DataSheet1_Chitinase 1: a novel therapeutic target in metabolic dysfunction-associated steatohepatitis.zip by Jung Hoon Cha (19723588)

“…Additionally, OATD-01-treated mice had lower CHIT1, F4/80, and α-smooth muscle actin positivity, as well as significantly lower levels of inflammatory markers, pro-fibrotic genes, and matrix remodeling-related mRNAs than vehicle-treated mice. …”

Table 1_Assessment of platelet-to-white blood cell ratio on short-term mortality events in patients hospitalized with acute decompensated heart failure: evidence from a cohort stud... by Xin Huang (11077)

“…Further threshold analysis revealed a threshold point for PWR at 15.88, where a decrease in PWR below this threshold was significantly associated with increased risk of all-cause mortality (p for log-likelihood ratio test = 0.046). …”

Data Sheet 1_Isoform-specific vs. pan-histone deacetylase inhibition as approaches for countering glioblastoma: an in vitro study.docx by Ameya Joshi (1290186)

“…The non-specific inhibitor Vorinostat surprisingly promoted migration in the cells at its 2D IC50 value treatment, and none of the inhibitors was able to significantly decrease late resistance compared to untreated controls, indicating the need for the development of more potent HDAC inhibitors for monotherapy for GBM.…”

Data Sheet 1_Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank.pdf by Pia Leibold (21390134)

“…In a sensitivity analysis based on different racial subgroups, only White participants showed significant associations between the CYP3A5*3 variant and slightly higher DBP (β = 0.10 mmHg, 95% CI: 0.02 to 0.18, P = 0.01), as well as between genotype-predicted CYP3A5 activity score and slightly lower DBP (β = −0.10 mmHg, 95% CI: −0.18 to −0.02, P = 0.01). …”

A systematic review of the efficacy and safety of anti-amyloid beta monoclonal antibodies in treatment of Alzheimer’s disease by Akanksha Chhabra (71080)

“…Aducanumab resulted in a decrease of −0.39 (−22%). Bapineuzumab showed no significant benefit, with scores of 2.4 (2.8). …”

Table 1_Burden of esophageal cancer in global, regional and national regions from 1990 to 2021 and its projection until 2050: results from the GBD study 2021.docx by Chengcheng Zhang (725743)

“…</p>Conclusions<p>The global burden of EC remains significant, with ongoing challenges in regions such as Africa and East Asia. …”

SEAwise report on effects of spatial management measures suggested in SEAwise to safeguard species, habitats and choke species on fisheries selectivity and fuel cost by Francois Bastardie (6217991)

“…Under the FMSY scenario, the fuel consumption for all the fleets decreased significantly due to the decrease in fishing effort. …”

Data Sheet 1_Emotional prompting amplifies disinformation generation in AI large language models.docx by Rasita Vinay (21006911)

“…Impolite prompting resulted in a significant decrease in disinformation production across all models (davinci-002, 59%; davinci-003, 44%; and gpt-3.5-turbo, 28%) and a slight reduction for gpt-4 (94%).…”

Table 4_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.csv by Christian Ayala-Ortiz (15255371)

“…Through this approach, we achieved molecule-specific tracking of carbon transformations at unprecedented detail.…”

Supplementary file 1_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.docx by Christian Ayala-Ortiz (15255371)

“…Through this approach, we achieved molecule-specific tracking of carbon transformations at unprecedented detail.…”

Table 3_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.csv by Christian Ayala-Ortiz (15255371)

“…Through this approach, we achieved molecule-specific tracking of carbon transformations at unprecedented detail.…”

Table 2_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.csv by Christian Ayala-Ortiz (15255371)

“…Through this approach, we achieved molecule-specific tracking of carbon transformations at unprecedented detail.…”

Table 6_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.csv by Christian Ayala-Ortiz (15255371)

“…Through this approach, we achieved molecule-specific tracking of carbon transformations at unprecedented detail.…”

Table 7_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.csv by Christian Ayala-Ortiz (15255371)

“…Through this approach, we achieved molecule-specific tracking of carbon transformations at unprecedented detail.…”

Table 5_Tracing priming effects in palsa peat carbon dynamics using a stable isotope-assisted metabolomics approach.csv by Christian Ayala-Ortiz (15255371)

“…Through this approach, we achieved molecule-specific tracking of carbon transformations at unprecedented detail.…”

Table 1_Oxidative balance score is independently associated with reduced prevalence of sarcopenia among US adults with metabolic syndrome.docx by Miaohong Wang (8975903)

“…Restricted cubic spline analysis confirmed that these relationships were linear. The impact of age was significant, with OBS benefits only observed in those aged 40 and older.…”

Proteomic and Functional Analysis on Endothelial Cell Heterogeneity Identifies Key Regulators in Hyperglycemia-Induced Dysfunction-Supplemental Materials by Morgan Minjares (21143203)

“…Using proteomic analysis, we identified 126 proteins whose abundance was significantly different between HAECs and HDMVECs. …”

Supplementary file 1_Wetland degradation promotes soil P fraction transformation by altering P-cycling functional genes and metabolic pathways.docx by Yumeng Jiang (13036113)

“…Our results show that total inorganic P content decreased significantly with increasing degradation intensity. …”

Image_1_The causal effects of dietary component intake and blood metabolites on risk of delirium: a Mendelian randomization study.pdf by Qian Zhu (191342)

“…Inverse variance weighting, maximum likelihood, weighted median, weighted mode, and MR-Egger methods were used for statistical analyses.</p>Results<p>We found that genetic prediction of salt added to food (odds ratio [OR] 1.715, 95% confidence interval [CI] 1.239–2.374, p = 0.001) significantly increased the risks of delirium, while low-fat polyunsaturated margarine used in cooking (OR 0.044, 95%CI 0.004–0.432, p = 0.007), cheese intake (OR 0.691, 95%CI 0.500–0.955, p = 0.025) and coffee intake (OR 0.595, 95%CI 0.370–0.956, p = 0.032) was suggestively associated with decreased risks of delirium. …”

Table_1_The causal effects of dietary component intake and blood metabolites on risk of delirium: a Mendelian randomization study.xlsx by Qian Zhu (191342)

“…Inverse variance weighting, maximum likelihood, weighted median, weighted mode, and MR-Egger methods were used for statistical analyses.</p>Results<p>We found that genetic prediction of salt added to food (odds ratio [OR] 1.715, 95% confidence interval [CI] 1.239–2.374, p = 0.001) significantly increased the risks of delirium, while low-fat polyunsaturated margarine used in cooking (OR 0.044, 95%CI 0.004–0.432, p = 0.007), cheese intake (OR 0.691, 95%CI 0.500–0.955, p = 0.025) and coffee intake (OR 0.595, 95%CI 0.370–0.956, p = 0.032) was suggestively associated with decreased risks of delirium. …”