Tandem Imaging of Breath Ethanol and Acetaldehyde Based on Multiwavelength Enzymatic Biofluorometry by Kenta Iitani (4175995)

“…Reduction of AcH by ADH_RD consumed NADH, leading to a decrease in blue fluorescence (ex. 340 nm, fl. 490 nm). …”

Tandem Imaging of Breath Ethanol and Acetaldehyde Based on Multiwavelength Enzymatic Biofluorometry by Kenta Iitani (4175995)

“…Reduction of AcH by ADH_RD consumed NADH, leading to a decrease in blue fluorescence (ex. 340 nm, fl. 490 nm). …”

Amino acid metabolic pathways are influenced by the NC1 POM cycle over expression. by Bonnie A. McNeil (22331601)

“…The size of each circle reflects the number of “hits” relevant to the pathway with red having higher and yellow having lower significance based on <i><i>p</i></i>-value score.…”

Estimating RSA Variability across Treatment, Time, and Condition. by Hikari Otsuka (18605246)

Single-phage therapy succeeds against phage resistance with a strong enough immune system. by Jacopo Marchi (7252499)

Stacked bar chart illustrates the distribution of NMIBC, MIBC across age groups for males and females. by Yi Hong Li (21485068)

“…In age groups below 70, females demonstrated a comparable or slightly higher percentage of NMIBC compared to males, whereas in age groups above 70, the percentage of NMIBC was significantly lower in females. Conversely, the percentage of MIBC showed an opposite pattern, with higher proportions observed in females in the older age groups.…”

Source data for Fig 2. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for lung metabolomics. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 5. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 1. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Flow cytometry gating strategy for MDSC. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 3. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Source data for Fig 4. by Qi Xu (134661)

“…Our <i>ex vivo</i> inhibition experiment revealed that L-kynurenine, a product of tryptophan metabolism, inhibits T-cell proliferation and induces T-cell apoptosis, further suppressing T-cell mediated responses against bacteria. Importantly, when we knocked out the <i>Ido1</i> gene or inhibited IDO1 expression using a specific inhibitor 1-MT in mice, we observed a significant enhancement in T-cell mediated responses against hv<i>Kp</i>. …”

Cyclization Decoded: Engineering Amylomaltase for Efficient α‑Glucan Transformations by Han Liu (288039)

“…Enzyme kinetics results suggest that the improvement in enzyme performance largely stems from the decrease in enzyme–substrate affinity along the substrate transfer pathway. …”

Data extraction information. by Siyuan Chen (200219)

“…Additionally, GCA patients using biologic agents had significantly lower relapse rates and ESR levels with higher remission rates. …”

ROB 2.0 for RCT. by Siyuan Chen (200219)

“…Additionally, GCA patients using biologic agents had significantly lower relapse rates and ESR levels with higher remission rates. …”

All studies identified in the literature search. by Siyuan Chen (200219)

“…Additionally, GCA patients using biologic agents had significantly lower relapse rates and ESR levels with higher remission rates. …”

Participant characteristics by village. by Tyler M. Barrett (20846174)

“…We hypothesized that farmers with greater market-based wealth and more farming experience would have higher odds of adaptation. …”

School learning model dispositions data. by David A. Katz (10056006)

“…P-values<0.050 were considered significant. From 2019 to 2021, reported persistent feelings of sadness/hopelessness (2019 = 36.3%, 2021 = 41.3%), seriously considering suicide (17.0-18.7%), making suicide plan(s) (14.2-16.9%), and experiencing sexual dating violence in past 12 months (6.7-7.8%) increased significantly, while alcohol use (22.5-17.1%), binge drinking (8.5-6.2%), and marijuana use (20.2-14.3%) in past 30 days, ever prescription opioid misuse (16.0-13.2%), and gun-carrying (5.5-4.5%), physical fighting (22.3-17.3%), and any sexual violence (11.3-10.4%) in past 12 months decreased significantly. …”

Original data. by Kenji Sato (657309)

“…Additionally, a statistically significant improvement was observed in the Japanese Zarit Caregiver Burden Interview score at 6 months from baseline (p < 0.001).…”