Table 4_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx by Bin Liao (714989)

“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”

Included studies. by Tong-jie Yang (20939652)

“…We systematically evaluated the key findings extracted from the included articles.…”

Table 3_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx by Bin Liao (714989)

“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”

Inclusion and exclusion criteria. by Tong-jie Yang (20939652)

“…We systematically evaluated the key findings extracted from the included articles.…”

Data Sheet 1_Efficacy and safety of reduning injection for severe pneumonia: a systematic review and meta-analysis.docx by Yan Wang (15435)

“…The primary outcomes was clinical efficacy. We used the Cochrane Risk of Bias Assessment Tool 2 (RoB 2) to assess the risk of bias for each study.…”

Table 6_Coordinated regulation of IGF1R by HIF1α and HIF2α enhances chemoresistance in glioblastoma.docx by Bin Liao (714989)

“…Simultaneous knockout of HIF1α and HIF2α in GBM cells resulted in the highest LDH release and apoptosis rates under hypoxic conditions, accompanied by the most significant decrease in IGF1R, p-PDK1, and p-AKT levels. …”

Table 1_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Table 2_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Table 1_Sensory reweighting for postural stability in individuals with low vision and blindness: balance adaptation and muscle co-contraction.xlsx by Yue Li (102191)

“…The rectus abdominis/erector spinae ratio decreased significantly with somatosensory deprivation, whereas the gastrocnemius/tibialis anterior co-contraction index increased significantly under both visual and somatosensory deprivation, with higher co-contraction observed in both low-vision and blind participants.…”

Data Sheet 1_TSG-6 promotes healing of critical-sized bone defects in mice.pdf by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Table 3_TSG-6 promotes healing of critical-sized bone defects in mice.xlsx by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Data Sheet 2_TSG-6 promotes healing of critical-sized bone defects in mice.pdf by Oliver Küppers (22742732)

“…Conversely, gremlin 1, a known inhibitor of osteoblastogenesis, was significantly upregulated. To investigate the in vivo relevance, we assessed the effects of locally delivered recombinant TSG-6 (rTSG-6), embedded in a collagen gel, on bone regeneration in a 1.5 mm critical-sized femoral defect model in male C57BL/6J mice. …”

Efficacy and safety of anticoagulation in asymptomatic cirrhotic patients with portal vein thrombosis: a systematic review and meta-analysis by Qingping Wu (789611)

“…Compared to no intervention, anticoagulation significantly increased the PVT recanalization rate (OR = 3.89, <i>p</i> < .001) and decreased the PVT progression rate (OR = 0.28, <i>p</i> < .001) as well as overall mortality (OR = 0.66, <i>p</i> = .008). …”

DataSheet1_Synergistic combinations of Angelica sinensis for myocardial infarction treatment: network pharmacology and quadratic optimization approach.docx by Wen-Di Wang (20400446)

“…Further research revealed that Z-LIG/CGA treatment significantly increased IL-1R2 levels, significantly decreased IL-17RA levels, and inhibited the activation of p-STAT1, thereby alleviating cell apoptosis after MI. …”

Legacy effects of trampling on SOC, POC, and MOC​ by yanchun liu (19650631)

“…Our results showed that in 2015, soil inorganic nitrogen (SIN), fine root biomass (FRB), and microbial biomass C decreased significantly with increasing trampling intensity, whereas the negative effects weakened over the recovery period. …”

Data Sheet 1_Antimycobacterial and immunomodulatory activities of sorafenib in a preclinical mouse model of TB infection through CD4+CD25low and CD8+CD25low effector T cells.pdf by Raju S. Rajmani (11134060)

“…In the current study, we documented a new immune modulatory characteristic of sorafenib that, upon SRB treatment, markedly increased effector T cells (Teff - CD4⁺CD25^low and CD8⁺CD25^low) activity and decreased regulatory T cells, the immunosuppressive T cells (Treg- CD4⁺CD25^high and CD8⁺CD25^high) function. …”

Data Sheet 2_Antimycobacterial and immunomodulatory activities of sorafenib in a preclinical mouse model of TB infection through CD4+CD25low and CD8+CD25low effector T cells.pdf by Raju S. Rajmani (11134060)

“…In the current study, we documented a new immune modulatory characteristic of sorafenib that, upon SRB treatment, markedly increased effector T cells (Teff - CD4⁺CD25^low and CD8⁺CD25^low) activity and decreased regulatory T cells, the immunosuppressive T cells (Treg- CD4⁺CD25^high and CD8⁺CD25^high) function. …”

Table1_Leishmania major surface components and DKK1 signalling via LRP6 promote migration and longevity of neutrophils in the infection site.docx by Olivia C. Ihedioha (19925886)

“…Relative to infected BALB/c mice, a significant reduction in parasite load was observed in both LRP6^NKO and LRP6^NKO DKK1^PKO infected mice. …”

SEAwise synthetic summary report of the findings of WP4 on changes to the ecosystem impacts of fishing in response to spatial management for online tool by Anna Rindorf (6217391)

“…The management scenarios investigated included fishing scenarios with different effort levels, closed areas and changes in relative effort of passive and active gears. We investigated whether scenarios with a higher proportion of landed stocks in good status also had a higher proportion of other ecological indicators in good status and the degree to which more restrictive, and risk adverse, management scenarios provided lower yields under current or future climate scenarios.…”

Supplementary Material for: Supportive care for common conditions in small vulnerable newborns and term infants: the evidence by Jiang L. (4145290)

“…Kangaroo mother care (KMC) significantly reduced SVN’s mortality by discharge. Early erythropoiesis stimulating agent lowered SVN’s risk of receiving blood transfusion. …”