carpal tunnel syndrome, neuromyelitis optica spectrum disorder, diabetic retinopathy, childhood absence epilepsy, rheumatoid arthritis, systemic lupus erythematosus, psoriatic arthritis, inflammatory bowel disease, crohn's disease, vitiligo, myasthenia gravis, alopecia areata, type 1 and type 2 diabetes, sarcoidosis, frozen shoulder, drug eruptions, cataract, early age-related macular degeneration, pernicious anemia, Helicobacter pylori infection, temporomandibular disorders, migraine, frailty, primary biliary cholangitis, knee osteoarthritis, gout, and osteoporosis, while decreasing the risk of lung cancer, polyneuropathies, allergic rhinitis, telomere length, and serum vitamin A levels. …”

Supplementary Material for: Atypical COVID-19-related Acute Macular Neuroretinopathy with Progression resulting in Severe Vision Loss by Weinberger E.M (20394746)

“…Introduction: We review the clinical course of a patient with decreased vision in the setting of COVID-19 infection consistent with an atypical presentation of acute macular neuroretinopathy (AMN). …”

Table 3_Mitochondrial dysfunction signatures in idiopathic primary male infertility: a validated proteomics-based diagnostic approach.docx by Raneen Sawaid Kaiyal (20418824)

“…Analysis of expression levels of three mitochondrial proteins known to combat oxidative stress revealed that peroxiredoxin-5 (PRDX5) and superoxide dismutase 2 (SOD2), but not glutathione disulphide reductase, were significantly decreased in patient samples compared with those in fertile-donor samples.…”

<i>Neisseria</i> species on the tonsillar surface predicts favorable clinical outcomes in patients with Immunoglobulin A nephropathy who underwent tonsillectomy by Ryosuke Sato (615801)

“…However, the bacteria involved in the pathogenesis of IgAN have not been fully elucidated. In this study, we compared the differences in tonsillar bacterial flora between IgAN (<i>n</i> = 101) and recurrent tonsillitis (RT) (<i>n</i> = 117) based on swab cultures from tonsillar surfaces and the center of the tonsils. …”

Data Sheet 1_Exploring the effects of exercise on T cell function and metabolism in cancer: a scoping review protocol.pdf by J. L. Low (22141795)

“…Immunotherapy strategies that leverage the anti-cancer T cell response have significantly advanced therapeutic approaches to cancer treatment. …”

Table 1_Behavioral alterations in antibiotic-treated mice associated with gut microbiota dysbiosis: insights from 16S rRNA and metabolomics.xlsx by Asma Bibi (12057986)

“…The KEGG enrichment analysis of serum and brain samples showed that amino acid metabolism pathways, such as tryptophan metabolism, threonine metabolism, serotonergic synapsis, methionine metabolism, and neuroactive ligand-receptor interaction, were significantly decreased in antibiotic-treated mice. Our study demonstrates that long-term antibiotic use induces gut dysbiosis and alters metabolic responses, leading to the dysregulation of brain signaling molecules and anxiety-like behavior. …”