supplementary figure: Osimertinib inhibits the MYLK4-mediated phosphorylation of CDKAL1 to suppress stemness and chemoresistance in rhabdomyosarcoma by Takuto Itano (16830105)

“…The RT‒PCR data are presented as the means ± SDs (n = 3). Statistical significance: ns, p ≥ 0.05. …”

Data Sheet 1_Cannabinoid receptor 2 selective agonist ameliorates adjuvant-induced arthritis by modulating the balance between Treg and Th17 cells.docx by Na Tian (296333)

“…</p>Results<p>HU-308 reduced paw swelling, lowered spleen index, and preserved joint integrity in AIA mice, mitigating inflammatory cell infiltration and bone erosion. …”

Combating Chemoresistance in Breast Cancer: Exploring Tumor Microenvironment, Combination Therapies, and Drug Repurposing Strategies by Shazia Sofi (17764488)

“…Chemoresistance in cancer can arise from a variety of molecular mechanisms, including active drug expulsion (drug efflux), decreased drug uptake, enhanced DNA repair mechanisms, the ability of cancer cells to evade programmed cell death (apoptosis), the diversity in the population of cancer cells within a tumor (tumor heterogeneity), and significant alterations in the tumor microenvironment (TME), where interactions between cancer cells, cancer-associated fibroblasts, immune cells, and the extracellular matrix contribute to a supportive environment that allows tumors to survive treatment and escape therapy. …”

Table 1_Overcoming tet(X)-harboring tigecycline resistance: a study on the efficacy of tigecycline-apramycin combinations.docx by Juan Liu (6492)

“…</p>Methods<p>In this study, we evaluated the synergism of tigecycline combining with other antibiotics as a means of overcoming the tet(X)-mediated resistance in Acinetobacter spp. …”

Zika virus replicates efficiently in the zebrafish model and induces morphological defects. by Aïssatou Aïcha Sow (20371233)

“…<i>N</i> = 3). Data are shown as means ± SEM. **** P ≤ 0.0001; ns = not significant; one-way ANOVA. …”

DataSheet1_Strict biennial lifecycle and anthropogenic interventions affect temporal genetic differentiation in the endangered endemic plant, Pedicularis hallaisanensis.docx by Seongjun Kim (1993465)

“…Other cluster analyses also showed that a microhabitat under historical anthropogenic interventions contained lowered genetic diversity due to a decreased genetic distance between odd-year and even-year flowering cohorts (p < 0.05). …”

Data Sheet 1_Elevated Galectin-3 levels in the tumor microenvironment of ovarian cancer – implication of ROS mediated suppression of NK cell antitumor response via tumor-associated... by Veronika Karlsson (20457788)

“…In co-cultures with NK cells and K562 target cells, we observed that Galectin-3-induced production of reactive oxygen species in neutrophils resulted in decreased NK cell viability and lowered anti-tumor responses.…”

Table 3_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.docx by Jia-Yi Wang (490704)

“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”

Table 2_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.xlsx by Jia-Yi Wang (490704)

“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”

Table 1_Do the diagnosis-related group payment reforms have a negative impact?—an empirical study from Western China.xlsx by Jia-Yi Wang (490704)

“…In the treatment group hospitals, the primary beneficiaries of the reform were urban employees’ basic medical insurance patients, whose costs decreased by 4.9% (p < 0.01), with a non-significant effect on out-of-pocket payment patients and free medical care patients; the hospitals in the treatment group tended to reduce the use of Chinese medicine unique diagnostic and therapeutic means and increase the proportion of western medicine treatments under the pressure of the supremacy of costs.…”

Supplementary Material: Spent hemp biomass as a feed ingredient for beef steers: effects on performance, blood parameters, behavior, cannabinoid residues, and consumer exposure lev... by Agung Irawan (14145081)

“…However, the potential accumulation of cannabinoids in animal products, particularly the psychoactive compound ∆⁹-tetrahydrocannabinol (Δ⁹-THC), remains a significant barrier to the legalization of SHB as a feed ingredient for livestock. …”

OVD-induced transient OHT in mice leads to RGC loss and astrocyte reactivity. by Weiran Huang (8934899)

“…<p>(A) OVD injections led to IOP increase, with values presented as means ± SD. IOP decreased 6 hours post-injection and by day 1 had returned to near baseline levels. …”

Heart looping variations in <i>Notch3</i> and <i>Nodal</i> compound mutants. by Tobias Holm Bønnelykke (20968460)

“…</i> Filled and empty arrowheads point to curved and straight outflow tract, respectively. Means and standard deviations are shown. L, Left; LV, left ventricle; n.s., non-significant; R, Right; RV, right ventricle. …”

Table 1_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Estimates are presented as means with 95% uncertainty intervals (UIs).</p>Results<p>In 2021, the global age-standardized prevalence rate of HHD was 148.32 (95% UI: 117.32, 186.28) per 100,000 population. …”

Table 4_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Estimates are presented as means with 95% uncertainty intervals (UIs).</p>Results<p>In 2021, the global age-standardized prevalence rate of HHD was 148.32 (95% UI: 117.32, 186.28) per 100,000 population. …”

Image 1_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.tif by Ning An (618997)

“…Estimates are presented as means with 95% uncertainty intervals (UIs).</p>Results<p>In 2021, the global age-standardized prevalence rate of HHD was 148.32 (95% UI: 117.32, 186.28) per 100,000 population. …”

Table 3_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Estimates are presented as means with 95% uncertainty intervals (UIs).</p>Results<p>In 2021, the global age-standardized prevalence rate of HHD was 148.32 (95% UI: 117.32, 186.28) per 100,000 population. …”

Table 2_Unveiling the global impact of hypertensive heart disease among individuals aged ≥ 65 years: metabolic risk factors and future projections for 2050.xlsx by Ning An (618997)

“…Estimates are presented as means with 95% uncertainty intervals (UIs).</p>Results<p>In 2021, the global age-standardized prevalence rate of HHD was 148.32 (95% UI: 117.32, 186.28) per 100,000 population. …”

Supporting data for “Androgen receptor modulates chemotherapy response in breast cancer” by Chanping You (9067448)

“…TRIM37 overexpression decreased palbociclib sensitivity, while its knockdown enhanced sensitivity and attenuated the effect of AR on RB1 levels and drug response, establishing TRIM37 as a novel E3 ligase that bound RB1 via its MATH and C-terminal domains.…”

Sound evoked cortical activity across vigilance states before and after NOE. by Linus Milinski (10532121)

“…Asterisks for panels <b>E-F</b> represent statistical significance p values *<0.05, **<0.01, ***<0.001 (GLMM). …”