Data Sheet 1_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.pdf حسب Linjie Peng (12553717)

"…</p>Results<p>Compared with the control group, TB001-treated recipients had significantly improved kidney allograft function, as evidenced by lower creatinine and 24-hour urine protein levels. …"

Table 1_Esmolol improves sepsis outcomes through cardiovascular and immune modulation.docx حسب Da Jing (404219)

"…Additionally, Esmolol treatment resulted in bidirectional regulation of T-cell counts, increasing CD4⁺ and CD8⁺ T-cell counts in patients with higher baseline immune function and decreasing these counts in patients with lower baseline levels (P < 0.01).…"

Table 1_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.docx حسب Jiayue Zhang (7832669)

"…Whereas, Singapore, South Korea, and Finland were lower than the global average. The APC model showed that the incidence increased significantly with the increase of age. …"

Data Sheet 1_Gut microbiota metabolite acetate mediates free fatty acid receptor 2 expression to alleviate atopic dermatitis.zip حسب Siqi Ye (9350531)

"…Acetate supplementation in AD mice significantly ameliorated 2,4-dinitrobenzene (DNCB)-induced dermatitis, as evidenced by reduced skin lesion severity, lower dermatitis scores, and decreased epidermal thickening. …"

Image 7_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

"…An area under the curve analysis using a random forest model based on fecal metagenomics, plasma metabolomics, and tissue metabolomics revealed that gut bacteria, plasma, and tissue metabolites were effective in distinguishing between MK and NS groups. Decreased Bacteroides plebeius could lower uracil levels, altering systemic lipid metabolism, which may change the metabolic phenotype of secretory reticular fibroblasts in wounds, potentially leading to MK. …"

Image 6_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

"…An area under the curve analysis using a random forest model based on fecal metagenomics, plasma metabolomics, and tissue metabolomics revealed that gut bacteria, plasma, and tissue metabolites were effective in distinguishing between MK and NS groups. Decreased Bacteroides plebeius could lower uracil levels, altering systemic lipid metabolism, which may change the metabolic phenotype of secretory reticular fibroblasts in wounds, potentially leading to MK. …"

Table 4_Effect of natural bioactive compounds on growth and welfare in Octopus vulgaris paralarvae.xlsx حسب M. Virginia Martín (6321047)

"…Although enzymatic antioxidant responses such as catalase (CAT) and superoxide dismutase (SOD) were unaffected, glutathione S-transferase (GST) activity significantly decreased in the BCO group, suggesting a reduced need for detoxification due to lower oxidative stress. …"

Supplementary file 1_Effects of education level on natural language processing in cardiovascular health communication.xlsx حسب Stanley Joseph (19282225)

"…</p>Results<p>Readability decreased significantly with increasing education level across all models (p < 0.001). …"

Table 3_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx حسب Jiayue Zhang (7832669)

"…Whereas, Singapore, South Korea, and Finland were lower than the global average. The APC model showed that the incidence increased significantly with the increase of age. …"

Data Sheet 1_Changed expression of placental transporters and disrupted epigenetic patterns in a rat model of schizophrenia.pdf حسب Péter Szatmári (22611392)

"…</p>Results<p>Reduced placental P-gp expression was identified in late pregnancy, while the placental BCRP expression upregulation was observed before term in schizophrenia. Significantly lower fetal fexofenadine plasma concentration was measured on the 21st and 22nd days of pregnancy compared to the mother; in contrast, the fexofenadine concentration was similar in the schizophrenia-like mother and fetus. …"

Image 8_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

"…An area under the curve analysis using a random forest model based on fecal metagenomics, plasma metabolomics, and tissue metabolomics revealed that gut bacteria, plasma, and tissue metabolites were effective in distinguishing between MK and NS groups. Decreased Bacteroides plebeius could lower uracil levels, altering systemic lipid metabolism, which may change the metabolic phenotype of secretory reticular fibroblasts in wounds, potentially leading to MK. …"

Table 1_Effects of salinity stress on morphological structure, physiology, and mRNA expression in different wheat (Triticum aestivum L.) cultivars.doc حسب Xiaohui Sun (520181)

"…Further investigation showed the salt-tolerant phenotypes of QM6 were accompanied by decreases of reactive oxygen species (ROS) content, and lower antioxidant enzyme activities after salt treatment compared with CS. …"

Image 5_Integrative multiomics analysis reveals association of gut microbiota and its metabolites with susceptibility to keloids.jpeg حسب Dang Li (16400478)

"…An area under the curve analysis using a random forest model based on fecal metagenomics, plasma metabolomics, and tissue metabolomics revealed that gut bacteria, plasma, and tissue metabolites were effective in distinguishing between MK and NS groups. Decreased Bacteroides plebeius could lower uracil levels, altering systemic lipid metabolism, which may change the metabolic phenotype of secretory reticular fibroblasts in wounds, potentially leading to MK. …"

Table 6_Age-Period-Cohort analysis and 2036 projections of the burden of ischemic stroke in Finland, Korea, Singapore and China, 1990–2021.xlsx حسب Jiayue Zhang (7832669)

"…Whereas, Singapore, South Korea, and Finland were lower than the global average. The APC model showed that the incidence increased significantly with the increase of age. …"

Table 3_GLP-1 and glucagon receptor dual agonism ameliorates kidney allograft fibrosis by improving lipid metabolism.xls حسب Linjie Peng (12553717)

"…</p>Results<p>Compared with the control group, TB001-treated recipients had significantly improved kidney allograft function, as evidenced by lower creatinine and 24-hour urine protein levels. …"

Data Sheet 1_Ibrutinib enhances the bias of T cell responses towards staphylococcal superantigens sustaining inflammation in chronic lymphocytic leukaemia.pdf حسب Fisal Tantoush (20936264)

"…We found that ibrutinib-treated patients had less naive CD8+ T cells (p=0.0348), more checkpoint receptor (TIM-3) expression in memory T cells (p<0.0001), and lower IFNγ/cytokine responses in patient T cells (p≤0.0298). …"

Prognostic value of miR-378c in hepatocellular carcinoma and its regulatory effect on tumor progression حسب Yuanjie Bao (21075400)

"…</p> <p>Serum miR-378c were remarkably lower in HCC patients than in cirrhosis patients and healthy controls (<i>p</i> < 0.001). …"

Image 1_Immunosuppressants in dermatology on vaccine immunogenicity: a prospective cohort study of pemphigus patients in the pandemic.tif حسب Kun-Lin Lu (7256960)

"…Intriguingly, we found that daily dosages of 100 mg or more of azathioprine were linked to significantly decreased anti-viral T-cell responses induced by the vaccination (mean of fold change [SD]; higher azathioprine dosage = 0.70 [0.61] folds vs. lower azathioprine dosage = 2.11 [1.03] folds; p = 0.044).…"

Data Sheet 1_Effect of cultivation feed diet using local food processing by-products on the growth and flavor factor in the Malabar grouper Epinephelus malabaricus.docx حسب Makoto Takahashi (386772)

"…</p>Results<p>FW-D-fed fish showed slightly lower growth performance, possibly due to decreased protein content. …"

Data Sheet 1_Andrographis paniculata restores gut health by suppressing inflammation and strengthening mucosal immunity.pdf حسب Vidushi Tyagi (14022240)

"…In vivo studies demonstrated reduced bacterial colonization in the spleen, lower systemic markers of infection, and restoration of intestinal homeostasis. …"