Image 2_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Table 1_Protein-free domains in native and ferroptosis-driven oxidized cell membranes: a molecular dynamics study of biophysical properties and doxorubicin uptake.pdf by Yaser Shabanpour (13247160)

“…Furthermore, lipid oxidation affected diffusion activation energies. Importantly, we found that DOX could penetrate the oxidized ferroptosis membrane with a lower free-energy barrier (∆G_PB) of approximately 38 kJ.mol⁻¹. …”

Table 3_Protein-free domains in native and ferroptosis-driven oxidized cell membranes: a molecular dynamics study of biophysical properties and doxorubicin uptake.docx by Yaser Shabanpour (13247160)

“…Furthermore, lipid oxidation affected diffusion activation energies. Importantly, we found that DOX could penetrate the oxidized ferroptosis membrane with a lower free-energy barrier (∆G_PB) of approximately 38 kJ.mol⁻¹. …”

Image 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.tif by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Supplementary file 1_The effects of vessel speed and size on the lethality of strikes of large whales in U.S. waters.xlsx by Lance P. Garrison (2469937)

“…We found a significant effect of vessel size class on the probability of lethality. …”

Table1_Rethinking the prognosis model of differentiated thyroid carcinoma.docx by Liang He (305820)

“…More patients were classified as stage I, and the number of stage IV patients decreased significantly. The new system had a higher proportion of variance explained (PVE) (5.04%) and lower Akaike information criterion (AIC) (18,331.906) than the 8th TNM staging system (a PVE of 4.11% and AIC of 18,692.282). …”

Data Sheet 1_Protein-free domains in native and ferroptosis-driven oxidized cell membranes: a molecular dynamics study of biophysical properties and doxorubicin uptake.pdf by Yaser Shabanpour (13247160)

“…Furthermore, lipid oxidation affected diffusion activation energies. Importantly, we found that DOX could penetrate the oxidized ferroptosis membrane with a lower free-energy barrier (∆G_PB) of approximately 38 kJ.mol⁻¹. …”

Image 1_Protein-free domains in native and ferroptosis-driven oxidized cell membranes: a molecular dynamics study of biophysical properties and doxorubicin uptake.pdf by Yaser Shabanpour (13247160)

“…Furthermore, lipid oxidation affected diffusion activation energies. Importantly, we found that DOX could penetrate the oxidized ferroptosis membrane with a lower free-energy barrier (∆G_PB) of approximately 38 kJ.mol⁻¹. …”

Data Sheet 1_GPER1 signaling restricts macrophage proliferation and accumulation in human hepatocellular carcinoma.pdf by Yanyan Yang (412382)

“…The expression of G protein–coupled estrogen receptor 1 (GPER1), a non-classical estrogen receptor, was significantly decreased in proliferating macrophages, and was inversely correlated with macrophage proliferation in HCC tumors. …”

Supplementary file 2_The effects of vessel speed and size on the lethality of strikes of large whales in U.S. waters.docx by Lance P. Garrison (2469937)

“…We found a significant effect of vessel size class on the probability of lethality. …”

Data Sheet 1_Changes in the community composition and function of the rhizosphere microbiome in tobacco plants with Fusarium root rot.docx by Min Yang (146229)

“…In the root tissues of diseased plants, the Shannon index of bacterial and fungal communities decreased by 17.71–27.05% (P < 0.05). Additionally, we observed that the rhizosphere microbial community of diseased tobacco plants shifted toward a pathological combination, with a significant increase in the relative abundance of harmful microbes such as Alternaria, Fusarium, and Filobasidium (89.46–921.29%) and a notable decrease in the relative abundance of beneficial microbes such as Lysobacter, Streptomyces, Mortierella, and Penicillium (48.48–81.56%). …”

Table1_Evaluation of thyroid function tests among children with neurological disorders.docx by Haojie Meng (20400383)

“…Compared with controls, free thyroxine (FT4) levels were significantly decreased in neurological disorders in meta-analysis (MD = -0.29, 95% CI: -0.50 to -0.09), whereas thyroid-stimulating hormone (TSH) levels showed no significant difference (MD = -0.07, 95% CI: -0.36 to 0.21). …”

Table 1_Effects of different dosages/frequency of Xuebijing injection (a Chinese patent) for sepsis: a network meta-analysis of randomized controlled trials.docx by Guangyan Liu (716821)

“…</p>Methods<p>We examined eight databases for 1,765 randomized controlled trials published before July 2024, organized the literature using NoteExpress software and extracted data using Microsoft Excel software. …”

Image 3_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.jpeg by Bruno K. Rodiño-Janeiro (20565584)

“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”

Data Sheet 2_Acute stress triggers sex-dependent rapid alterations in the human small intestine microbiota composition.csv by Bruno K. Rodiño-Janeiro (20565584)

“…</p>Results<p>Cold pain stress was associated with a significant decrease in alpha diversity (P = 0.015), which was more pronounced in females, along with significant sex differences in the abundance of specific taxa and the overall microbiota composition. …”

Data from: '<b>From climate warming to accelerated cellular ageing: an experimental study in a wild passerine bird'</b> by Antoine Stier (3596369)

“…</i> higher thyroid hormones levels, increased expression of glucocorticoid receptor, increased mitochondrial density) leading to a reduction in telomere maintenance mechanisms (<i>i.e.</i> non-significant decrease in the gene expression of telomerase and protective shelterin). …”

Table 1_Targeting APE1/Ref-1 to alleviate formalin-induced pain and spinal neuro-inflammation in rats: a promising therapeutic approach.xlsx by Eman Elgendy (21811052)

“…We inhibited the redox function of APE1 using E3330 and assessed its effects on pain behavior. …”

DataSheet1_Role of Rab10 in cocaine-induced behavioral effects is associated with GABAB receptor membrane expression in the nucleus accumbens.DOCX by Zhuoxuan Yu (20343486)

“…Membrane levels of Rab10 increased within day 1 of the cocaine treatment, subsequently decreasing at later time points. Rab10 deficiency in NAc regions significantly increased cocaine-inhibited membrane GABA_BR levels and inhibited cocaine-induced hyperlocomotion and behavioral sensitization. …”

Data Sheet 4_Combined treatment with anti-PSMA antibody and human peripheral blood-derived NK cells for castration-resistant prostate cancer.docx by Fangming Wang (2810719)

“…CD16 is abundantly expressed in PB-NK cells. The anti-PSMA Ab significantly enhanced the cytotoxicity of NK cells against CRPC cells in vitro, evidenced by increased killing rate, upregulation of the degranulation marker CD107a, increased secretion of interferon-γ, and decreased PSA levels. …”

Model fit for childhood CHI subscales. by Amalie Hundahl (22593238)

“…With increasing CHI scores, we observed a decrease in well-being (p = 0.004), and health-related quality of life (p=<0.0001–0.007). …”