The protective effects of neferine against paracetamol-induced liver injury are associated with the activation of SIRT1/Nrf2/HO-1 signaling pathway and inhibition of NF-kappa B/TNF... by Mohammed A. Altowijri (22461945)

“…<p>Drug-induced hepatotoxicity is a significant public health issue that influences the development of novel pharmaceutical therapies and the retraction of numerous promising medications from the market. …”

Unraveling the Effects of Epigallocatechin-3-gallate on Hepatocellular Carcinoma Cells: A Comparative Analysis of Monolayer vs Multicellular Tumor Spheroids by Mariana dos Reis Simpronio (21876938)

“…The cell culture condition influenced EGCG effects on gene expression and cell viability, with more significant effects in monolayer than in MTS. After 15 days, control MTS showed cellular dissociation, whereas EGCG-treated MTS showed decreased cell viability and no growth. …”

Table 1_Correlation between lactate/albumin ratio and 28-day mortality in sepsis-associated acute kidney injury patients.docx by Susu He (10361615)

“…The Kaplan–Meier curves showed that participants having elevated LAR exhibited significantly decreased survival rates. Cox proportional hazards models showed that higher LAR was related to higher 28-day death rate in SA-AKI patients (HR: 1.224, 95% CI: 1.160–1.291, p < 0.001). …”

Table 1_Time trends in mechanical thrombectomy (2017–2021): do real-world data reflect advances in evidence?.docx by Christoph Riegler (3554054)

“…Background<p>In recent years, we have witnessed a continuous, evidence-based expansion of indications for endovascular therapy (EVT) in the treatment of ischaemic stroke, driven by advancements in extended time windows and target vessel occlusion. …”

DataSheet1_Effects of fertilization on litter decomposition dynamics and nutrient release in orchard systems.docx by Huayue Nie (20385747)

“…Although adding nutrients decreased soil enzyme activity later in the decomposition process, no significant correlation was detected between enzyme activity and the remaining mass. …”

Supplementary file 1_Does body weight support improve neural and biomechanical measures during treadmill gait in children with unilateral cerebral palsy?.docx by Rajit Banerjee (22481089)

“…Beta band EEG activation from 0% to 20% BWS showed a significant triple interaction increasing in the non-dominant and decreasing in the dominant hemisphere in TD, while increasing in both in CP. …”

Supplementary Tables S1 and S2 by Thomas Clanton (9323303)

“…We also tested the secretory response to buffer containing 1% sterile mouse plasma. …”

Data_Sheet_1_The association between Geriatric Nutritional Risk Index and KSD disease: results from National Health and Nutrition Examination Survey 2007–2018.ZIP by Zhicheng Tang (7010534)

“…</p>Conclusion<p>The study underscores a significant, albeit nonlinear, association between elevated GNRI levels and decreased KSD prevalence. …”

Data_Sheet_1_The association between Geriatric Nutritional Risk Index and KSD disease: results from National Health and Nutrition Examination Survey 2007–2018.ZIP by Zhicheng Tang (7010534)

“…</p>Conclusion<p>The study underscores a significant, albeit nonlinear, association between elevated GNRI levels and decreased KSD prevalence. …”

Competition constrains the resistance and recovery of fungi to heat stress under low nutrient concentration by Jingjing Shi (20738168)

“…Here, we investigated how competitive interactions between fungi affect their resistance and recovery to a heat event. …”

Supplementary Material for: Thyroid hormone clearance in the paraventricular nucleus of male mice regulates lean mass and physical activity by Wu Z. (4429111)

“…We accomplished DIO3 genetic inactivation via stereotaxic injection of the AAV-cre vector into adult mice homozygous for a “floxed” Dio3 allele. …”

Table 1_CyTOF reveals platelet subtype changes predicting the efficacy of combined immunotherapy and targeted therapy in liver cancer.docx by Wenjing Wang (181404)

“…Notably, this subpopulation decreased with tumor remission and increased with tumor progression.…”

Key model formula. by Chayanit Mahasing (19688403)

“…In addition, we conducted a one-way sensitivity analysis by adjusting R0 from 1.8 to 3.0 in all scenarios (epidemic stage) and by decreasing the vaccination cost by 50% at the end of the first year to reflect the current policy direction to enhance domestic vaccine production. …”

Model framework. by Chayanit Mahasing (19688403)

“…In addition, we conducted a one-way sensitivity analysis by adjusting R0 from 1.8 to 3.0 in all scenarios (epidemic stage) and by decreasing the vaccination cost by 50% at the end of the first year to reflect the current policy direction to enhance domestic vaccine production. …”

Supplementary file 1_Emergency department overcrowding: first Swiss application of the Emergency Department Work Index and risk factors for overcrowding.pdf by Aline Herzog (22589720)

“…</p>Methods<p>In this retrospective analysis, we included consecutive ED visits at a tertiary care hospital between 1st December and 31st December 2016. …”

Data Sheet 1_Integrating groundwater pumping data with regression-enhanced random forest models to improve groundwater monitoring and management in a coastal region.pdf by Jamie Kim (14893220)

“…Using the trained RERF model, we generated 90 m spatial resolution WTD anomaly maps for New Jersey for January and July 2015, showing areas of increasing and decreasing WTD. …”

Image1_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tiff by Khushbu Priya (11863559)

“…And to elucidate the mechanism involved therein.</p>Methods<p>We investigated the immunomodulatory effects of DW and IW on NETosis in SLE. …”

Essential model parameters. by Chayanit Mahasing (19688403)

“…In addition, we conducted a one-way sensitivity analysis by adjusting R0 from 1.8 to 3.0 in all scenarios (epidemic stage) and by decreasing the vaccination cost by 50% at the end of the first year to reflect the current policy direction to enhance domestic vaccine production. …”

Data Sheet 1_The CD38+HLA-DR+ T cells with activation and exhaustion characteristics as predictors of severity and mortality in COVID-19 patients.docx by Qiuyue Long (11381148)

“…The single-cell RNA sequencing (scRNA-seq) was applied to characterize the critical cell subset associated with prognosis and elucidate its phenotype in COVID-19.</p>Results<p>We revealed a significant increase in CD38⁺HLA-DR⁺ T cells in non-survivor COVID-19 patients, establishing them as an independent risk factor for 28-day mortality. …”

Image3_Dexamethasone and IFN-γ primed mesenchymal stem cells conditioned media immunomodulates aberrant NETosis in SLE via PGE2 and IDO.tif by Khushbu Priya (11863559)

“…And to elucidate the mechanism involved therein.</p>Methods<p>We investigated the immunomodulatory effects of DW and IW on NETosis in SLE. …”