Image 3_Low miR-936-mediated upregulation of Pim-3 drives sorafenib resistance in liver cancer through ferroptosis inhibition by activating the ANKRD18A/Src/NRF2 pathway.jpeg by Xiao Li (107004)

“…MiR-936 overexpression and GV102-Pim-3-shRNA significantly attenuated the activity of the ANKRD18A/Src/NRF2 pathway to decrease the expression of Ankyrin repeat domain-containing protein 18A (ANKRD18A), Src, and Nuclear factor (erythroid-derived 2)-like 2 (NRF2), especially decreasing NRF2 nuclear retention and transcriptional activity. …”

Table 1_Association between relative fat mass and risk of arthritis: a study based on populations in China and the United States.docx by Yang Yang (45629)

“…In the American female population, a non-linear correlation was observed between RFM and arthritis, with elevated RFM below the threshold of 35.85 exhibiting a modest decrease in the risk of arthritis, and elevated RFM above the threshold demonstrating a substantial increase in the risk of arthritis. …”

Datasheet1_Physiological characteristics of blood pressure responses after combined exercise in elderly hypertensive patients: a systematic review and meta-analysis.pdf by Zhiheng Li (525468)

“…</p>Results<p>In comparison to the control group (n = 194), individuals enrolled in the combined exercise group (n = 200) exhibited a notable decrease in both resting systolic blood pressure (SBP) [weighted mean difference (WMD) = −11.17 mm Hg, 95% confidence interval (CI) (−17.13, −5.22), Z = 3.68, P < 0.05] and diastolic blood pressure (DBP) [WMD = −5.93 mm Hg, 95% CI (−9.24, −2.61), Z = 3.51, P < 0.05]. …”

Paiva et al. data by Sergio Nogueira-Filho (10808859)

“…Pain assessment, clinical evaluation, and the measurement of heart rate (HR) and respiratory rate (RR) were conducted before and during ozone therapy. Ozone therapy significantly affected haemoglobin (F2,20=5.55; P=0.012), mean corpuscular haemoglobin concentrations (MCHC) (F2,20=16.01; P<0.001), and serum aspartate aminotransferase (AST) activity (F2,20=20.49; P<0.001). …”

Table 1_Effect of a mindfulness-based cognitive behavior therapy intervention on occupational burnout among school teachers.docx by Netra Raj Paudel (20610806)

“…</p>Results<p>The mean level of EE decreased during the post-test for both treatment (mean change -0.93, 95% CI: -2.56 to 0.70) and control (-1.71, 95% CI: -3.24 to -0.18) arms. …”

The SARS-CoV-2 (COVID-19) pandemic and diagnosis and treatment of women with abnormal uterine bleeding: findings from Brazil by Ilza Monteiro (10459778)

“…</p> <p>Fully completed questionnaires were received from 541 physicians aged (mean ± SD) 46.6 ± 12.5 years. Whereas the overall number of AUB-related visits decreased (<i>p</i> < 0.001) compared to the pre-pandemic period, the reduction was in office-based encounters; AUB-related visits at emergency facilities did not change. …”

Sleep deprivation by payam saidie (20329440)

“…Furthermore, in the NSP group, a significant decrease was observed at BASE compared to 60 min-PS (P ≤ 0.05) (20.72%).…”

BMI and sex disparity in uric acid level improvement in patients with obesity and diabetes following laparoscopic sleeve gastrectomy by Bian Wu (111324)

“…For lipid metabolism, a significant linear correlation was only observed between UA level changes and HDL in female and those with high presurgical UA levels.…”

Table_1_Efficacy of integrated traditional Chinese and western medicine in managing mild-moderate acute pancreatitis: a real-world clinical perspective analysis.docx by Sailei Jia (19966413)

“…</p>Results<p>Compared with the control group, the ITCWM group significantly decreased C-reactive protein (CRP, mg/L) (17.8 [1.2–59.5] vs. 8.0 [3.3–33.5], P = 0.022), shortened the duration of abdominal distension, abdominal pain, nausea and bitter taste symptoms (P < 0.05), and shortened the length of hospital stay (median 19.0 and 11.5 days, respectively, P = 0.001); Compared with the other two groups, the neutrophil percentage (NEUT%) was lower (74.1 vs. 61.9 vs. 59.5, P < 0.05) and serum prealbumin (PA, mg/L) was higher (116.0 vs. 184.4 vs. 220.0, P < 0.05), the length of hospitalization (days) was shortened (19.0 vs.12.0 vs.10.0, P < 0.05) in the OCM+E group.…”

Table_1_Efficacy of integrated traditional Chinese and western medicine in managing mild-moderate acute pancreatitis: a real-world clinical perspective analysis.docx by Sailei Jia (19966413)

“…</p>Results<p>Compared with the control group, the ITCWM group significantly decreased C-reactive protein (CRP, mg/L) (17.8 [1.2–59.5] vs. 8.0 [3.3–33.5], P = 0.022), shortened the duration of abdominal distension, abdominal pain, nausea and bitter taste symptoms (P < 0.05), and shortened the length of hospital stay (median 19.0 and 11.5 days, respectively, P = 0.001); Compared with the other two groups, the neutrophil percentage (NEUT%) was lower (74.1 vs. 61.9 vs. 59.5, P < 0.05) and serum prealbumin (PA, mg/L) was higher (116.0 vs. 184.4 vs. 220.0, P < 0.05), the length of hospitalization (days) was shortened (19.0 vs.12.0 vs.10.0, P < 0.05) in the OCM+E group.…”

Data Sheet 1_Intelligent pressure-controlled percutaneous unroofing: advancing minimally invasive renal cyst treatment.pdf by Haijun Liao (13851617)

“…Additionally, patients in the IPC-PURC group reported lower postoperative pain scores (p < 0.001). No significant differences were observed between the two groups in terms of hemoglobin decrease or complication rates. …”

pone.0331193.t003 - by Carol Kotliar (22351525)

“…</p><p>Conclusions</p><p>The MTT24.5 program, based on a systematic algorithm for acquiring new knowledge and skills, significantly enhances cognitive reserve and overall cognitive performance, particularly in individuals with lower baseline cognitive scores. …”

Baseline characteristics by group. by Carol Kotliar (22351525)

“…</p><p>Conclusions</p><p>The MTT24.5 program, based on a systematic algorithm for acquiring new knowledge and skills, significantly enhances cognitive reserve and overall cognitive performance, particularly in individuals with lower baseline cognitive scores. …”

Related to Fig 2. by Mohammad Nafees Ansari (22232505)

“…(<b>C</b>) Cell proliferation studies show a decrease in the proliferation of BT-474_RICTOR^SH cells (mean ± SEM, <i>n</i> = 3) compared to BT-474_SCRAM^SH cells. …”

Data Sheet 1_Lack of association between genetic variations in CYP3A5 and blood pressure or hypertension risk in the UK biobank.pdf by Pia Leibold (21390134)

“…In a sensitivity analysis based on different racial subgroups, only White participants showed significant associations between the CYP3A5*3 variant and slightly higher DBP (β = 0.10 mmHg, 95% CI: 0.02 to 0.18, P = 0.01), as well as between genotype-predicted CYP3A5 activity score and slightly lower DBP (β = −0.10 mmHg, 95% CI: −0.18 to −0.02, P = 0.01). …”

Table 1_Changes in self-reported alcohol consumption at high and low consumption in the wake of the COVID-19 pandemic: a test of the polarization hypothesis.docx by Alexander Tran (11038679)

“…</p>Results<p>Alcohol consumption decreased from 2015 to 2020, mean = 11.49 cl of pure alcohol (SD = 8.23) vs. mean = 10.71 cl of pure alcohol (SD = 12.12), p <.00001, respectively. …”

Data Sheet 1_Interannual variability of the Barents Sea branch water in the northeastern part of the Barents Sea and the St. Anna Trough.pdf by Zinaida Zabudkina (14771266)

“…The observed warming of BSBW accompanied by its salinity decrease, which is observed during the last 15 years, could significantly affect thermohaline structure and circulation in the Arctic Ocean.…”

DataSheet1_Risk of bone fracture by using dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors in patients wit... by Mohamed E. A. Mostafa (19834779)

“…The risk of fracture was identified with the follow-up duration for each class. We found a significant decrease in the fracture risk by about 87% associated with patients who used SGLT2 inhibitors in combination with other glucose-lowering medications, followed by SGLT2 inhibitors alone by about 67%, then GLP-1 receptor agonists by about 60%, and at last DPP-4 inhibitors by about 55%.…”

DataSheet2_Risk of bone fracture by using dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors in patients wit... by Mohamed E. A. Mostafa (19834779)

“…The risk of fracture was identified with the follow-up duration for each class. We found a significant decrease in the fracture risk by about 87% associated with patients who used SGLT2 inhibitors in combination with other glucose-lowering medications, followed by SGLT2 inhibitors alone by about 67%, then GLP-1 receptor agonists by about 60%, and at last DPP-4 inhibitors by about 55%.…”

DataSheet3_Risk of bone fracture by using dipeptidyl peptidase-4 inhibitors, glucagon-like peptide-1 receptor agonists, or sodium-glucose cotransporter-2 inhibitors in patients wit... by Mohamed E. A. Mostafa (19834779)

“…The risk of fracture was identified with the follow-up duration for each class. We found a significant decrease in the fracture risk by about 87% associated with patients who used SGLT2 inhibitors in combination with other glucose-lowering medications, followed by SGLT2 inhibitors alone by about 67%, then GLP-1 receptor agonists by about 60%, and at last DPP-4 inhibitors by about 55%.…”