Data Sheet 1_Case Report: Metabolic alterations and cholesterol esterification in a low-grade diffuse astrocytoma patient who progressed to glioblastoma at recurrence.docx by Omkar B. Ijare (22274167)

“…Particularly, IDH wildtype (IDHwt) diffuse astrocytomas harboring TERT promoter (TERTp) mutations, classified as molecular GBM under the 2021 WHO classification, may exhibit distinct metabolic and epigenetic features compared to histological WHO Grade 4 GBMs. Here, we conducted a detailed metabolomic comparison of tumor specimens from a patient initially diagnosed with WHO Grade 2 IDHwt diffuse astrocytoma carrying TERTp mutation, who subsequently progressed to a histologically confirmed WHO Grade 4 GBM upon recurrence.…”

Sketches of the two circuits used. by Lars-Olav Harnisch (22008639)

“…In the design of circuit-2, MP exceeded the 12 J/min threshold in both lung simulators at elevated RR and could only be decreased through valve closure followed by a consequential hypoventilation in one simulator.…”

Table 1_Abnormal subthalamic nucleus functional connectivity and machine learning classification in Parkinson’s disease: a multisite functional magnetic resonance imaging study.doc... by Bin Qin (544949)

“…Introduction<p>Parkinson’s disease (PD) is a progressive neurodegenerative disorder imposing a significant global burden, characterized by motor dysfunction linked to aberrant basal ganglia activity. …”

Image 1_Modulation of VR-HMD-induced cybersickness using cathodal transcranial direct current stimulation: a functional near-infrared spectroscopy study.jpeg by Seong Ho Yun (22686965)

“…Results showed that cathodal tDCS significantly reduced nausea-related cybersickness symptoms compared to sham stimulation (p < 0.05). fNIRS analysis revealed decreased oxyhemoglobin concentrations in the bilateral superior parietal lobule and angular gyrus following cathodal tDCS, indicating reduced cortical activity in these regions. …”

Image 2_Modulation of VR-HMD-induced cybersickness using cathodal transcranial direct current stimulation: a functional near-infrared spectroscopy study.jpeg by Seong Ho Yun (22686965)

“…Results showed that cathodal tDCS significantly reduced nausea-related cybersickness symptoms compared to sham stimulation (p < 0.05). fNIRS analysis revealed decreased oxyhemoglobin concentrations in the bilateral superior parietal lobule and angular gyrus following cathodal tDCS, indicating reduced cortical activity in these regions. …”

Table 1_Evaluating the global, regional, and national burden of congenital heart disease in infants younger than 1 year: a 1990–2021 systematic analysis for the GBD study 2021.docx... by Lili Deng (152262)

“…</p>Interpretation<p>CHD remains a significant and rapidly escalating global challenge in child health. …”

Data Sheet 2_Co-administration of vitamin D and N-acetylcysteine to modulate immunosenescence in older adults with vitamin D deficiency: a randomized clinical trial.pdf by Samira Rastgoo (15252703)

“…Background<p>Immunosenescence is an important factor in the impaired immune response in older adults and plays a significant role in the development of biological aging. …”

Data Sheet 1_Co-administration of vitamin D and N-acetylcysteine to modulate immunosenescence in older adults with vitamin D deficiency: a randomized clinical trial.pdf by Samira Rastgoo (15252703)

“…Background<p>Immunosenescence is an important factor in the impaired immune response in older adults and plays a significant role in the development of biological aging. …”

Map showing the intervention and control LGAs. by Chinwe C. Eze (8787503)

“…At baseline, respondents in the intervention group had a significantly higher adjusted mean total score on the SARI Stigma Scale compared to the control group, with an adjusted mean difference of 10.75 (95% CI: 8.05–13.46, p < 0.000). …”

Consort diagram. by Chinwe C. Eze (8787503)

“…At baseline, respondents in the intervention group had a significantly higher adjusted mean total score on the SARI Stigma Scale compared to the control group, with an adjusted mean difference of 10.75 (95% CI: 8.05–13.46, p < 0.000). …”

<b>Dataset of a </b><b>phase Ib clinical study: </b><b>rapid regression of high-risk carotid hemorrhagic </b><b>plaques with sonodynamic therapy</b> by Ye Tian (22423790)

“…The primary endpoint demonstrated a significant decrease in maximum wall thickness (MaxWT) at 1 month post-SDT in all plaques, particularly IPH plaques. …”

Table 1_Inverse association between atherogenic index of plasma and testosterone in US adult males: A large cross-sectional study from the NAHNES 2011–2016.xlsx by Tanjian Li (20431610)

“…Serum lipids have been proven to influence serum testosterone levels, and AIP is a significant marker of lipid levels. We hypothesize that AIP may have a specific relationship with testosterone. …”

Participants’ characteristics. by Aizhan Zabirova (21446781)

“…A logistic regression analysis indicated that acceptance of the facility and good mental health significantly increased the likelihood of trusting information provided by the public authorities, while concerns about genetic risks and negative images significantly decreased it. …”

Video 1_Safety and effectiveness of a new minimally invasive glaucoma surgery namely trabeculotome tunneling trabeculoplasty in primary open-angle glaucoma.mp4 by Suzhen Wang (163752)

“…Postoperative IOP significantly decreased at all follow-up points except at 1 week (p < 0.05). …”

Video 1_Efficacy of a novel surgical approach: sutureless correction of conjunctivochalasis using new conjunctival forceps combined with high-frequency electrocautery.mp4 by Tingting Song (575707)

“…OSDI scores showed no difference between preoperative (38.54) and 1-week postoperative (41.67) values (p=0.922), but significantly decreased by 1 month (16.67, p<0.001). …”

Data Sheet 1_Efgartigimod for the treatment of immune checkpoint inhibitor-associated myocarditis complicated with impending crisis state of myasthenia gravis: a case report.pdf by Mingjia Lu (21593324)

“…Treatment with efgartigimod (10 mg/kg) significantly improved myasthenic symptoms, with Myasthenia Gravis–Activities of Daily Living (MG-ADL) and Quantitative Myasthenia Gravis (QMG) scores decreasing from 11 to 5 and 26 to 11, respectively. …”

Data Sheet 1_Alterations in brain function in patients with post-stroke cognitive impairment: a resting-state functional magnetic resonance imaging study.docx by Kaiyue Han (11743982)

“…Background<p>Cognitive impairment is a common dysfunction following stroke, significantly affecting patients’ quality of life. …”

Data Sheet 2_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf by Meng Yi (7853249)

“…Introduction<p>Low back pain (LBP), primarily driven by intervertebral disc degeneration (IDD), imposes a significant global health burden. While type 2 diabetes mellitus (T2DM) is a recognized risk factor for IDD, the shared molecular mechanisms remain incompletely characterized.…”

Data Sheet 1_Multi-omics analysis and evidence of IL1R1 as a potential biomarker for diabetes-associated intervertebral disc degeneration.pdf by Meng Yi (7853249)

“…Introduction<p>Low back pain (LBP), primarily driven by intervertebral disc degeneration (IDD), imposes a significant global health burden. While type 2 diabetes mellitus (T2DM) is a recognized risk factor for IDD, the shared molecular mechanisms remain incompletely characterized.…”

Supplementary file 1_Changes of potential shorty-chain fatty acids producing bacteria in the gut of patients with spinal cord injury: a systematic review and meta-analysis.zip by Zaowei Zhong (20796020)

“…<p>Gut bacteria that potential produce short-chain fatty acids (SCFAs) influences the recovery of motor function in the host in patients with spinal cord injury (SCI). We aimed to conduct a review and meta-analysis of the literature on gut microbiota in SCI patients. …”