Data Sheet 1_Decreased brain-derived neurotrophic factor expression in chronic kidney disease: integrated clinical and experimental evidence.docx by Juan Chen (61123)

“…Single-cell mRNA sequencing further confirmed that Bdnf levels were lower in renal proximal tubule (PT) cells, macrophages (Mφ), and podocytes in UUO mice compared to normal controls, Additionally, Bdnf-as—a long non-coding RNA known to epigenetically repress BDNF—was significantly upregulated in proximal tubules of CKD patients based on human transcriptomic data. …”

Table 1_Quantifying the effect of air pollution and temperature on hospitalization costs for chronic lower respiratory diseases.docx by Huanhuan Jia (2546878)

“…With respect to temperature, the hospitalization costs of people aged 60 and above increased by 8.70% on low-temperature days, and the exposure response ratio from lag day 0 to lag day 5 showed a statistically significant gradual decrease. Additionally, on lag days 5 and 11, the hospitalization costs of female patients with CLRDs increased by 3.35 and 3.92%, respectively.…”

Results of redundancy analysis. by Bianhua Zhang (22430652)

“…<div><p>In order to clarify the effects of long-term coal gangue(CG) dump on the surrounding soil bacterial community structure, we selected the CG dump formed during the mining of Tunlan coal mine in Gujiao city, Shanxi province in China as the study area to conduct a comprehensive study, the experimental design included six distinct zones: control soil area with no impaction (NC), undisturbed control sediment area (NL), atmospheric dry and wet deposition area (MC), upstream (MLS), midstream (MLZ) and downstream (MLX) in the leachate flow area (LFA), Using high-throughput sequencing technology and related software analysis, we obtained the following key findings: The heavy metal contents of Cr and Cd were different significantly in MC and NC (p < 0.05),Cr (90.18 mg·kg-1) in MC was higher than that in NC (65.29 mg·kg-1) (p < 0.05), while Cd (0.09 mg·kg-1) was lower than that in NC (0.14 mg·kg-1) (p < 0.05), and there was no significant differences in Cu, Zn, As and Pb between MC and NC (p > 0.05). …”

Forest plot depicting hazard ratios for the development of cardiovascular diseases. by Teng-Li Lin (5559284)

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Forest plot depicting hazard ratios for the development of any cardiovascular diseases stratified by biologic classes, demographics, regions of data source, and comorbidities. by Teng-Li Lin (5559284)

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Flow chart of the patient selection. by Teng-Li Lin (5559284)

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Demographic characteristics of study subjects after PSM ^* . by Teng-Li Lin (5559284)

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Cumulative incidence of any cardiovascular diseases in the BIO-cohort vs. the Non-BIO-cohort. by Teng-Li Lin (5559284)

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Table 1_Febuxostat may decrease the incidence of COVID-19 infection among patients with gout: a retrospective cohort study.docx by Weijie Wang (247184)

Demographic data of female participants (n = 30). by Vanessa Wellauer (18408477)

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Results of physiological parameters. by Vanessa Wellauer (18408477)

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Results of recovery parameters. by Vanessa Wellauer (18408477)

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Raw data used for statistical analysis. by Vanessa Wellauer (18408477)

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Schematic representation of the experimental protocol over time. by Vanessa Wellauer (18408477)

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Pairwise comparisons of the intervention effects by time point for physiological parameters. by Vanessa Wellauer (18408477)

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CONSORT flowchart of participants. by Vanessa Wellauer (18408477)

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Pairwise comparisons of the intervention effects by time point for recovery parameter. by Vanessa Wellauer (18408477)

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<b>The loss of insulin-positive cell clusters precedes the decrease of islet frequency and beta cell area in type 1 diabetes</b> by Denise M. Drotar (21679539)

“…Moreover, changes in endocrine composition also occurred in mAAb+ donors, including a significant decrease in the INS+ islet fraction. These data suggest preferential loss of INS+ small endocrine objects early in type 1 diabetes development.…”

Average Time Between Successive R-wave Peaks (RR Intervals) across pre-interview, interview and post-interview phases for High and Low Clarity and Authority groups: RR decreases fr... by David Vagni (8060432)

Image1_Association between mental health and male fertility: depression, rather than anxiety, is linked to decreased semen quality.tif by Yi Zhang (9093)

“…</p>Results<p>Status of depression was negatively associated with semen quality parameters, whereas no statistically significant association was recognized between anxiety and semen quality except that sperm concentration was decreased by 25.60 (95% CI, 1.226 to 49.965, P=0.040) ×10⁶/ml in moderate to severe anxiety group referring to normal group. …”